> Phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A)
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UGID:681963     UniGene Hs.466804     Homo sapiens (human)   PLA2G2A Order cDNA clone, Links
Phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A)

Human protein-coding gene PLA2G2A. Represented by 328 ESTs from 103 cDNA libraries. EST representation biased toward adult. Corresponds to 4 reference sequences (different isoforms). [UniGene 681963 - Hs.466804]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001155199.1 PLA2G2A gene product H. sapiens 100.0 143
NP_001076000.1 phospholipase A2, membrane associated precursor M. musculus 71.9 145
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_001160344.1 PREDICTED: phospholipase A2, membrane associated isoform 2 P. troglodytes 97.9 143
XP_003891295.1 PREDICTED: phospholipase A2, membrane associated isoform 1 P. anubis 93.8 143

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; connective tissue; liver; intestine; eye; prostate; uncharacterized tissue; stomach; muscle; mammary gland; brain; adipose tissue; mixed; lung; adrenal gland; bone; uterus; testis; heart; vascular; kidney; mouth
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p35
UniSTS entry: Chr 1 SHGC-74294 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

M22430.1 Human RASF-A PLA2 mRNA, complete cds PA
NM_000300.3 Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), transcript variant 1, mRNA PA
CR456865.1 Homo sapiens full open reading frame cDNA clone RZPDo834E0615D for gene PLA2G2A, phospholipase A2, group IIA (platelets, synovial fluid); complete cds, incl. stopcodon P
AY656696.1 Homo sapiens hepatocarcinoma platelet phospholipase A2 mRNA, complete cds P
AY656695.1 Homo sapiens liver platelet phospholipase A2 mRNA, complete cds P
BC005919.1 Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid), mRNA (cDNA clone MGC:14516 IMAGE:4274550), complete cds PA
AK291302.1 Homo sapiens cDNA FLJ75686 complete cds, highly similar to Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), mRNA PA
NM_001161729.1 Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), transcript variant 4, mRNA PA
NM_001161728.1 Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), transcript variant 3, mRNA PA
NM_001161727.1 Homo sapiens phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), transcript variant 2, mRNA PA

EST sequences (10 of 328) [Show all sequences]

R21194.1 Clone IMAGE:130305 placenta 5' read P
R22811.1 Clone IMAGE:130305 placenta 3' read A
AI128751.1 Clone IMAGE:1691432 heart 3' read A
AI149280.1 Clone IMAGE:1715132 placenta 3' read A
AI150776.1 Clone IMAGE:1708837 heart 3' read PA
R24705.1 Clone IMAGE:131967 placenta 5' read
BX098088.1 Clone IMAGp998N13665_;_IMAGE:297804 lung P
AI168206.1 Clone IMAGE:1509300 mixed 3' read A
R25199.1 Clone IMAGE:131967 placenta 3' read
AI186301.1 Clone IMAGE:1724763 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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