> Protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A)
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UGID:682351     UniGene Hs.467192     Homo sapiens (human)   PPP2R1A Order cDNA clone, Links
Protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A)

Human protein-coding gene PPP2R1A. Represented by 3967 ESTs from 517 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 682351 - Hs.467192]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_058587.1 Ppp2r1a gene product M. musculus 100.0 588
NP_476481.1 Ppp2r1a gene product R. norvegicus 100.0 588
XP_001116604.1 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like isoform 9 M. mulatta 100.0 588
XP_003916090.1 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform P. anubis 100.0 588
XP_001174546.1 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform 10 P. troglodytes 100.0 588
NP_055040.2 PPP2R1A gene product H. sapiens 100.0 588
XP_850993.1 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform 2 C. lupus familiaris 100.0 588
NP_999189.1 PPP2R1A gene product S. scrofa 100.0 588
XP_004015455.1 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like O. aries 100.0 558
NP_001032554.1 PPP2R1A gene product B. taurus 99.8 588
XP_001378737.1 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like M. domestica 99.7 587
NP_001080135.1 protein phosphatase 2, regulatory subunit A, alpha X. laevis 98.5 588
NP_001005590.1 ppp2r1b gene product D. rerio 93.5 588
NP_001027225.1 protein phosphatase 2A at 29B, isoform C D. melanogaster 82.6 590
NP_498162.2 Protein PAA-1 C. elegans 73.5 588
NP_189208.1 protein phosphatase 2A subunit A2 A. thaliana 69.2 582
XP_001728513.1 protein phosphatase PP2A regulatory subunit A N. crassa 63.6 619
XP_001697300.1 protein phosphatase 2A regulatory subunit C. reinhardtii 61.8 583
NP_009386.1 Tpd3p S. cerevisiae 54.7 633
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_001496310.2 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like isoform 1 E. caballus 99.2 656
XP_003225135.1 PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like A. carolinensis 99.2 588

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; uncharacterized tissue; testis; skin; uterus; intestine; lung; connective tissue; thymus; spleen; adrenal gland; embryonic tissue; prostate; placenta; eye; vascular; mammary gland; blood; pancreas; ovary; heart; mouth; stomach; muscle; lymph; liver; mixed; ascites; thyroid; trachea; cervix; bone; salivary gland; lymph node; umbilical cord; bone marrow; adipose tissue; bladder; larynx; tonsil; esophagus; pituitary gland; nerve; ganglia; pineal gland; epididymis; peritoneum; parathyroid; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.41
UniSTS entry: Ppp2r1a
UniSTS entry: BF390652
UniSTS entry: SHGC-8081
UniSTS entry: PPP2R1A
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

AK130000.1 Homo sapiens cDNA FLJ26490 fis, clone KDN05953, highly similar to Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform P
CR450340.1 Homo sapiens full open reading frame cDNA clone RZPDo834D1214D for gene PPP2R1A, protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; complete cds; without stopcodon P
NM_014225.5 Homo sapiens protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A), transcript variant 1, mRNA PA
BC001537.2 Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform, mRNA (cDNA clone MGC:786 IMAGE:2987938), complete cds PA
AK291932.1 Homo sapiens cDNA FLJ78455 complete cds, highly similar to Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA P
AK290593.1 Homo sapiens cDNA FLJ77680 complete cds, highly similar to Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA PA
AK315700.1 Homo sapiens cDNA, FLJ96799, Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA P
AK307743.1 Homo sapiens cDNA, FLJ97691 P
AK091387.1 Homo sapiens cDNA FLJ34068 fis, clone FCBBF3001918, highly similar to SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 65 KDA REGULATORY SUBUNIT A, ALPHA ISOFORM P
AK090488.1 Homo sapiens cDNA FLJ33169 fis, clone ADRGL2000384, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform P
AK293174.1 Homo sapiens cDNA FLJ53296 complete cds, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform P
AK293493.1 Homo sapiens cDNA FLJ56053 complete cds, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform P
AK299012.1 Homo sapiens cDNA FLJ56133 complete cds, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform PA
AK303934.1 Homo sapiens cDNA FLJ59603 complete cds, highly similar to Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform P
BC026733.1 Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform, mRNA (cDNA clone IMAGE:5111467) PA
NR_033500.1 Homo sapiens protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A), transcript variant 2, non-coding RNA PA

EST sequences (10 of 3967) [Show all sequences]

AA992320.1 Clone IMAGE:1620522 testis 3' read A
AA903754.1 Clone IMAGE:1518721 uncharacterized tissue 3' read A
T26513.1 Clone LLAB285B2 brain 3' read A
T26514.1 Clone LLAB285B2 brain 5' read P
T26515.1 Clone LLAB285B2R brain P
AI080558.1 Clone IMAGE:1680051 skin 3' read A
AI146917.1 Clone IMAGE:1666742 skin 3' read A
AI266482.1 Clone IMAGE:1891811 placenta 3' read A
AI267873.1 Clone IMAGE:1909222 lung 3' read P
CB124894.1 Clone L5HLK1s1-6-A03 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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