> Insulin receptor (INSR)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:680903     UniGene Hs.465744     Homo sapiens (human)   INSR Order cDNA clone, Links
Insulin receptor (INSR)

Human protein-coding gene INSR. Represented by 284 ESTs from 147 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 680903 - Hs.465744]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000199.2 INSR gene product H. sapiens 100.0 1381
NP_034698.2 Insr gene product M. musculus 97.1 1371
NP_001081702.1 insulin receptor precursor X. laevis 78.8 1328
NP_001136144.1 insra gene product D. rerio 76.1 1347
NP_001138093.1 Insulin-like receptor, isoform B D. melanogaster 64.0 344
Other hits (2 of 40) [Show all]SpeciesId(%)Len(aa)
XP_003914827.1 PREDICTED: insulin receptor P. anubis 99.4 1369
XP_001496634.1 PREDICTED: insulin receptor E. caballus 98.1 1348

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; lung; brain; mammary gland; intestine; testis; prostate; eye; mixed; uncharacterized tissue; kidney; thymus; stomach; pancreas; ovary; liver; muscle; lymph node; adrenal gland; parathyroid; pineal gland; bladder; trachea; epididymis; pharynx; thyroid; embryonic tissue; uterus; cervix; mouth; heart; adipose tissue; ascites; spleen; bone; blood; vascular; connective tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3-p13.2
UniSTS entry: Chr 19 RH92589
UniSTS entry: Chr 19 RH93377
UniSTS entry: Chr 19 G07087
UniSTS entry: Chr 19 RH80628
UniSTS entry: Chr 19 SHGC-32871 [Map Viewer]
UniSTS entry: GDB:511368
UniSTS entry: Chr 19 G59704
UniSTS entry: Chr 19 Insr
UniSTS entry: Chr 19 GDB:177257
UniSTS entry: GDB:177221
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC047591.1 Homo sapiens insulin receptor, mRNA (cDNA clone IMAGE:4823710), partial cds PA
NM_000208.2 Homo sapiens insulin receptor (INSR), transcript variant 1, mRNA P
AL365454.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 926491 A
AB208861.1 Homo sapiens mRNA for insulin receptor variant protein P
AK025527.1 Homo sapiens cDNA: FLJ21874 fis, clone HEP02488
M10051.1 Human insulin receptor mRNA, complete cds P
BC117172.1 Homo sapiens insulin receptor, mRNA (cDNA clone MGC:150781 IMAGE:40125723), complete cds P
NM_001079817.1 Homo sapiens insulin receptor (INSR), transcript variant 2, mRNA P
X02160.1 Human mRNA for insulin receptor precursor P
AK300332.1 Homo sapiens cDNA FLJ56779 complete cds, highly similar to Insulin receptor precursor (EC 2.7.10.1) P
M24555.1 Human insulin receptor (INSR) mRNA, partial cds

EST sequences (10 of 284) [Show all sequences]

AA975880.1 Clone IMAGE:1558317 lung 3' read
AA993253.1 Clone IMAGE:1621159 testis 3' read
AI023426.1 Clone IMAGE:1652326 mixed 3' read
R23783.1 Clone IMAGE:131622 placenta 5' read
BX100039.1 Clone IMAGp998A02423_;_IMAGE:214921 mammary gland A
BX091744.1 Clone IMAGp998H19185_;_IMAGE:132546 placenta A
BX093227.1 Clone IMAGp998N191887_;_IMAGE:767058 mixed A
R25897.1 Clone IMAGE:132546 placenta 5' read
R26698.1 Clone IMAGE:132546 placenta 3' read
U31292.1 Clone HFBC-4 brain


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help