Insulin receptor substrate 4 (IRS4)

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UGID:676031 UniGene Hs.460872 Homo sapiens (human) IRS4

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Insulin receptor substrate 4 (IRS4)

Human protein-coding gene IRS4. Represented by 5 ESTs from 4 cDNA libraries. Corresponds to reference sequence NM_003604.2. [UniGene 676031 - Hs.460872]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_003595.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	IRS4 gene product	H. sapiens	100.0	1256
NP_034702.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Irs4 gene product	M. musculus	77.8	1213
Other hits (2 of 12) [Show all]		Species	Id(%)	Len(aa)
XP_003317671.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: insulin receptor substrate 4, partial	P. troglodytes	98.0	1193
XP_003918178.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin receptor substrate 4	P. anubis	94.7	1250

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources.
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	kidney; brain; adrenal gland; eye

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	X
Map position:	Xq22.3
UniSTS entry:	Chr 1	D1S3695
UniSTS entry:	Chr X	IRS4
UniSTS entry:	Chr X	MARC_37657-37658:1077807976:1
UniSTS entry:	Chr X	RH104228
UniSTS entry:	Chr X	PMC86565P3

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

	NM_003604.2	Homo sapiens insulin receptor substrate 4 (IRS4), mRNA	P
	AF007567.1	Homo sapiens insulin receptor substrate 4 mRNA, complete cds	P

EST sequences (5)

BP246027.1	Clone HKR04804	kidney	5' read	P
BP246872.1	Clone HKR07144	kidney	5' read	P
DA800531.1	Clone OCBBF3004512	brain	5' read	P
AA594716.1	Clone IMAGE:1099538	adrenal gland	3' read	P
AA668250.1	Clone IMAGE:853047	eye	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria