> CREB binding protein (CREBBP)
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UGID:674918     UniGene Hs.459759     Homo sapiens (human)   CREBBP
CREB binding protein (CREBBP)

Human protein-coding gene CREBBP. Represented by 432 ESTs from 222 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 674918 - Hs.459759]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_523285.2 PREDICTED: CREB-binding protein isoform 2 P. troglodytes 100.0 2441
NP_004371.2 CREBBP gene product H. sapiens 100.0 2441
XP_003916506.1 PREDICTED: CREB-binding protein-like P. anubis 99.9 2114
XP_001095225.1 PREDICTED: CREB-binding protein isoform 1 M. mulatta 99.8 2441
NP_001020603.1 Crebbp gene product M. musculus 97.8 2440
NP_001088637.1 CREB binding protein X. laevis 85.1 2427
XP_003198104.1 PREDICTED: CREB-binding protein-like D. rerio 78.2 2387
NP_524642.2 nejire, isoform B D. melanogaster 70.4 1029
NP_001122711.2 Protein CBP-1, isoform c C. elegans 59.6 832
NP_001185015.1 histone acetyltransferase HAC12 A. thaliana 47.4 293
XP_001692031.1 CREB-binding protein C. reinhardtii 45.0 180
Other hits (2 of 44) [Show all]SpeciesId(%)Len(aa)
XP_001499399.3 PREDICTED: CREB-binding protein E. caballus 98.0 2413
NP_596872.3 Crebbp gene product R. norvegicus 97.8 2443

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mammary gland; mixed; lung; stomach; ear; testis; uncharacterized tissue; kidney; placenta; lymph node; muscle; mouth; larynx; pancreas; embryonic tissue; intestine; connective tissue; amniotic fluid; lymph; trachea; liver; skin; thyroid; thymus; eye; blood; prostate; ovary; uterus; pharynx; heart; salivary gland; adrenal gland; bone marrow; adipose tissue; spleen; nerve; bone; bladder
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13.3
UniSTS entry: Chr 16 RH78556
UniSTS entry: Chr 16 b10501s
UniSTS entry: Chr 16 RH65024
UniSTS entry: Chr 16 WI-22537 [Map Viewer]
UniSTS entry: Chr 16 RH66115 [Map Viewer]
UniSTS entry: Chr 16 STS-U89355
UniSTS entry: Chr 16 G64268
UniSTS entry: Chr 16 SHGC-60562 [Map Viewer]
UniSTS entry: Chr 16 RH66116
UniSTS entry: Chr 16 CREBBP_555
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK124320.1 Homo sapiens cDNA FLJ42329 fis, clone TRACH3000558, highly similar to CREB-BINDING PROTEIN P
NM_004380.2 Homo sapiens CREB binding protein (CREBBP), transcript variant 1, mRNA P
AB210043.1 Homo sapiens mRNA for CREBBP variant protein, partial cds, clone: pf01047 P
NM_001079846.1 Homo sapiens CREB binding protein (CREBBP), transcript variant 2, mRNA P
AK304771.1 Homo sapiens cDNA FLJ57039 partial cds, highly similar to CREB-binding protein (EC 2.3.1.48) P
BC036486.1 Homo sapiens CREB binding protein, mRNA (cDNA clone IMAGE:5261283), partial cds PA
U89354.1 Homo sapiens clone cRT0 CREB-binding protein mRNA, partial cds PA
U89355.1 Homo sapiens clone cRT16 CREB-binding protein mRNA, partial cds P
U85962.3 Homo sapiens CREB-binding protein mRNA, complete cds P
U47741.1 Human CREB-binding protein (CBP) mRNA, complete cds PA

EST sequences (10 of 432) [Show all sequences]

AA994887.1 Clone IMAGE:1625535 mixed 3' read PA
R17881.1 Clone IMAGE:31695 brain 5' read P
AI015481.1 Clone IMAGE:1618654 testis 3' read P
AI017248.1 Clone IMAGE:1636274 kidney 3' read A
AA928265.1 Clone IMAGE:1562877 mixed 3' read PA
AI032893.1 Clone IMAGE:1656765 mixed 3' read
AI051629.1 Clone IMAGE:1669280 brain 3' read A
AI089969.1 Clone IMAGE:1687347 brain 3' read
AI125403.1 Clone IMAGE:1737020 testis 3' read A
AI126992.1 Clone IMAGE:1707971 heart 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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