> 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR)
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UGID:696710     UniGene Hs.481551     Homo sapiens (human)   MTRR Order cDNA clone, Links
5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR)

Human protein-coding gene MTRR. Represented by 301 ESTs from 155 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 696710 - Hs.481551]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_076915.2 MTRR gene product H. sapiens 100.0 724
XP_001145250.1 PREDICTED: uncharacterized protein LOC461717 isoform 4 P. troglodytes 99.6 724
NP_766068.1 Mtrr gene product M. musculus 83.5 695
XP_689157.2 PREDICTED: methionine synthase reductase D. rerio 64.3 693
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_003899538.1 PREDICTED: methionine synthase reductase P. anubis 97.5 713
XP_002804366.1 PREDICTED: methionine synthase reductase-like M. mulatta 96.7 703

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; blood; embryonic tissue; uncharacterized tissue; pancreas; lymph node; spinal cord; placenta; skin; mixed; mammary gland; uterus; prostate; liver; muscle; vascular; bladder; mouth; thymus; bone marrow; ovary; trachea; kidney; intestine; cervix; connective tissue; spleen; heart; thyroid; ascites; parathyroid; pharynx; eye; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5p15.31
UniSTS entry: Chr 5 RH11562 [Map Viewer]
UniSTS entry: Chr 5 A002A03 [Map Viewer]
UniSTS entry: Chr 5 G19837
UniSTS entry: Chr 5 STS-N29717
UniSTS entry: Chr 5 MTRR_214
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC054816.1 Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase, mRNA (cDNA clone MGC:61524 IMAGE:5205285), complete cds PA
NM_002454.2 Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 1, mRNA PA
BC062577.1 Homo sapiens cDNA clone IMAGE:5189058, containing frame-shift errors PA
AF121214.1 Homo sapiens methionine synthase reductase (MTRR) mRNA, complete cds PA
BC109216.1 Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase, mRNA (cDNA clone MGC:129643 IMAGE:40007734), complete cds P
BC109217.1 Homo sapiens cDNA clone IMAGE:40007736, containing frame-shift errors P
NM_024010.2 Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR), transcript variant 2, mRNA PA
AK311663.1 Homo sapiens cDNA, FLJ18705 P
AK308442.1 Homo sapiens cDNA, FLJ98390 P
BC035977.1 Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase reductase, mRNA (cDNA clone IMAGE:4611253), containing frame-shift errors PA
AF025794.1 Homo sapiens methionine synthase reductase (MTRR) mRNA, complete cds PA

EST sequences (10 of 301) [Show all sequences]

AA905280.1 Clone IMAGE:1506121 mixed 3' read A
AA905139.1 Clone IMAGE:1523376 mixed 3' read A
R17835.1 Clone IMAGE:31776 brain 5' read P
AI016080.1 Clone IMAGE:1638494 testis 3' read PA
AI027905.1 Clone IMAGE:1650492 parathyroid 3' read A
AI033997.1 Clone IMAGE:1646683 parathyroid 3' read A
AI061048.1 Clone IMAGE:1699426 kidney 3' read A
AI080198.1 Clone IMAGE:1677345 mixed 3' read A
AI089223.1 Clone IMAGE:1695341 uterus 3' read A
AI091577.1 Clone IMAGE:1651119 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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