> OTU domain, ubiquitin aldehyde binding 1 (OTUB1)
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UGID:688947     UniGene Hs.473788     Homo sapiens (human)   OTUB1
OTU domain, ubiquitin aldehyde binding 1 (OTUB1)

Human protein-coding gene OTUB1. Represented by 1118 ESTs from 366 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 688947 - Hs.473788]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003313090.1 PREDICTED: ubiquitin thioesterase OTUB1 P. troglodytes 100.0 307
NP_598911.1 ubiquitin thioesterase OTUB1 M. musculus 100.0 270
NP_001099802.1 Otub1 gene product R. norvegicus 100.0 270
XP_003909684.1 PREDICTED: ubiquitin thioesterase OTUB1 P. anubis 100.0 270
NP_060140.2 OTUB1 gene product H. sapiens 100.0 270
NP_001238876.1 ubiquitin thioesterase OTUB1 C. lupus familiaris 100.0 270
NP_001155875.1 OTUB1 gene product S. scrofa 100.0 270
XP_001115486.1 PREDICTED: ubiquitin thioesterase OTUB1 M. mulatta 100.0 264
NP_001029891.1 OTUB1 gene product B. taurus 99.6 270
XP_004019687.1 PREDICTED: ubiquitin thioesterase OTUB1 O. aries 99.6 240
NP_001002411.1 otub1a gene product D. rerio 85.8 266
NP_001089759.1 OTU domain, ubiquitin aldehyde binding 1 X. laevis 81.0 267
NP_609375.1 CG4968 D. melanogaster 62.1 250
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_001489344.1 PREDICTED: ubiquitin thioesterase OTUB1-like E. caballus 99.3 279
XP_003228011.1 PREDICTED: LOW QUALITY PROTEIN: ubiquitin thioesterase OTUB1-like, partial A. carolinensis 91.9 247

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; embryonic tissue; intestine; lung; placenta; testis; mixed; uterus; kidney; skin; eye; mammary gland; spleen; mouth; liver; bone marrow; salivary gland; cervix; lymph; ascites; stomach; blood; ovary; esophagus; thymus; prostate; pancreas; heart; bladder; muscle; connective tissue; tonsil; bone; pharynx; thyroid; vascular; amniotic fluid; ganglia; nerve; umbilical cord; lymph node; adrenal gland; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13.1
UniSTS entry: Chr 11 RH78815
UniSTS entry: Chr 11 SHGC-30562
UniSTS entry: Chr 11 RH102958
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AY177200.1 Homo sapiens ubiquitin-specific protease otubain 1 mRNA, complete cds P
AL096714.1 Homo sapiens mRNA; cDNA DKFZp564E242 (from clone DKFZp564E242) PA
AK000120.1 Homo sapiens cDNA FLJ20113 fis, clone COL05437 PA
NM_017670.2 Homo sapiens OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1, mRNA PA
BC107701.1 Homo sapiens OTU domain, ubiquitin aldehyde binding 1, mRNA (cDNA clone MGC:111158 IMAGE:6494629), complete cds PA
NR_003089.1 Homo sapiens OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 2, non-coding RNA PA
AK225133.1 Homo sapiens mRNA for Ubiquitin thiolesterase protein OTUB1 variant, clone: CBL02692 P
BC007519.2 Homo sapiens OTU domain, ubiquitin aldehyde binding 1, mRNA (cDNA clone MGC:4584 IMAGE:3051266), complete cds PA
BC010368.1 Homo sapiens OTU domain, ubiquitin aldehyde binding 1, mRNA (cDNA clone MGC:13444 IMAGE:4334279), complete cds PA
AK307413.1 Homo sapiens cDNA, FLJ97361 P
AK098029.1 Homo sapiens cDNA FLJ40710 fis, clone THYMU2027125, highly similar to Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) P
AK298287.1 Homo sapiens cDNA FLJ56307 complete cds, highly similar to Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) PA
AK303228.1 Homo sapiens cDNA FLJ61195 complete cds, highly similar to Ubiquitin thioesterase protein OTUB1 (EC 3.4.-.-) P
AF161381.1 Homo sapiens HSPC263 mRNA, partial cds PA

EST sequences (10 of 1118) [Show all sequences]

AA968853.1 Clone IMAGE:1573811 kidney 3' read A
AA987713.1 Clone IMAGE:1593417 kidney 3' read A
R16295.1 Clone IMAGE:30089 brain 5' read P
AA946762.1 Clone IMAGE:1589778 kidney 3' read A
AI124016.1 Clone IMAGE:1691472 heart 3' read A
R22844.1 Clone IMAGE:35776 brain 5' read
AI160737.1 Clone IMAGE:1703430 brain 3' read A
BX099050.1 Clone IMAGp998M23326_;_IMAGE:177982 brain P
AI262509.1 Clone IMAGE:1871553 intestine 3' read A
AI262840.1 Clone IMAGE:1871039 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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