> Excision repair cross-complementing rodent repair deficiency, complementation group 3 (ERCC3)
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UGID:685031     UniGene Hs.469872     Homo sapiens (human)   ERCC3 Order cDNA clone, Links
Excision repair cross-complementing rodent repair deficiency, complementation group 3 (ERCC3)

Human protein-coding gene ERCC3. Represented by 757 ESTs from 271 cDNA libraries. Corresponds to reference sequence NM_000122.1. [UniGene 685031 - Hs.469872]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001086722.1 PREDICTED: TFIIH basal transcription factor complex helicase XPB subunit isoform 2 M. mulatta 100.0 781
XP_003909307.1 PREDICTED: TFIIH basal transcription factor complex helicase XPB subunit isoform 1 P. anubis 100.0 781
NP_000113.1 ERCC3 gene product H. sapiens 100.0 781
XP_525907.3 PREDICTED: TFIIH basal transcription factor complex helicase XPB subunit P. troglodytes 99.7 750
XP_002712461.1 PREDICTED: excision repair cross-complementing rodent repair deficiency, complementation group 3 O. cuniculus 99.6 781
NP_598419.1 TFIIH basal transcription factor complex helicase XPB subunit M. musculus 98.7 782
NP_963876.1 ercc3 gene product D. rerio 95.7 781
NP_001137931.1 haywire, isoform B D. melanogaster 79.8 794
NP_499487.1 Protein Y66D12A.15 C. elegans 74.8 787
NP_012123.1 Ssl2p S. cerevisiae 66.7 772
NP_568591.1 DNA repair helicase XPB2 A. thaliana 65.2 751
XP_957329.1 DNA repair helicase RAD25 N. crassa 61.3 732
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_004004543.1 PREDICTED: TFIIH basal transcription factor complex helicase XPB subunit O. aries 99.4 781
XP_003133336.2 PREDICTED: TFIIH basal transcription factor complex helicase XPB subunit-like S. scrofa 99.2 781

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; kidney; uterus; prostate; mouth; thyroid; adrenal gland; bladder; cervix; spleen; muscle; umbilical cord; ovary; thymus; lung; blood; embryonic tissue; stomach; eye; pancreas; intestine; skin; mixed; larynx; salivary gland; mammary gland; esophagus; placenta; trachea; tonsil; ascites; connective tissue; liver; heart; vascular; lymph node; bone marrow; adipose tissue; pituitary gland; pharynx; nerve; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q21
UniSTS entry: Chr 2 D2S2558 [Map Viewer]
UniSTS entry: Chr 2 RH69120 [Map Viewer]
UniSTS entry: Chr 2 RH48443
UniSTS entry: Chr 1 GDB:631802
UniSTS entry: Chr 15 Rnu2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AK127469.1 Homo sapiens cDNA FLJ45561 fis, clone BRTHA3003736, highly similar to TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) P
AK126697.1 Homo sapiens cDNA FLJ44743 fis, clone BRACE3028214, moderately similar to TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) P
NM_000122.1 Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 3 (ERCC3), mRNA P
M31899.1 Human DNA repair helicase (ERCC3) mRNA, complete cds P
AK222465.1 Homo sapiens mRNA for excision repair cross-complementing rodent repair deficiency, complementation group 3 variant, clone: adKA02463 PA
BC008820.2 Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing), mRNA (cDNA clone MGC:10371 IMAGE:3958781), complete cds PA
AK290474.1 Homo sapiens cDNA FLJ76102 complete cds, highly similar to Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) (ERCC3), mRNA P
AK307338.1 Homo sapiens cDNA, FLJ97286 P
AK309405.1 Homo sapiens cDNA, FLJ99446 P
AK095557.1 Homo sapiens cDNA FLJ38238 fis, clone FCBBF2005733, highly similar to TFIIH basal transcription factor complexhelicase XPB subunit (EC 3.6.1.-) P
AK091500.1 Homo sapiens cDNA FLJ34181 fis, clone FCBBF3016667, highly similar to TFIIH basal transcription factor complexhelicase XPB subunit (EC 3.6.1.-) P
AK300250.1 Homo sapiens cDNA FLJ59006 complete cds, highly similar to TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) P

EST sequences (10 of 757) [Show all sequences]

AA865849.1 Clone IMAGE:1456867 kidney 3' read A
AA969059.1 Clone IMAGE:1579623 mixed 3' read A
R16755.1 Clone IMAGE:128773 mixed 3' read A
AI022059.1 Clone IMAGE:1655018 mixed 3' read P
AI076193.1 Clone IMAGE:1674110 mixed 3' read PA
CB048024.1 Clone IMAGE:3270567 prostate 5' read P
CB048023.1 Clone IMAGE:3270567 prostate 3' read PA
CB053737.1 Clone IMAGE:3290849 uncharacterized tissue 5' read P
BX090398.1 Clone IMAGp998E03314_;_IMAGE:173162 brain P
AI222871.1 Clone IMAGE:1925463 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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