> BUB1 mitotic checkpoint serine/threonine kinase (BUB1)
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UGID:684808     UniGene Hs.469649     Homo sapiens (human)   BUB1 Order cDNA clone, Links
BUB1 mitotic checkpoint serine/threonine kinase (BUB1)

Human protein-coding gene BUB1. Represented by 353 ESTs from 135 cDNA libraries. Corresponds to reference sequence NM_004336.3. [UniGene 684808 - Hs.469649]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004327.1 BUB1 gene product H. sapiens 100.0 1084
XP_001142040.1 PREDICTED: mitotic checkpoint serine/threonine-protein kinase BUB1 isoform 1 P. troglodytes 99.8 1084
NP_033902.2 Bub1 gene product M. musculus 81.5 1057
XP_002665685.2 PREDICTED: mitotic checkpoint serine/threonine-protein kinase BUB1 D. rerio 60.1 466
NP_001082116.1 BUB1 budding uninhibited by benzimidazoles 1 homolog X. laevis 56.5 1136
Other hits (2 of 24) [Show all]SpeciesId(%)Len(aa)
XP_003909164.1 PREDICTED: mitotic checkpoint serine/threonine-protein kinase BUB1 isoform 1 P. anubis 98.5 1084
XP_002808098.1 PREDICTED: LOW QUALITY PROTEIN: mitotic checkpoint serine/threonine-protein kinase BUB1-like M. mulatta 98.2 1084

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; embryonic tissue; thymus; brain; uncharacterized tissue; kidney; mixed; placenta; esophagus; bladder; liver; lymph; lymph node; pharynx; lung; connective tissue; vascular; bone marrow; mammary gland; blood; intestine; pancreas; skin; uterus; muscle; trachea; adrenal gland; prostate; ascites; mouth; ovary; cervix; eye; stomach; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q14
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_004336.3 Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase (BUB1), mRNA PA
AK023540.1 Homo sapiens cDNA FLJ13478 fis, clone PLACE1003709, highly similar to Homo sapiens mitotic checkpoint kinase Bub1 (BUB1) mRNA P
AK225317.1 Homo sapiens mRNA for BUB1 budding uninhibited by benzimidazoles 1 homolog, clone: HEP05253 PA
AK291221.1 Homo sapiens cDNA FLJ76827 complete cds, highly similar to Homo sapiens BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1), mRNA PA
BC028201.1 Homo sapiens budding uninhibited by benzimidazoles 1 homolog (yeast), mRNA (cDNA clone MGC:39991 IMAGE:5205385), complete cds PA
AK302418.1 Homo sapiens cDNA FLJ53397 complete cds, highly similar to Mitotic checkpoint serine/threonine-proteinkinase BUB1 (EC 2.7.11.1) P
BC017038.1 Homo sapiens budding uninhibited by benzimidazoles 1 homolog (yeast), mRNA (cDNA clone IMAGE:3914054), partial cds PA
AF011387.1 Homo sapiens putative mitotic checkpoint protein kinase (HsBUB1) mRNA, partial cds P
AF043294.2 Homo sapiens putative mitotic checkpoint kinase mRNA, complete cds PA
AF047471.1 Homo sapiens mitotic checkpoint protein kinase (BUB1) mRNA, complete cds PA
AF053305.1 Homo sapiens mitotic checkpoint kinase Bub1 (BUB1) mRNA, complete cds PA
AF046078.1 Homo sapiens protein kinase (BUB1) mRNA, complete cds PA

EST sequences (10 of 353) [Show all sequences]

AA947532.1 Clone IMAGE:1374902 ovary
AA947533.1 Clone IMAGE:1374904 ovary
AI123198.1 Clone IMAGE:1566409 mixed 3' read
BX101106.1 Clone IMAGp998E161924_;_IMAGE:781047 testis PA
AI184582.1 Clone IMAGE:1733871 testis 3' read PA
AI204517.1 Clone IMAGE:1754049 testis 3' read A
CB148130.1 Clone L16HLK3-2-D02 liver 5' read P
CB159765.1 Clone L18POOL1n1-26-F12 liver 5' read P
CB162842.1 Clone L18POOL1n1-41-A11 liver 5' read P
CB111552.1 Clone L5HLK1-19-H03 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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