> Insulin-like growth factor binding protein 7 (IGFBP7)
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UGID:694967     UniGene Hs.479808     Homo sapiens (human)   IGFBP7 Order cDNA clone, Links
Insulin-like growth factor binding protein 7 (IGFBP7)

Human protein-coding gene IGFBP7. Represented by 1000 ESTs from 241 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 694967 - Hs.479808]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_517274.3 PREDICTED: insulin-like growth factor binding protein 7 P. troglodytes 100.0 281
NP_001544.1 IGFBP7 gene product H. sapiens 100.0 281
XP_001491221.2 PREDICTED: angiomodulin, partial E. caballus 100.0 149
XP_001083041.1 PREDICTED: insulin-like growth factor binding protein 7 isoform 4 M. mulatta 99.7 281
NP_032074.3 Igfbp7 gene product M. musculus 95.0 281
NP_998089.1 igfbp7 gene product D. rerio 62.1 252
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
NP_001095770.1 IGFBP7 gene product B. taurus 98.6 281
XP_003898898.1 PREDICTED: insulin-like growth factor-binding protein 7 P. anubis 98.3 354

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; testis; larynx; eye; intestine; lung; uterus; mixed; kidney; vascular; uncharacterized tissue; skin; placenta; amniotic fluid; stomach; ear; umbilical cord; embryonic tissue; connective tissue; heart; lymph node; adipose tissue; liver; ovary; bone marrow; bone; prostate; adrenal gland; mammary gland; nerve; thyroid; salivary gland; cervix; blood; ganglia; muscle; thymus; mouth; spleen; pituitary gland; tonsil; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q12
UniSTS entry: Chr 4 SHGC-12841 [Map Viewer]
UniSTS entry: Igfbp7
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Igfbp7
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BT006654.1 Homo sapiens insulin-like growth factor binding protein 7 mRNA, complete cds P
BX648756.1 Homo sapiens mRNA; cDNA DKFZp686B20109 (from clone DKFZp686B20109) A
NM_001553.2 Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), transcript variant 1, mRNA PA
BC066339.1 Homo sapiens insulin-like growth factor binding protein 7, mRNA (cDNA clone MGC:87449 IMAGE:5296697), complete cds PA
L19182.1 Human MAC25 mRNA, complete cds P
BC017201.2 Homo sapiens insulin-like growth factor binding protein 7, mRNA (cDNA clone MGC:3699 IMAGE:3632247), complete cds PA
AK303915.1 Homo sapiens cDNA FLJ56737 complete cds, highly similar to Insulin-like growth factor-binding protein 7 precursor P
AK316082.1 Homo sapiens cDNA, FLJ78981 complete cds, highly similar to Insulin-like growth factor-binding protein 7 precursor P
S75725.1 prostacyclin-stimulating factor [human, cultured diploid fibroblast cells, mRNA, 1124 nt] PA
NM_001253835.1 Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), transcript variant 2, mRNA P

EST sequences (10 of 1000) [Show all sequences]

AA968848.1 Clone IMAGE:1573812 kidney 3' read A
AA973981.1 Clone IMAGE:1585314 lung 3' read A
AI003460.1 Clone IMAGE:1414889 spleen 3' read A
AI024325.1 Clone IMAGE:1642436 testis 3' read A
AI037988.1 Clone IMAGE:1663874 skin 3' read A
AI040561.1 Clone IMAGE:1656360 mixed 3' read A
AI041288.1 Clone IMAGE:1642273 testis 3' read A
AI061218.1 Clone IMAGE:1700363 kidney 3' read A
AA946989.1 Clone IMAGE:1589302 kidney 3' read A
AI075686.1 Clone IMAGE:1667193 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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