> Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:688807     UniGene Hs.473648     Homo sapiens (human)   GART Order cDNA clone, Links
Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART)

Human protein-coding gene GART. Represented by 685 ESTs from 259 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 688807 - Hs.473648]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001129477.1 GART gene product H. sapiens 100.0 1009
XP_003319102.1 PREDICTED: trifunctional purine biosynthetic protein adenosine-3 isoform 1 P. troglodytes 99.9 1009
NP_034386.2 Gart gene product M. musculus 90.2 1009
NP_001093352.1 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase X. laevis 81.9 436
NP_571692.1 gart gene product D. rerio 73.9 1015
XP_956400.1 hypothetical protein NCU00177 N. crassa 54.4 769
NP_523497.2 adenosine 3, isoform A D. melanogaster 53.0 1344
NP_011280.1 bifunctional aminoimidazole ribotide synthase/glycinamide ribotide synthase S. cerevisiae 52.9 794
XP_001695161.1 predicted protein C. reinhardtii 51.5 423
NP_509122.2 Protein F38B6.4 C. elegans 48.8 968
NP_172454.1 phosphoribosylamine--glycine ligase A. thaliana 48.8 426
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
NP_001162513.1 trifunctional purine biosynthetic protein adenosine-3 P. anubis 98.7 1009
XP_001093303.2 PREDICTED: trifunctional purine biosynthetic protein adenosine-3 M. mulatta 98.0 1066

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; uncharacterized tissue; mixed; embryonic tissue; eye; liver; lymph node; thymus; skin; lung; kidney; intestine; mammary gland; uterus; placenta; vascular; bone; bone marrow; mouth; pancreas; muscle; cervix; thyroid; connective tissue; spleen; lymph; umbilical cord; adrenal gland; trachea; stomach; blood; bladder; salivary gland; ascites; ovary; heart; prostate; pharynx; pituitary gland; ear; amniotic fluid; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.11
UniSTS entry: GDB:192321
UniSTS entry: Chr 21 REN85511
UniSTS entry: Chr 21 REN85512
UniSTS entry: Chr 21 GDB:185160
UniSTS entry: Chr 21 D21S1825 [Map Viewer]
UniSTS entry: Chr 21 SHGC-87570 [Map Viewer]
UniSTS entry: Chr 21 STS-D32051
UniSTS entry: Chr 21 REN85592
UniSTS entry: Chr 21 REN85590
UniSTS entry: Chr 21 REN85591
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

NM_175085.2 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 2, mRNA PA
BX648124.1 Homo sapiens mRNA; cDNA DKFZp686F0640 (from clone DKFZp686F0640) PA
NM_000819.4 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA PA
BC068438.1 Homo sapiens cDNA clone IMAGE:4825064, containing frame-shift errors PA
AB208785.1 Homo sapiens mRNA for phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase isoform 1 variant protein P
BC093641.1 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, mRNA (cDNA clone IMAGE:7939486), complete cds P
BC101565.1 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, transcript variant 2, mRNA (cDNA clone IMAGE:8069071), complete cds P
BC107712.1 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, mRNA (cDNA clone MGC:104169 IMAGE:6701741), complete cds PA
M32082.1 Human phosphoribosylglycinamide formyltransferase (PGFT) mRNA, 3' end P
AK292897.1 Homo sapiens cDNA FLJ78616 complete cds, highly similar to Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 1, mRNA PA
AK292560.1 Homo sapiens cDNA FLJ75146 complete cds, highly similar to Human mRNA for GARS-AIRS-GART P
AK295980.1 Homo sapiens cDNA FLJ51866 complete cds, highly similar to Trifunctional purine biosynthetic protein adenosine-3 P
X54199.1 Human mRNA for GARS-AIRS-GART PA
NM_001136006.1 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 4, mRNA PA
NM_001136005.1 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 3, mRNA PA
BC038958.1 Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, mRNA (cDNA clone IMAGE:5789599), complete cds PA
D32051.1 Homo sapiens mRNA for GARS protein, complete cds P
AF008655.1 Homo sapiens GARS-AIRS-GART mRNA, partial cds P

EST sequences (10 of 685) [Show all sequences]

R14198.1 Clone IMAGE:28596 brain 5' read P
R16597.1 Clone IMAGE:129587 mixed 5' read
AA928426.1 Clone IMAGE:1560067 intestine 3' read PA
AI033239.1 Clone IMAGE:1654857 mixed 3' read
AI040066.1 Clone IMAGE:1657652 embryonic tissue 3' read P
AI056638.1 Clone IMAGE:1675709 mixed 3' read A
AI076269.1 Clone IMAGE:1672810 mixed 3' read P
R21382.1 Clone IMAGE:36299 brain 5' read P
AA909822.1 Clone IMAGE:1455124 ovary 3' read P
AI144165.1 Clone IMAGE:1707405 heart 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help