> Glucose-6-phosphate isomerase (GPI)
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UGID:681630     UniGene Hs.466471     Homo sapiens (human)   GPI
Glucose-6-phosphate isomerase (GPI)

Human protein-coding gene GPI. Represented by 4121 ESTs from 583 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 681630 - Hs.466471]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001171651.1 GPI gene product H. sapiens 100.0 568
XP_003316332.1 PREDICTED: glucose-6-phosphate isomerase-like, partial P. troglodytes 100.0 289
NP_032181.2 Gpi1 gene product M. musculus 94.4 557
NP_658910.2 gpib gene product D. rerio 85.3 552
NP_001085765.1 glucose-6-phosphate isomerase X. laevis 85.3 552
NP_523663.1 phosphoglucose isomerase, isoform A D. melanogaster 76.6 555
NP_001021837.1 Protein GPI-1, isoform a C. elegans 75.9 550
NP_009755.1 glucose-6-phosphate isomerase S. cerevisiae 65.8 552
XP_962135.1 Glucose-6-phosphate isomerase N. crassa 62.8 557
NP_199088.1 glucose-6-phosphate isomerase A. thaliana 54.0 556
XP_001703279.1 phosphoglucose isomerase C. reinhardtii 52.1 520
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_001110104.1 PREDICTED: glucose-6-phosphate isomerase-like M. mulatta 99.4 312
XP_003919554.1 PREDICTED: LOW QUALITY PROTEIN: glucose-6-phosphate isomerase P. anubis 97.9 339

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; kidney; prostate; intestine; blood; esophagus; bone marrow; testis; uterus; heart; lung; skin; liver; mammary gland; stomach; connective tissue; thymus; ovary; adrenal gland; vascular; eye; pancreas; mouth; lymph; ascites; embryonic tissue; mixed; placenta; thyroid; spleen; cervix; muscle; trachea; umbilical cord; bladder; salivary gland; bone; nerve; lymph node; adipose tissue; tonsil; epididymis; larynx; pineal gland; pharynx; pituitary gland; ganglia; parathyroid; spinal cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.1
UniSTS entry: Chr 19 IB853 [Map Viewer]
UniSTS entry: Chr 19 STS-K03515 [Map Viewer]
UniSTS entry: Chr 19 D19S984 [Map Viewer]
UniSTS entry: Chr 19 D19S630E
UniSTS entry: Chr 19 GPI
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 19 GPI
UniSTS entry: Chr 1 G35510
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

K03515.1 Human neuroleukin mRNA, complete cds P
AK130102.1 Homo sapiens cDNA FLJ26592 fis, clone LNF08050, highly similar to Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) P
AK129884.1 Homo sapiens cDNA FLJ26374 fis, clone HRT06262, highly similar to Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) P
NM_000175.3 Homo sapiens glucose-6-phosphate isomerase (GPI), transcript variant 2, mRNA PA
BC004982.1 Homo sapiens glucose phosphate isomerase, mRNA (cDNA clone MGC:3935 IMAGE:2906270), complete cds P
AK294396.1 Homo sapiens cDNA FLJ56429 complete cds, highly similar to Glucose-6-phosphate isomerase (EC 5.3.1.9) P
AK301103.1 Homo sapiens cDNA FLJ53666 complete cds, highly similar to Glucose-6-phosphate isomerase (EC 5.3.1.9) P
AK293446.1 Homo sapiens cDNA FLJ53303 complete cds, highly similar to Glucose-6-phosphate isomerase (EC 5.3.1.9) P
X16539.1 H.sapiens RNA for neuroleukin gene P
NM_001184722.1 Homo sapiens glucose-6-phosphate isomerase (GPI), transcript variant 1, mRNA PA

EST sequences (10 of 4121) [Show all sequences]

AA968589.1 Clone IMAGE:1578317 mixed 3' read PA
AA993013.1 Clone IMAGE:1622748 embryonic tissue 3' read A
CA976126.1 Clone IMAGE:6202540 nerve 5' read P
AA862873.1 Clone IMAGE:1469803 uncharacterized tissue 3' read A
AA908503.1 Clone IMAGE:1454874 ovary 3' read A
AI124792.1 Clone IMAGE:1539552 brain 3' read P
CB046419.1 Clone IMAGE:3252539 kidney 3' read PA
CB046420.1 Clone IMAGE:3252539 kidney 5' read PA
BX096161.1 Clone IMAGp998L21252_;_IMAGE:158372 mammary gland A
AI183387.1 Clone IMAGE:1732073 heart 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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