> Tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10)
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UGID:693434     UniGene Hs.478275     Homo sapiens (human)   TNFSF10 Order cDNA clone, Links
Tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10)

Human protein-coding gene TNFSF10. Represented by 400 ESTs from 176 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 693434 - Hs.478275]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003801.1 TNFSF10 gene product H. sapiens 100.0 280
NP_001233349.1 TNFSF10 gene product P. troglodytes 99.6 280
NP_033451.1 Tnfsf10 gene product M. musculus 71.4 287
NP_001163915.1 tumor necrosis factor (ligand) superfamily, member 10 X. laevis 56.0 266
NP_001002593.1 tnfsf10 gene product D. rerio 54.1 181
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_001084768.1 PREDICTED: tumor necrosis factor ligand superfamily member 10 M. mulatta 97.5 280
XP_003894875.1 PREDICTED: tumor necrosis factor ligand superfamily member 10 P. anubis 97.5 280

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; kidney; lung; mammary gland; blood; ear; brain; prostate; intestine; uterus; ovary; heart; mixed; pharynx; uncharacterized tissue; vascular; pancreas; esophagus; thyroid; mouth; eye; larynx; adrenal gland; liver; spleen; testis; connective tissue; bladder; bone marrow; stomach; muscle; trachea; amniotic fluid; thymus; skin; lymph; ascites; umbilical cord; lymph node; embryonic tissue; parathyroid; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q26
UniSTS entry: Chr 3 RH66570 [Map Viewer]
UniSTS entry: Chr 3 SHGC-77549 [Map Viewer]
UniSTS entry: Chr 3 TNFSF10_266
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

NM_003810.3 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), transcript variant 1, mRNA PA
AY312579.1 Homo sapiens chemokine tumor necrosis factor ligand superfamily member 10 (TNFSF10) mRNA, partial cds, alternatively spliced
CR456895.1 Homo sapiens full open reading frame cDNA clone RZPDo834F0111D for gene TNFSF10, tumor necrosis factor (ligand) superfamily, member 10; complete cds, incl. stopcodon P
BT019564.1 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 mRNA, complete cds P
U37518.1 Human TNF-related apoptosis inducing ligand TRAIL mRNA, complete cds PA
DQ848564.1 Homo sapiens tumor necrosis factor ligand superfamily member 10 splice variant (TNFSF10) mRNA, complete cds, alternatively spliced P
U57059.1 Homo sapiens Apo-2 ligand mRNA, complete cds P
EU183231.1 Homo sapiens tumor necrosis factor apoptosis-inducing ligand splice variant delta mRNA, complete cds, alternatively spliced P
AK309200.1 Homo sapiens cDNA, FLJ99241
AK312742.1 Homo sapiens cDNA, FLJ93150, Homo sapiens tumor necrosis factor (ligand) superfamily, member 10(TNFSF10), mRNA P
BC032722.1 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10, mRNA (cDNA clone MGC:45300 IMAGE:5504670), complete cds PA
AK296085.1 Homo sapiens cDNA FLJ51976 complete cds, moderately similar to Tumor necrosis factor ligand superfamily member 10 PA
BC020220.1 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10, mRNA (cDNA clone IMAGE:4585594), containing frame-shift errors PA
BC009795.1 Homo sapiens, tumor necrosis factor (ligand) superfamily, member 10, clone IMAGE:4249793, mRNA PA
NM_001190943.1 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), transcript variant 3, mRNA
NM_001190942.1 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), transcript variant 2, mRNA P
NR_033994.1 Homo sapiens tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10), transcript variant 4, non-coding RNA PA

EST sequences (10 of 400) [Show all sequences]

AI026064.1 Clone IMAGE:1647275 parathyroid 3' read PA
AI091048.1 Clone IMAGE:1690447 mixed 3' read PA
AI095853.1 Clone IMAGE:1697383 uterus 3' read P
CB049026.1 Clone IMAGE:3270917 prostate 5' read
CB049025.1 Clone IMAGE:3270917 prostate 3' read A
CB070245.1 Clone IMAGE:6553464 pancreas 5' read P
AI262183.1 Clone IMAGE:1868436 kidney 3' read
R31020.1 Clone IMAGE:134175 placenta 5' read
CB118398.1 Clone L8SCK0-18-G06 liver 5' read P
CB127043.1 Clone C1SNU17-14-G09 cervix 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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