> Phosphogluconate dehydrogenase (PGD)
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UGID:679230     UniGene Hs.464071     Homo sapiens (human)   PGD Order cDNA clone, Links
Phosphogluconate dehydrogenase (PGD)

Human protein-coding gene PGD. Represented by 1322 ESTs from 447 cDNA libraries. Corresponds to reference sequence NM_002631.2. [UniGene 679230 - Hs.464071]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003891136.1 PREDICTED: 6-phosphogluconate dehydrogenase, decarboxylating isoform 1 P. anubis 100.0 482
NP_002622.2 PGD gene product H. sapiens 100.0 482
NP_001074743.1 Pgd gene product M. musculus 96.9 482
NP_998717.1 pgd gene product D. rerio 90.7 482
NP_001083291.1 6-phosphogluconate dehydrogenase, decarboxylating X. laevis 89.0 481
NP_476860.2 phosphogluconate dehydrogenase, isoform A D. melanogaster 75.6 479
NP_501998.1 Protein T25B9.9 C. elegans 73.5 483
XP_964959.1 6-phosphogluconate dehydrogenase N. crassa 72.7 519
NP_012053.3 phosphogluconate dehydrogenase (decarboxylating) GND1 S. cerevisiae 71.4 488
NP_186885.1 6-phosphogluconate dehydrogenase A. thaliana 54.6 476
XP_001696881.1 6-phosphogluconate dehydrogenase, decarboxylating C. reinhardtii 54.1 488
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_003307850.1 PREDICTED: 6-phosphogluconate dehydrogenase, decarboxylating P. troglodytes 99.4 481
XP_002808317.1 PREDICTED: LOW QUALITY PROTEIN: kinesin-like protein KIF1B-like M. mulatta 99.2 535

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; uncharacterized tissue; testis; embryonic tissue; blood; eye; placenta; skin; uterus; intestine; liver; mammary gland; mixed; kidney; bone marrow; thymus; esophagus; adrenal gland; ovary; adipose tissue; muscle; umbilical cord; mouth; prostate; epididymis; larynx; connective tissue; vascular; bladder; stomach; ascites; lymph; pancreas; bone; cervix; lymph node; heart; spleen; pharynx; thyroid; trachea; nerve; pituitary gland; salivary gland; tonsil; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p36.22
UniSTS entry: Chr 1 SHGC-74199 [Map Viewer]
UniSTS entry: Chr 1 RH39270
UniSTS entry: Chr 1 RH66785
UniSTS entry: Chr 1 RH70785
UniSTS entry: Chr 1 PGD
UniSTS entry: Chr 18 SHGC-105729
UniSTS entry: Chr 1 D1S1425
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_002631.2 Homo sapiens phosphogluconate dehydrogenase (PGD), mRNA P
U30255.1 Homo sapiens phosphogluconate dehydrogenase (PGDH) mRNA, complete cds P
BC000368.2 Homo sapiens phosphogluconate dehydrogenase, mRNA (cDNA clone MGC:8331 IMAGE:2819330), complete cds PA
AK290404.1 Homo sapiens cDNA FLJ75631 complete cds, highly similar to Homo sapiens phosphogluconate dehydrogenase (PGD), mRNA PA
AK300952.1 Homo sapiens cDNA FLJ52522 complete cds, highly similar to 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) P
AK304423.1 Homo sapiens cDNA FLJ53132 complete cds, highly similar to 6-phosphogluconate dehydrogenase,decarboxylating (EC 1.1.1.44) P
AK298830.1 Homo sapiens cDNA FLJ52518 complete cds, highly similar to 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) P
AK296889.1 Homo sapiens cDNA FLJ52439 complete cds, highly similar to 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) P
AK303898.1 Homo sapiens cDNA FLJ51182 complete cds, highly similar to 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) P

EST sequences (10 of 1322) [Show all sequences]

AA905276.1 Clone IMAGE:1506132 mixed 3' read A
AA977742.1 Clone IMAGE:1589632 kidney 3' read
AA902304.1 Clone IMAGE:1519748 uncharacterized tissue 3' read
AA905053.1 Clone IMAGE:1523313 mixed 3' read A
AI038004.1 Clone IMAGE:1663887 skin 3' read A
AI041909.1 Clone IMAGE:1664569 skin 3' read A
AI090603.1 Clone IMAGE:1692148 heart 3' read A
AI142354.1 Clone IMAGE:1839897 testis 5' read
AI143032.1 Clone IMAGE:1681074 skin 3' read A
AI147347.1 Clone IMAGE:1839897 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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