> Adaptor-related protein complex 2, alpha 1 subunit (AP2A1)
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UGID:682284     UniGene Hs.467125     Homo sapiens (human)   AP2A1 Order cDNA clone, Links
Adaptor-related protein complex 2, alpha 1 subunit (AP2A1)

Human protein-coding gene AP2A1. Represented by 387 ESTs from 165 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 682284 - Hs.467125]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055018.2 AP2A1 gene product H. sapiens 100.0 976
XP_003915970.1 PREDICTED: AP-2 complex subunit alpha-1 isoform 2 P. anubis 99.9 976
XP_001115452.1 PREDICTED: AP-2 complex subunit alpha-1-like isoform 2 M. mulatta 99.9 954
XP_541490.4 PREDICTED: AP-2 complex subunit alpha-1 isoform 3 C. lupus familiaris 99.8 977
XP_003127386.1 PREDICTED: AP-2 complex subunit alpha-1 isoform 1 S. scrofa 99.7 977
XP_001917381.2 PREDICTED: LOW QUALITY PROTEIN: AP-2 complex subunit alpha-1 E. caballus 99.6 965
NP_031484.1 Ap2a1 gene product M. musculus 99.5 976
XP_001922441.2 PREDICTED: AP-2 complex subunit alpha-2-like isoform 2 D. rerio 92.2 958
NP_001089303.1 adaptor-related protein complex 2, alpha 2 subunit X. laevis 89.8 938
NP_476819.2 alpha-Adaptin, isoform A D. melanogaster 80.0 936
NP_509572.1 Protein APA-2 C. elegans 78.0 924
XP_956726.1 hypothetical protein NCU03440 N. crassa 57.7 610
NP_197670.1 AP-2 complex subunit alpha-2 A. thaliana 53.6 627
XP_001690919.1 alpha-adaptin C. reinhardtii 52.8 212
Other hits (2 of 49) [Show all]SpeciesId(%)Len(aa)
NP_001100981.1 AP-2 complex subunit alpha-1 R. norvegicus 99.5 976
XP_002724093.1 PREDICTED: adaptor-related protein complex 2, alpha 1 subunit O. cuniculus 99.3 960

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; tonsil; larynx; parathyroid; ascites; salivary gland; ovary; testis; bladder; skin; stomach; thymus; uncharacterized tissue; intestine; adrenal gland; eye; lung; pancreas; placenta; mammary gland; liver; lymph; thyroid; uterus; mixed; prostate; cervix; blood; kidney; muscle; vascular; adipose tissue; spleen; bone marrow; heart; pituitary gland; ganglia; bone; connective tissue; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.33
UniSTS entry: Chr 19 MARC_13831-13832:1006881711:1
UniSTS entry: Chr 19 STS-AA031950 [Map Viewer]
UniSTS entry: Chr 19 RH102233
UniSTS entry: Chr 19 MARC_23449-23450:1027106382:1
UniSTS entry: Chr 19 RH75669
UniSTS entry: Chr 19 Ap2a1
UniSTS entry: Chr 1 D10S16
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK124343.1 Homo sapiens cDNA FLJ42352 fis, clone UTERU2006115, highly similar to ALPHA-ADAPTIN A P
AL136925.1 Homo sapiens mRNA; cDNA DKFZp586H1320 (from clone DKFZp586H1320) PA
BC111754.1 Homo sapiens cDNA clone IMAGE:40008106 P
BC014214.2 Homo sapiens adaptor-related protein complex 2, alpha 1 subunit, mRNA (cDNA clone MGC:20679 IMAGE:4111165), complete cds PA
NM_130787.2 Homo sapiens adaptor-related protein complex 2, alpha 1 subunit (AP2A1), transcript variant 2, mRNA P
NM_014203.2 Homo sapiens adaptor-related protein complex 2, alpha 1 subunit (AP2A1), transcript variant 1, mRNA P
AK096757.1 Homo sapiens cDNA FLJ39438 fis, clone PROST2005076
AK094317.1 Homo sapiens cDNA FLJ36998 fis, clone BRACE2007295, highly similar to ALPHA-ADAPTIN A P
AK090661.1 Homo sapiens cDNA FLJ33342 fis, clone BRACE2002834, moderately similar to ALPHA-ADAPTIN A P
AK302005.1 Homo sapiens cDNA FLJ61453 complete cds, highly similar to Adapter-relatedprotein complex 2 alpha- 1 subunit P

EST sequences (10 of 387) [Show all sequences]

AA974267.1 Clone IMAGE:1586301 uncharacterized tissue 3' read A
AA985102.1 Clone IMAGE:1616201 brain 3' read
AA993745.1 Clone IMAGE:1620019 testis 3' read PA
AA995684.1 Clone IMAGE:1606386 kidney 3' read
CB044192.1 Clone IMAGE:3217454 intestine 5' read P
CB045212.1 Clone IMAGE:3218204 intestine 5' read P
CB124131.1 Clone L5HLK1s1-5-H09 liver 5' read P
CB156231.1 Clone B2N807043-9-C01 brain 5' read P
AA833725.1 Clone 1393525 testis 3' read A
R38604.1 Clone IMAGE:26555 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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