> V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT)
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UGID:694913     UniGene Hs.479754     Homo sapiens (human)   KIT
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT)

Human protein-coding gene KIT. Represented by 168 ESTs from 93 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 694913 - Hs.479754]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000213.1 KIT gene product H. sapiens 100.0 975
XP_517285.3 PREDICTED: mast/stem cell growth factor receptor Kit P. troglodytes 99.9 971
NP_001116205.1 Kit gene product M. musculus 89.1 978
NP_001079048.1 mast/stem cell growth factor receptor-related protein Kit precursor X. laevis 69.2 952
NP_571128.1 kita gene product D. rerio 62.2 963
NP_496130.1 Overexpression Longevity Determinant family member (old-1) C. elegans 45.6 193
NP_476849.1 Src oncogene at 42A, isoform A D. melanogaster 45.3 161
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
XP_001089071.1 PREDICTED: mast/stem cell growth factor receptor M. mulatta 99.3 975
XP_003898931.1 PREDICTED: LOW QUALITY PROTEIN: mast/stem cell growth factor receptor Kit P. anubis 99.2 971

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; ovary; uncharacterized tissue; embryonic tissue; lung; eye; connective tissue; skin; muscle; adipose tissue; mixed; mammary gland; pancreas; liver; spleen; testis; placenta; trachea; uterus; kidney; intestine; heart; thymus; umbilical cord; bladder; ear; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q11-q12
UniSTS entry: Chr 4 SHGC-67781
UniSTS entry: Chr 4 STS-N21003 [Map Viewer]
UniSTS entry: Chr 4 SHGC-50170
UniSTS entry: Chr 4 G15879
UniSTS entry: Chr 4 GDB:512789
UniSTS entry: Chr 4 SHGC4-128 [Map Viewer]
UniSTS entry: Chr 4 SHGC-12679 [Map Viewer]
UniSTS entry: Kit
UniSTS entry: Chr 4 GDB:181531
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_000222.2 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 1, mRNA PA
BC071593.1 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, mRNA (cDNA clone MGC:87427 IMAGE:4375615), complete cds PA
NM_001093772.1 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 2, mRNA PA
EU826594.1 Homo sapiens soluble KIT variant 1 (KIT) mRNA, complete cds, alternatively spliced P
AK304031.1 Homo sapiens cDNA FLJ54320 complete cds, highly similar to Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) P
AJ438313.1 Homo sapiens partial mRNA for KIT protein P
X06182.1 Human c-kit proto-oncogene mRNA P
GU983671.1 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein transcript variant 2 (KIT) mRNA, complete cds, alternatively spliced P
HM030713.1 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein transcript variant 1 (KIT) mRNA, partial cds, alternatively spliced P
HM030712.1 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein transcript variant 2 (KIT) mRNA, partial cds, alternatively spliced P
HM015526.1 Homo sapiens cell-line SH-SY5Y v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein transcript variant 2 (KIT) mRNA, complete cds, alternatively spliced P
HM015525.1 Homo sapiens cell-line Kelly v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein (KIT) mRNA, complete cds P
HM437240.1 Homo sapiens mast/stem cell growth factor receptor variant (KIT) mRNA, partial cds

EST sequences (10 of 168) [Show all sequences]

AI017093.1 Clone IMAGE:1627938 mixed 3' read
AI051302.1 Clone IMAGE:1657266 embryonic tissue 3' read
AI122936.1 Clone IMAGE:1509492 mixed 3' read A
AI143554.1 Clone IMAGE:1708520 heart 3' read A
CB053658.1 Clone IMAGE:3291078 uncharacterized tissue 3' read A
CB053659.1 Clone IMAGE:3291078 uncharacterized tissue 5' read
BX095010.1 Clone IMAGp998O01590_;_IMAGE:269016 skin
R35401.1 Clone IMAGE:37621 brain 5' read
AI308810.1 Clone IMAGE:1914093 kidney 3' read A
AI424892.1 Clone IMAGE:2111019 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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