> Chromosome 22 open reading frame 28 (C22orf28)
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UGID:689802     UniGene Hs.474643     Homo sapiens (human)   C22orf28
Chromosome 22 open reading frame 28 (C22orf28)

Human protein-coding gene C22orf28. Represented by 1353 ESTs from 378 cDNA libraries. Corresponds to reference sequence NM_014306.4. [UniGene 689802 - Hs.474643]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_663397.1 D10Wsu52e gene product M. musculus 100.0 504
XP_001152688.1 PREDICTED: tRNA-splicing ligase RtcB homolog isoform 2 P. troglodytes 100.0 504
NP_055121.1 C22orf28 gene product H. sapiens 100.0 504
XP_531754.2 PREDICTED: tRNA-splicing ligase RtcB homolog C. lupus familiaris 100.0 504
XP_001499511.1 PREDICTED: tRNA-splicing ligase RtcB homolog E. caballus 100.0 504
NP_001116458.1 LOC733658 gene product S. scrofa 100.0 504
NP_001015631.1 C5H22orf28 gene product B. taurus 100.0 504
XP_004006754.1 PREDICTED: tRNA-splicing ligase RtcB homolog isoform 1 O. aries 100.0 504
XP_002711465.1 PREDICTED: hypothetical protein O. cuniculus 100.0 504
NP_997497.1 LOC362855 gene product R. norvegicus 99.8 504
XP_001366104.1 PREDICTED: tRNA-splicing ligase RtcB homolog M. domestica 99.8 504
XP_001112395.1 PREDICTED: UPF0027 protein C22orf28 homolog isoform 1 M. mulatta 99.8 504
NP_001162246.1 tRNA-splicing ligase RtcB homolog P. anubis 99.8 504
NP_998268.1 zgc:76871 gene product D. rerio 96.2 504
NP_001090369.1 uncharacterized protein LOC779280 X. laevis 96.2 504
NP_609965.1 CG9987 D. melanogaster 89.9 503
XP_001699521.1 predicted protein C. reinhardtii 83.2 475
NP_492498.1 Protein F16A11.2 C. elegans 79.6 504
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_416300.2 PREDICTED: tRNA-splicing ligase RtcB homolog G. gallus 99.4 504
XP_003202400.1 PREDICTED: UPF0027 protein C22orf28-like M. gallopavo 99.4 504

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; placenta; lung; skin; intestine; uterus; kidney; muscle; liver; ovary; mixed; connective tissue; thymus; embryonic tissue; adrenal gland; mammary gland; larynx; blood; eye; prostate; epididymis; thyroid; stomach; pharynx; heart; vascular; bone; spleen; cervix; bone marrow; lymph; ascites; salivary gland; pancreas; adipose tissue; umbilical cord; bladder; trachea; esophagus; mouth; lymph node; tonsil; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q12
UniSTS entry: Chr 22 A002Q35
UniSTS entry: Chr 22 D22S1242 [Map Viewer]
UniSTS entry: Chr 22 REN77702
UniSTS entry: RH136031
UniSTS entry: Chr 22 HSPC117_9724
UniSTS entry: Chr 22 REN77761
UniSTS entry: Chr 22 REN77788
UniSTS entry: Chr 22 REN77705
UniSTS entry: Chr 22 REN77808
UniSTS entry: Chr 22 REN77809
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AL050255.1 Novel gene similar to C. elegens hypothetical 55.2 KD protein F16A11.2, SW:P90838 P
AL137272.1 Homo sapiens mRNA; cDNA DKFZp434I1614 (from clone DKFZp434I1614) PA
CR456450.1 Homo sapiens dJ149A16.6 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.dJ149A16.6) P
CR457175.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0912D for gene HSPC117, hypothetical protein HSPC117; complete cds, incl. stopcodon P
NM_014306.4 Homo sapiens chromosome 22 open reading frame 28 (C22orf28), mRNA P
AF155658.1 Homo sapiens putative 55 kDa protein mRNA, complete cds PA
BC002970.1 Homo sapiens chromosome 22 open reading frame 28, mRNA (cDNA clone MGC:1849 IMAGE:3533883), complete cds PA
BC000151.1 Homo sapiens chromosome 22 open reading frame 28, mRNA (cDNA clone MGC:5036 IMAGE:2984824), complete cds PA
BC016707.1 Homo sapiens chromosome 22 open reading frame 28, mRNA (cDNA clone MGC:23730 IMAGE:4102148), complete cds PA
BC010308.1 Homo sapiens chromosome 22 open reading frame 28, mRNA (cDNA clone MGC:5037 IMAGE:3451576), complete cds PA
AK312503.1 Homo sapiens cDNA, FLJ92867 P
AK301945.1 Homo sapiens cDNA FLJ57223 complete cds P
AK297908.1 Homo sapiens cDNA FLJ57752 complete cds P
AK297826.1 Homo sapiens cDNA FLJ58027 complete cds P
AF161466.1 Homo sapiens HSPC117 mRNA, complete cds PA

EST sequences (10 of 1353) [Show all sequences]

R08877.1 Clone IMAGE:127521 mixed 3' read
AA886679.1 Clone IMAGE:1501501 kidney 3' read A
AI032760.1 Clone IMAGE:1656258 mixed 3' read
AA947397.1 Clone IMAGE:1587981 uncharacterized tissue 3' read
AA948653.1 Clone IMAGE:1588554 kidney 3' read
AI073637.1 Clone IMAGE:1664330 skin 3' read
AI092172.1 Clone IMAGE:1694265 heart 3' read
AI096378.1 Clone IMAGE:1707500 heart 3' read
AI131218.1 Clone IMAGE:1709341 heart 3' read
AI140974.1 Clone IMAGE:1750994 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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