> CCR4-NOT transcription complex, subunit 1 (CNOT1)
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UGID:676082     UniGene Hs.460923     Homo sapiens (human)   CNOT1
CCR4-NOT transcription complex, subunit 1 (CNOT1)

Human protein-coding gene CNOT1. Represented by 925 ESTs from 361 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 676082 - Hs.460923]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_511007.2 PREDICTED: CCR4-NOT transcription complex subunit 1 isoform 8 P. troglodytes 100.0 2375
NP_057368.3 CNOT1 gene product H. sapiens 100.0 2375
XP_003917028.1 PREDICTED: CCR4-NOT transcription complex subunit 1 P. anubis 100.0 2254
XP_535279.4 PREDICTED: LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 1 isoform 1 C. lupus familiaris 100.0 2375
XP_001495291.1 PREDICTED: CCR4-NOT transcription complex subunit 1 E. caballus 100.0 2375
NP_001192968.1 CCR4-NOT transcription complex subunit 1 B. taurus 100.0 2375
XP_004015089.1 PREDICTED: CCR4-NOT transcription complex subunit 1 O. aries 100.0 2375
XP_002711595.1 PREDICTED: CCR4-NOT transcription complex, subunit 1 O. cuniculus 100.0 2374
XP_001102008.2 PREDICTED: CCR4-NOT transcription complex subunit 1-like M. mulatta 100.0 2339
XP_003127000.1 PREDICTED: CCR4-NOT transcription complex subunit 1 S. scrofa 99.9 2374
NP_835179.1 Cnot1 gene product M. musculus 99.8 2370
NP_001128312.1 CCR4-NOT transcription complex subunit 1 R. norvegicus 99.8 2375
NP_001073420.1 cnot1 gene product D. rerio 95.8 2373
NP_001097243.1 Not1, isoform D D. melanogaster 61.4 2500
XP_001692750.1 component of CCR4-NOT transcriptional regulator complex C. reinhardtii 59.9 430
NP_001184889.1 CCR4-NOT transcription complex subunit 1 A. thaliana 57.9 1714
NP_498516.2 Protein LET-711 C. elegans 57.7 1419
XP_960299.1 hypothetical protein NCU04766 N. crassa 47.3 169
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_003431321.1 PREDICTED: CCR4-NOT transcription complex subunit 1 isoform 2 O. anatinus 99.3 2374
XP_001363026.1 PREDICTED: CCR4-NOT transcription complex subunit 1 isoform 1 M. domestica 99.2 2375

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; embryonic tissue; intestine; lung; stomach; placenta; liver; thymus; uncharacterized tissue; kidney; uterus; mixed; pineal gland; lymph node; spleen; adrenal gland; ear; vascular; adipose tissue; larynx; salivary gland; skin; bladder; mouth; prostate; trachea; muscle; eye; mammary gland; cervix; ovary; bone; lymph; ascites; heart; blood; connective tissue; umbilical cord; thyroid; pancreas; bone marrow; pituitary gland; tonsil; ganglia; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q21
UniSTS entry: Chr 16 D16S2562E
UniSTS entry: Chr 16 A002K05 [Map Viewer]
UniSTS entry: Chr 16 D16S3186
UniSTS entry: Chr 16 D16S2941 [Map Viewer]
UniSTS entry: Chr 16 SHGC-61172
UniSTS entry: Chr 16 RH41889
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

AB023224.2 Homo sapiens mRNA for KIAA1007 protein, partial cds P
BX537840.1 Homo sapiens mRNA; cDNA DKFZp686K24111 (from clone DKFZp686K24111); complete cds PA
AL117492.1 Homo sapiens mRNA; cDNA DKFZp434N241 (from clone DKFZp434N241); partial cds PA
BX647815.1 Homo sapiens mRNA; cDNA DKFZp686L1052 (from clone DKFZp686L1052) PA
NM_206999.2 Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2, mRNA P
NM_016284.4 Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 1, mRNA PA
CR749237.1 Homo sapiens mRNA; cDNA DKFZp686E0722 (from clone DKFZp686E0722) PA
AF110778.1 Homo sapiens adrenal gland protein AD-005 mRNA, complete cds PA
BC000779.2 Homo sapiens CCR4-NOT transcription complex, subunit 1, mRNA (cDNA clone IMAGE:3504586), partial cds PA
EF553522.1 Homo sapiens clone DKFZp686O168 CNOT1 (CNOT1) mRNA, complete cds PA
AK056927.1 Homo sapiens cDNA FLJ32365 fis, clone PUAEN1000161, highly similar to Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2, mRNA P
BC024317.1 Homo sapiens CCR4-NOT transcription complex, subunit 1, mRNA (cDNA clone IMAGE:3913601), partial cds PA
AL833549.1 Homo sapiens mRNA; cDNA DKFZp686N183 (from clone DKFZp686N183) PA
AL832769.1 Homo sapiens mRNA; cDNA DKFZp686A017 (from clone DKFZp686A017) PA
AK300281.1 Homo sapiens cDNA FLJ61392 complete cds, highly similar to Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2, mRNA P
AK302495.1 Homo sapiens cDNA FLJ58490 complete cds, highly similar to Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 1, mRNA P
AK075125.1 Homo sapiens cDNA FLJ90644 fis, clone PLACE1004168 P
BC027969.2 Homo sapiens CCR4-NOT transcription complex, subunit 1, mRNA (cDNA clone IMAGE:5225775) PA
BC011861.2 Homo sapiens CCR4-NOT transcription complex, subunit 1, mRNA (cDNA clone IMAGE:4310622) A
AK301092.1 Homo sapiens cDNA FLJ61738 complete cds, highly similar to Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 1, mRNA P
NR_049763.1 Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 4, non-coding RNA PA
NM_001265612.1 Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 3, mRNA PA
BC040523.1 Homo sapiens CCR4-NOT transcription complex, subunit 1, mRNA (cDNA clone MGC:39516 IMAGE:5266600), complete cds PA

EST sequences (10 of 925) [Show all sequences]

R14268.1 Clone IMAGE:28338 brain 5' read
AA975758.1 Clone IMAGE:1591137 kidney 3' read P
AA987879.1 Clone IMAGE:1592790 kidney 3' read A
AA910865.1 Clone IMAGE:1520741 kidney 3' read P
AA922463.1 Clone IMAGE:1551841 uncharacterized tissue 3' read A
AI076896.1 Clone IMAGE:1672159 uncharacterized tissue 3' read
R21483.1 Clone IMAGE:31370 brain 5' read P
AI089676.1 Clone IMAGE:1686396 brain 3' read P
AI091771.1 Clone IMAGE:1694117 heart 3' read
AI094683.1 Clone IMAGE:1670459 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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