> Talin 1 (TLN1)
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UGID:686173     UniGene Hs.471014     Homo sapiens (human)   TLN1
Talin 1 (TLN1)

Human protein-coding gene TLN1. Represented by 1080 ESTs from 387 cDNA libraries. Corresponds to reference sequence NM_006289.3. [UniGene 686173 - Hs.471014]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006280.3 TLN1 gene product H. sapiens 100.0 2540
XP_003312119.1 PREDICTED: LOW QUALITY PROTEIN: talin-1 P. troglodytes 100.0 2547
XP_003911573.1 PREDICTED: talin-1 P. anubis 99.9 2540
XP_003639438.1 PREDICTED: talin-1-like C. lupus familiaris 99.8 2540
XP_002708050.1 PREDICTED: rhea-like O. cuniculus 99.7 2541
XP_001504543.2 PREDICTED: talin-1 E. caballus 99.6 2540
XP_001084941.2 PREDICTED: talin-1 M. mulatta 99.6 2427
NP_001192357.1 talin-1 B. taurus 99.6 2540
NP_035732.2 Tln1 gene product M. musculus 99.5 2540
NP_001106899.1 talin 2 X. laevis 96.4 251
NP_001009560.1 tln1 gene product D. rerio 88.0 2537
NP_001021818.1 Protein Y71G12B.11, isoform b C. elegans 57.0 472
NP_648238.1 rhea, isoform F D. melanogaster 55.1 2628
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
NP_001034114.2 talin-1 R. norvegicus 99.5 2540
XP_003353615.1 PREDICTED: LOW QUALITY PROTEIN: talin-1 S. scrofa 99.3 2543

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; skin; lung; brain; uncharacterized tissue; uterus; embryonic tissue; eye; pancreas; placenta; blood; lymph node; mammary gland; mouth; adipose tissue; thyroid; lymph; spleen; mixed; prostate; kidney; liver; umbilical cord; ovary; muscle; pituitary gland; larynx; testis; amniotic fluid; connective tissue; cervix; thymus; stomach; adrenal gland; vascular; bone; bone marrow; tonsil; epididymis; salivary gland; heart; nerve; ganglia; pharynx; bladder; spinal cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9p13
UniSTS entry: Chr 9 WI-14287 [Map Viewer]
UniSTS entry: Chr 9 TLN1
UniSTS entry: Chr 9 D9S2129E
UniSTS entry: Chr 1 G35510
UniSTS entry: Chr 1 RH80030
UniSTS entry: Chr 1 D15S1477
UniSTS entry: Chr 1 D11S2875
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

BC042923.1 Homo sapiens talin 1, mRNA (cDNA clone MGC:45981 IMAGE:5576203), complete cds PA
AF078828.1 Homo sapiens talin mRNA, complete cds P
AB028950.2 Homo sapiens mRNA for KIAA1027 protein, partial cds P
NM_006289.3 Homo sapiens talin 1 (TLN1), mRNA PA
AK001026.1 Homo sapiens cDNA FLJ10164 fis, clone HEMBA1003581, moderately similar to TALIN
AF177198.1 Homo sapiens talin mRNA, complete cds P
AF113217.1 Homo sapiens MSTP037 mRNA, complete cds A
BC020881.1 Homo sapiens talin 1, mRNA (cDNA clone IMAGE:4615125), with apparent retained intron PA
AF001392.1 Homo sapiens talin-related protein mRNA, partial cds P
Z50170.1 H.sapiens partial mRNA; single read (clone A3351) P

EST sequences (10 of 1080) [Show all sequences]

AA954917.1 Clone IMAGE:1574412 kidney 3' read
R17242.1 Clone IMAGE:32053 brain 5' read P
R18442.1 Clone IMAGE:30029 brain 5' read
AA947238.1 Clone IMAGE:1560350 intestine 3' read A
AI042398.1 Clone IMAGE:1665002 skin 3' read A
CB045708.1 Clone IMAGE:3218227 intestine 3' read A
CB045709.1 Clone IMAGE:3218227 intestine 5' read P
AI148297.1 Clone IMAGE:1697846 uterus 3' read P
AI206705.1 Clone IMAGE:1754474 testis 3' read A
AI250778.1 Clone IMAGE:1858590 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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