> Ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (USP14)
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UGID:679575     UniGene Hs.464416     Homo sapiens (human)   USP14 Order cDNA clone, Links
Ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (USP14)

Human protein-coding gene USP14. Represented by 719 ESTs from 305 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 679575 - Hs.464416]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005142.1 USP14 gene product H. sapiens 100.0 493
XP_001090784.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 14 isoform 2 M. mulatta 100.0 492
XP_003914267.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 14 isoform 1 P. anubis 100.0 492
NP_001038961.1 ubiquitin carboxyl-terminal hydrolase 14 P. troglodytes 100.0 492
NP_067497.2 Usp14 gene product M. musculus 98.4 492
NP_001087872.1 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) X. laevis 91.2 488
NP_956267.1 usp14 gene product D. rerio 87.3 488
NP_609377.1 CG5384, isoform A D. melanogaster 62.6 473
NP_564596.1 ubiquitin carboxyl-terminal hydrolase 6 A. thaliana 54.9 213
NP_497006.1 Protein USP-14 C. elegans 47.6 252
XP_965550.1 hypothetical protein NCU01919 N. crassa 47.5 223
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_001492900.3 PREDICTED: ubiquitin carboxyl-terminal hydrolase 14-like isoform 1 E. caballus 99.4 493
XP_003362211.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 14-like S. scrofa 99.0 496

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; liver; testis; skin; vascular; connective tissue; uterus; lung; embryonic tissue; kidney; prostate; placenta; mixed; pancreas; blood; mammary gland; bladder; adrenal gland; adipose tissue; mouth; bone marrow; intestine; spleen; stomach; thymus; eye; heart; trachea; muscle; lymph node; ascites; ovary; cervix; bone; umbilical cord; esophagus; pituitary gland; lymph; ganglia; parathyroid; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18p11.32
UniSTS entry: Chr 18 A003A48
UniSTS entry: Chr 18 D18S1294 [Map Viewer]
UniSTS entry: Chr 18 D18S898E
UniSTS entry: Chr 18 RH65814
UniSTS entry: Chr 18 D18S1244
UniSTS entry: Chr 18 SHGC-30016 [Map Viewer]
UniSTS entry: Chr 18 RH47243
UniSTS entry: Chr 18 D18S918E
UniSTS entry: Chr 2 RH80953
UniSTS entry: Chr 18 USP14__5036
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BT007183.1 Homo sapiens ubiquitin specific protease 14 (tRNA-guanine transglycosylase) mRNA, complete cds P
NM_005151.3 Homo sapiens ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (USP14), transcript variant 1, mRNA P
U30888.1 Human tRNA-guanine transglycosylase mRNA, complete cds P
NM_001037334.1 Homo sapiens ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (USP14), transcript variant 2, mRNA P
BC003556.1 Homo sapiens ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase), mRNA (cDNA clone MGC:1453 IMAGE:3547183), complete cds PA
AK315438.1 Homo sapiens cDNA, FLJ96494, highly similar to Homo sapiens ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (USP14), mRNA P
AK098497.1 Homo sapiens cDNA FLJ25631 fis, clone STM03742 A
AK297605.1 Homo sapiens cDNA FLJ53450 complete cds, highly similar to Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) PA

EST sequences (10 of 719) [Show all sequences]

AA976101.1 Clone IMAGE:1558446 lung 3' read A
T05557.1 Clone HFBDC28 brain
AA994092.1 Clone IMAGE:1630731 mammary gland 3' read
AI015691.1 Clone IMAGE:1636113 kidney 3' read A
AI033415.1 Clone IMAGE:1655275 mixed 3' read
AI041616.1 Clone IMAGE:1663813 skin 3' read
AI087925.1 Clone IMAGE:1566752 mixed 3' read A
AI127115.1 Clone IMAGE:1708126 heart 3' read
CB046777.1 Clone IMAGE:3253041 kidney 5' read
CB051595.1 Clone IMAGE:3289860 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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