> Cell division cycle 42 (CDC42)
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UGID:682796     UniGene Hs.467637     Homo sapiens (human)   CDC42 Order cDNA clone, Links
Cell division cycle 42 (CDC42)

Human protein-coding gene CDC42. Represented by 1412 ESTs from 410 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 682796 - Hs.467637]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003949365.1 PREDICTED: cell division control protein 42 homolog P. troglodytes 100.0 235
NP_001230698.1 Cdc42 gene product M. musculus 100.0 190
NP_741991.3 Cdc42 gene product R. norvegicus 100.0 190
XP_001366319.1 PREDICTED: cell division control protein 42 homolog isoform 2 M. domestica 100.0 190
XP_003973794.1 PREDICTED: cell division control protein 42 homolog isoform 1 T. rubripes 100.0 190
XP_002194369.1 PREDICTED: cell division control protein 42 homolog isoform 1 T. guttata 100.0 190
NP_001018130.1 cdc42 gene product D. rerio 100.0 190
NP_001188177.1 cell division control protein 42 homolog I. punctatus 100.0 190
XP_004069087.1 PREDICTED: cell division control protein 42 homolog isoform 1 O. latipes 100.0 190
XP_003442835.1 PREDICTED: cell division control protein 42 homolog isoform 2 O. niloticus 100.0 190
NP_001079368.1 cell division cycle 42 (GTP binding protein, 25kDa) X. laevis 100.0 190
NP_001008027.1 cdc42 gene product X. tropicalis 100.0 190
NP_990379.1 CDC42 gene product G. gallus 100.0 190
XP_003212396.1 PREDICTED: cell division control protein 42 homolog M. gallopavo 100.0 190
XP_001100274.1 PREDICTED: cell division control protein 42 homolog isoform 5 M. mulatta 100.0 190
XP_003891332.1 PREDICTED: cell division control protein 42 homolog isoform 1 P. anubis 100.0 190
NP_426359.1 CDC42 gene product H. sapiens 100.0 190
NP_001003254.1 CDC42 gene product C. lupus familiaris 100.0 190
XP_003364489.1 PREDICTED: cell division control protein 42 homolog E. caballus 100.0 190
NP_001072148.1 CDC42 gene product S. scrofa 100.0 190
NP_001039797.1 CDC42 gene product B. taurus 100.0 190
XP_004005194.1 PREDICTED: cell division control protein 42 homolog isoform 2 O. aries 100.0 190
XP_002716038.1 PREDICTED: cell division cycle 42 isoform 2 O. cuniculus 100.0 190
XP_001516353.2 PREDICTED: cell division control protein 42 homolog, partial O. anatinus 100.0 171
NP_523414.1 Cdc42, isoform A D. melanogaster 98.4 190
NP_495598.1 Protein CDC-42 C. elegans 95.8 190
XP_957345.2 cell division control protein 42 N. crassa 90.8 194
NP_013330.1 Cdc42p S. cerevisiae 88.5 190
NP_195228.1 Rac-like GTP-binding protein ARAC3 A. thaliana 64.1 197
Other hits (2 of 43) [Show all]SpeciesId(%)Len(aa)
XP_003393447.1 PREDICTED: cdc42 homolog B. terrestris 98.4 190
XP_001629535.1 predicted protein N. vectensis 98.4 190

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; lung; mixed; blood; kidney; uncharacterized tissue; testis; skin; pancreas; prostate; intestine; vascular; mammary gland; connective tissue; heart; ascites; spleen; placenta; embryonic tissue; esophagus; pineal gland; larynx; thyroid; eye; liver; thymus; bladder; pharynx; bone marrow; stomach; parathyroid; cervix; lymph node; muscle; bone; mouth; trachea; ovary; adipose tissue; ear; pituitary gland; nerve; umbilical cord; adrenal gland; salivary gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p36.1
UniSTS entry: Chr 8 CDC42
UniSTS entry: Chr 1 G22163
UniSTS entry: Chr 1 G15855
UniSTS entry: Chr 1 SHGC-74349 [Map Viewer]
UniSTS entry: Chr 5 SHGC-12429
UniSTS entry: Chr 1 G34846
UniSTS entry: Chr 1 RH69132
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 7 CDC42_1530
UniSTS entry: Chr 1 UniSTS:224478
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AL121734.1 Isoform of human GTP-binding protein G25K P
AL121735.1 Isoform of human GTP-binding protein G25K P
NM_001791.3 Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA PA
M35543.1 Human GTP-binding protein (G25K) mRNA, complete cds P
M57298.1 Human GTP-binding protein G25K mRNA, complete cds P
NM_001039802.1 Homo sapiens cell division cycle 42 (CDC42), transcript variant 3, mRNA PA
BC002711.2 Homo sapiens cell division cycle 42 (GTP binding protein, 25kDa), mRNA (cDNA clone MGC:3497 IMAGE:3626647), complete cds PA
BC003682.1 Homo sapiens cell division cycle 42 (GTP binding protein, 25kDa), mRNA (cDNA clone MGC:5044 IMAGE:3457085), complete cds PA
NM_044472.2 Homo sapiens cell division cycle 42 (CDC42), transcript variant 2, mRNA PA
BC018266.1 Homo sapiens cell division cycle 42 (GTP binding protein, 25kDa), mRNA (cDNA clone MGC:17253 IMAGE:3449526), complete cds PA
AK311375.1 Homo sapiens cDNA, FLJ18417 P
AF498963.1 Homo sapiens small GTP binding protein CDC42 placental isoform (CDC42) mRNA, complete cds P
AF498962.1 Homo sapiens small GTP binding protein CDC42 (CDC42) mRNA, complete cds P
AK297465.1 Homo sapiens cDNA FLJ55107 complete cds, highly similar to Cell division control protein 42 homolog P
AK303994.1 Homo sapiens cDNA FLJ54776 complete cds, highly similar to Cell division control protein 42 homolog P
BC018622.1 Homo sapiens cDNA clone IMAGE:5015027 A
AL121737.1 Isoform of human GTP-binding protein G25K P
AL121736.1 Isoform of human GTP-binding protein G25K P
AK316449.1 Homo sapiens cDNA, FLJ79348 complete cds, highly similar to Cell division control protein 42 homolog P

EST sequences (10 of 1412) [Show all sequences]

AA970966.1 Clone IMAGE:1575245 kidney 3' read
R15867.1 Clone IMAGE:53015 brain 3' read A
R15868.1 Clone IMAGE:53015 brain 5' read P
AA973369.1 Clone IMAGE:1568931 lung 3' read
R16049.1 Clone IMAGE:53070 brain 3' read A
R16050.1 Clone IMAGE:53070 brain 5' read P
AA987653.1 Clone IMAGE:1604341 lung 3' read
AA988132.1 Clone IMAGE:1604647 lung 3' read A
AA903625.1 Clone IMAGE:1518283 uncharacterized tissue 3' read A
AA906805.1 Clone IMAGE:1519569 uncharacterized tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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