Phenylalanyl-tRNA synthetase 2, mitochondrial (FARS2)

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UGID:699706 UniGene Hs.484547 Homo sapiens (human) FARS2

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Phenylalanyl-tRNA synthetase 2, mitochondrial (FARS2)

Human protein-coding gene FARS2. Represented by 202 ESTs from 115 cDNA libraries. Corresponds to reference sequence NM_006567.3. [UniGene 699706 - Hs.484547]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_006558.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	FARS2 gene product	H. sapiens	100.0	450
NP_001233392.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	FARS2 gene product	P. troglodytes	99.8	450
NP_077236.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	phenylalanine--tRNA ligase, mitochondrial isoform 1	M. musculus	90.0	450
NP_001099064.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	fars2 gene product	D. rerio	74.7	418
NP_001256889.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein FARS-2, isoform c	C. elegans	56.4	424
NP_477283.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Phenylalanyl-tRNA synthetase	D. melanogaster	55.8	445
NP_567061.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	phenylalanyl-tRNA synthetase	A. thaliana	52.8	357
XP_001701674.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	predicted protein	C. reinhardtii	52.1	352
XP_956961.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	phenylalanyl-tRNA synthetase, mitochondrial precursor	N. crassa	50.0	209
NP_015372.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	phenylalanine--tRNA ligase	S. cerevisiae	47.2	196
Other hits (2 of 55) [Show all]		Species	Id(%)	Len(aa)
XP_003897052.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: phenylalanine--tRNA ligase, mitochondrial isoform 1	P. anubis	97.1	450
XP_002803632.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: phenylalanyl-tRNA synthetase, mitochondrial-like	M. mulatta	97.0	264

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	uncharacterized tissue; brain; pituitary gland; stomach; testis; connective tissue; mixed; kidney; placenta; bone marrow; intestine; pancreas; mammary gland; pharynx; blood; lung; heart; embryonic tissue; skin; bone; umbilical cord; ovary; liver; prostate; uterus; cervix; eye; parathyroid

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	6
Map position:	6p25.1
UniSTS entry:	Chr 6	A003M42	[Map Viewer]
UniSTS entry:	Chr 6	RH46741	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AF097441.1	Homo sapiens phenylalanine-tRNA synthetase (FARS1) mRNA, nuclear gene encoding mitochondrial protein, complete cds	PA
NM_006567.3	Homo sapiens phenylalanyl-tRNA synthetase 2, mitochondrial (FARS2), nuclear gene encoding mitochondrial protein, mRNA	P
AK001146.1	Homo sapiens cDNA FLJ10284 fis, clone HEMBB1001346, weakly similar to Homo sapiens phenylalanine-tRNA synthetase mRNA
CR542279.1	Homo sapiens full open reading frame cDNA clone RZPDo834F0926D for gene FARS1, phenylalanine-tRNA synthetase 1 (mitochondrial); complete cds, without stopcodon	P
AK223423.1	Homo sapiens mRNA for phenylalanine-tRNA synthetase 2 variant, clone: FCC110D03	PA
BC021112.1	Homo sapiens phenylalanyl-tRNA synthetase 2, mitochondrial, mRNA (cDNA clone MGC:31883 IMAGE:5088776), complete cds	PA
BC020239.1	Homo sapiens phenylalanyl-tRNA synthetase 2, mitochondrial, mRNA (cDNA clone MGC:31969 IMAGE:5258249), complete cds	PA
AK312454.1	Homo sapiens cDNA, FLJ92809, highly similar to Homo sapiens phenylalanine-tRNA synthetase 1 (mitochondrial)(FARS1), nuclear gene encoding mitochondrial protein, mRNA	P
AF161438.1	Homo sapiens HSPC320 mRNA, partial cds	PA

EST sequences (10 of 202) [Show all sequences]

AA971062.1	Clone IMAGE:1582146	mixed	3' read	A
R18207.1	Clone IMAGE:30559	brain	5' read	P
BX104547.1	Clone IMAGp998P21782_;_IMAGE:342788	heart		P
CB159658.1	Clone L18POOL1n1-25-D10	liver	5' read	P
AI338405.1	Clone IMAGE:1939289	embryonic tissue	3' read	PA
AI419829.1	Clone IMAGE:2112379	mixed	3' read	PA
AI675892.1	Clone IMAGE:2314428	prostate	3' read	A
AI766913.1	Clone IMAGE:2400604	kidney	3' read
AI796358.1	Clone IMAGE:2401593	kidney	3' read	PA
AI827016.1	Clone IMAGE:2421009	pancreas	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria