> NIMA-related kinase 1 (NEK1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:696340     UniGene Hs.481181     Homo sapiens (human)   NEK1 Order cDNA clone, Links
NIMA-related kinase 1 (NEK1)

Human protein-coding gene NEK1. Represented by 142 ESTs from 72 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 696340 - Hs.481181]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001186326.1 NEK1 gene product H. sapiens 100.0 1285
XP_526727.2 PREDICTED: serine/threonine-protein kinase Nek1 isoform 7 P. troglodytes 99.9 1285
NP_780298.2 serine/threonine-protein kinase Nek1 M. musculus 88.0 1202
NP_001085175.1 NIMA-related kinase 3 X. laevis 63.0 273
XP_001700340.1 predicted protein C. reinhardtii 61.7 277
NP_620776.1 nek8 gene product D. rerio 54.9 253
NP_491914.1 Protein NEKL-2 C. elegans 48.8 172
NP_651293.1 nimA-like kinase D. melanogaster 48.8 203
Other hits (2 of 44) [Show all]SpeciesId(%)Len(aa)
XP_003899404.1 PREDICTED: serine/threonine-protein kinase Nek1-like P. anubis 99.0 862
XP_001083275.1 PREDICTED: serine/threonine-protein kinase Nek1 isoform 5 M. mulatta 98.4 1285

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; brain; mixed; muscle; embryonic tissue; ear; testis; uterus; kidney; uncharacterized tissue; prostate; lung; bone marrow; intestine; heart; stomach; vascular; trachea; skin; eye; ganglia; bone; adrenal gland; ovary; lymph node; bladder; blood
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q33
UniSTS entry: Chr 4 SHGC-44466
UniSTS entry: Chr 4 SHGC-67657 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AL050385.1 Homo sapiens mRNA; cDNA DKFZp564L2416 (from clone DKFZp564L2416) PA
NM_012224.2 Homo sapiens NIMA-related kinase 1 (NEK1), transcript variant 2, mRNA PA
BC068201.1 Homo sapiens NIMA (never in mitosis gene a)-related kinase 1, mRNA (cDNA clone IMAGE:4771714) PA
CR933642.1 Homo sapiens mRNA; cDNA DKFZp686D06121 (from clone DKFZp686D06121) PA
AF155113.1 Homo sapiens NY-REN-55 antigen mRNA, partial cds P
CR936672.1 Homo sapiens mRNA; cDNA DKFZp686K12169 (from clone DKFZp686K12169) PA
AK024912.1 Homo sapiens cDNA: FLJ21259 fis, clone COL01416 A
AK025658.1 Homo sapiens cDNA: FLJ22005 fis, clone HEP06902 PA
BC114491.1 Homo sapiens NIMA (never in mitosis gene a)-related kinase 1, mRNA (cDNA clone MGC:138800 IMAGE:40082305), complete cds P
AK027580.1 Homo sapiens cDNA FLJ14674 fis, clone NT2RP2003912, highly similar to SERINE/THREONINE-PROTEIN KINASE NEK1 (EC 2.7.1.-) P
AB067488.1 Homo sapiens mRNA for KIAA1901 protein, partial cds P
BC015147.1 Homo sapiens NIMA (never in mitosis gene a)-related kinase 1, mRNA (cDNA clone IMAGE:4063881), partial cds PA
Z25431.1 H.sapiens protein-serine/threonine kinase gene, complete CDS
NM_001199400.1 Homo sapiens NIMA-related kinase 1 (NEK1), transcript variant 5, mRNA PA
NM_001199399.1 Homo sapiens NIMA-related kinase 1 (NEK1), transcript variant 4, mRNA PA
NM_001199398.1 Homo sapiens NIMA-related kinase 1 (NEK1), transcript variant 3, mRNA PA
NM_001199397.1 Homo sapiens NIMA-related kinase 1 (NEK1), transcript variant 1, mRNA PA
BC037790.2 Homo sapiens NIMA (never in mitosis gene a)-related kinase 1, mRNA (cDNA clone IMAGE:4792489), partial cds PA

EST sequences (10 of 142) [Show all sequences]

AI091019.1 Clone IMAGE:1689734 mixed 3' read P
AA907081.1 Clone IMAGE:1522354 lung 3' read P
BX096577.1 Clone IMAGp998N17639_;_IMAGE:287824 brain
AI205820.1 Clone IMAGE:1836990 testis 3' read A
CB138134.1 Clone L6ChoCK0-26-A08 liver 5' read
CB132355.1 Clone L14ChoiCK0-10-F11 liver 5' read P
CB139237.1 Clone L15CKK1-11-A08 liver 5' read
AI288543.1 Clone IMAGE:1879667 mixed 3' read P
AI342812.1 Clone IMAGE:1910587 lung 3' read P
AI378221.1 Clone IMAGE:2069472 mixed 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help