> Chloride channel, voltage-sensitive 7 (CLCN7)
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UGID:674808     UniGene Hs.459649     Homo sapiens (human)   CLCN7
Chloride channel, voltage-sensitive 7 (CLCN7)

Human protein-coding gene CLCN7. Represented by 712 ESTs from 227 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 674808 - Hs.459649]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001159424.1 PREDICTED: H(+)/Cl(-) exchange transporter 7 isoform 1 P. troglodytes 100.0 804
NP_001278.1 CLCN7 gene product H. sapiens 100.0 804
XP_003916380.1 PREDICTED: H(+)/Cl(-) exchange transporter 7 isoform 1 P. anubis 99.8 804
XP_002802404.1 PREDICTED: H(+)/Cl(-) exchange transporter 7-like M. mulatta 99.7 781
NP_036060.1 Clcn7 gene product M. musculus 98.9 802
NP_001085734.1 chloride channel, voltage-sensitive 7 X. laevis 87.2 798
NP_001071005.1 clcn7 gene product D. rerio 84.8 794
NP_506022.1 Protein CLH-6 C. elegans 58.4 777
NP_610798.1 chloride channel-b D. melanogaster 57.2 779
Other hits (2 of 40) [Show all]SpeciesId(%)Len(aa)
NP_001075680.1 H(+)/Cl(-) exchange transporter 7 O. cuniculus 98.9 804
NP_113756.1 Clcn7 gene product R. norvegicus 98.8 802

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; skin; lymph node; bone marrow; eye; intestine; adipose tissue; thymus; spleen; uterus; lung; kidney; prostate; heart; pancreas; embryonic tissue; mouth; placenta; connective tissue; vascular; thyroid; trachea; blood; mammary gland; mixed; ovary; esophagus; cervix; liver; bladder; bone; stomach; muscle; larynx; lymph; nerve; epididymis; pituitary gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p13
UniSTS entry: Chr 16 RH12098
UniSTS entry: Chr 16 A005U10
UniSTS entry: Chr 16 RH77853
UniSTS entry: Chr 16 RH102989
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AK130196.1 Homo sapiens cDNA FLJ26686 fis, clone MPG06502, highly similar to Chloride channel protein 7 P
AK122944.1 Homo sapiens cDNA FLJ16654 fis, clone TESTI4038284, highly similar to Chloride channel protein 7 P
AF224741.1 Homo sapiens chloride channel protein 7 (CLCN7) mRNA, complete cds P
BC109196.1 Homo sapiens chloride channel 7, mRNA (cDNA clone IMAGE:40005215), partial cds P
BC004946.1 Homo sapiens, clone IMAGE:3615790, mRNA, partial cds PA
BC006158.1 Homo sapiens chloride channel 7, mRNA (cDNA clone IMAGE:3628560), partial cds PA
NM_001287.5 Homo sapiens chloride channel, voltage-sensitive 7 (CLCN7), transcript variant 1, mRNA PA
BC012737.2 Homo sapiens chloride channel 7, mRNA (cDNA clone MGC:15192 IMAGE:4026193), complete cds PA
BC015235.1 Homo sapiens, clone IMAGE:3904225, mRNA A
AK056551.1 Homo sapiens cDNA FLJ31989 fis, clone NT2RP7009012, highly similar to CHLORIDE CHANNEL PROTEIN 7 P
AK292136.1 Homo sapiens cDNA FLJ78478 complete cds P
AK291404.1 Homo sapiens cDNA FLJ78218 complete cds, highly similar to Homo sapiens chloride channel 7, mRNA P
NM_001114331.2 Homo sapiens chloride channel, voltage-sensitive 7 (CLCN7), transcript variant 2, mRNA PA
AK304796.1 Homo sapiens cDNA FLJ58238 complete cds, highly similar to Chloride channel protein 7 P
AK315978.1 Homo sapiens cDNA, FLJ78877 complete cds, highly similar to Chloride channel protein 7 P
Z67743.1 H.sapiens mRNA for CLC-7 chloride channel protein P
U88844.1 Human chloride channel protein (CLCN7) mRNA, partial cds A

EST sequences (10 of 712) [Show all sequences]

AA995140.1 Clone IMAGE:1627007 mixed 3' read A
AI026618.1 Clone IMAGE:1645229 testis 3' read A
AI076529.1 Clone IMAGE:1674868 mixed 3' read A
AI089727.1 Clone IMAGE:1687240 brain 3' read A
CB050248.1 Clone IMAGE:3271585 prostate 3' read A
CB050249.1 Clone IMAGE:3271585 prostate 5' read
CB054516.1 Clone IMAGE:3291459 brain 5' read P
CB054515.1 Clone IMAGE:3291459 brain 3' read A
AI086805.1 Clone IMAGE:1679458 skin 3' read A
BX105890.1 Clone IMAGp998H17139_;_IMAGE:26367 brain A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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