> Nipped-B homolog (Drosophila) (NIPBL)
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UGID:697086     UniGene Hs.481927     Homo sapiens (human)   NIPBL Links
Nipped-B homolog (Drosophila) (NIPBL)

Human protein-coding gene NIPBL. Represented by 357 ESTs from 188 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 697086 - Hs.481927]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_597677.2 NIPBL gene product H. sapiens 100.0 2803
XP_001146090.1 PREDICTED: nipped-B-like protein isoform 3 P. troglodytes 100.0 2803
XP_003899635.1 PREDICTED: nipped-B-like protein-like, partial P. anubis 99.8 497
XP_001096575.1 PREDICTED: nipped-B-like protein isoform 4 M. mulatta 99.6 2803
NP_081983.2 Nipbl gene product M. musculus 98.3 2797
NP_001086437.1 Nipped-B homolog X. laevis 85.4 2931
NP_001154919.1 nipped-B-like protein D. rerio 77.1 2855
NP_001163052.1 Nipped-B, isoform G D. melanogaster 56.4 413
NP_493687.2 Protein PQN-85 C. elegans 47.3 203
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_001499597.1 PREDICTED: nipped-B-like protein E. caballus 99.1 2804
XP_546344.2 PREDICTED: nipped-B-like protein isoform 1 C. lupus familiaris 99.1 2803

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uterus; embryonic tissue; skin; uncharacterized tissue; lung; pharynx; stomach; kidney; placenta; ovary; vascular; testis; eye; mammary gland; liver; ear; mouth; amniotic fluid; connective tissue; blood; esophagus; thymus; bone; pancreas; prostate; lymph node; thyroid; lymph; trachea; ascites; heart; parathyroid; intestine; bladder; adrenal gland; nerve; ganglia; cervix; muscle; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5p13.2
UniSTS entry: Chr 5 RH76750
UniSTS entry: Chr 5 RH47582 [Map Viewer]
UniSTS entry: Chr 5 MARC_21845-21846:1025102921:1
UniSTS entry: Chr 8 D8S1938
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BX538178.1 Homo sapiens mRNA; cDNA DKFZp686O04173 (from clone DKFZp686O04173) PA
BX538177.1 Homo sapiens mRNA; cDNA DKFZp686N05173 (from clone DKFZp686N05173) PA
BX640644.1 Homo sapiens mRNA; cDNA DKFZp686J10142 (from clone DKFZp686J10142) PA
AK126804.1 Homo sapiens cDNA FLJ44854 fis, clone BRACE3052410, highly similar to Homo sapiens IDN3 protein (IDN3) P
AK002065.1 Homo sapiens cDNA FLJ11203 fis, clone PLACE1007791, highly similar to Homo sapiens IDN3-B mRNA P
AL137726.1 Homo sapiens mRNA; cDNA DKFZp434L1319 (from clone DKFZp434L1319) PA
AJ640137.1 Homo sapiens mRNA for delangin (NIPBL gene), variant B P
AJ627032.1 Homo sapiens mRNA for delangin (NIPBL gene), variant A P
NM_015384.4 Homo sapiens Nipped-B homolog (Drosophila) (NIPBL), transcript variant B, mRNA P
AY726600.1 Homo sapiens clone MO-31 mRNA sequence P
AK022659.1 Homo sapiens cDNA FLJ12597 fis, clone NT2RM4001371, highly similar to Homo sapiens IDN3 mRNA P
AK023416.1 Homo sapiens cDNA FLJ13354 fis, clone PLACE1000004, highly similar to Homo sapiens IDN3-B mRNA P
BC131490.1 Homo sapiens Nipped-B homolog (Drosophila), mRNA (cDNA clone IMAGE:40071307), complete cds P
BC146821.1 Homo sapiens Nipped-B homolog (Drosophila), mRNA (cDNA clone IMAGE:8860431), partial cds PA
AK290347.1 Homo sapiens cDNA FLJ75519 partial cds P
NM_133433.3 Homo sapiens Nipped-B homolog (Drosophila) (NIPBL), transcript variant A, mRNA P
BC033847.1 Homo sapiens Nipped-B homolog (Drosophila), mRNA (cDNA clone IMAGE:4498111), complete cds PA
BC032711.1 Homo sapiens Nipped-B homolog (Drosophila), mRNA (cDNA clone IMAGE:5496103), with apparent retained intron PA

EST sequences (10 of 357) [Show all sequences]

AA961028.1 Clone IMAGE:1575132 kidney 3' read
R09094.1 Clone IMAGE:127553 mixed 3' read A
AA995226.1 Clone IMAGE:1625874 mixed 3' read A
AA909045.1 Clone IMAGE:1523205 mixed 3' read A
AI031815.1 Clone IMAGE:1645955 parathyroid 3' read
AI091170.1 Clone IMAGE:1566532 mixed 3' read
AI091329.1 Clone IMAGE:1566592 mixed 3' read
BX092252.1 Clone IMAGp998J071016_;_IMAGE:432486 mixed P
CB162827.1 Clone L17N670205n1-31-H06 liver 5' read P
AI200682.1 Clone IMAGE:1758170 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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