> SEC11 homolog C (S. cerevisiae) (SEC11C)
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UGID:137328     UniGene Hs.45107     Homo sapiens (human)   SEC11C Order cDNA clone, Links
SEC11 homolog C (S. cerevisiae) (SEC11C)

Human protein-coding gene SEC11C. Represented by 270 ESTs from 117 cDNA libraries. Corresponds to reference sequence NM_033280.2. [UniGene 137328 - Hs.45107]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_079744.1 Sec11c gene product M. musculus 100.0 191
XP_003914472.1 PREDICTED: signal peptidase complex catalytic subunit SEC11C isoform 1 P. anubis 100.0 191
NP_150596.1 SEC11C gene product H. sapiens 100.0 191
NP_001003312.1 SEC11C gene product C. lupus familiaris 100.0 191
XP_001489335.2 PREDICTED: signal peptidase complex catalytic subunit SEC11C-like E. caballus 100.0 191
XP_003121761.1 PREDICTED: signal peptidase complex catalytic subunit SEC11C-like S. scrofa 100.0 191
NP_001068643.1 SEC11C gene product B. taurus 100.0 191
XP_002713701.1 PREDICTED: SEC11-like 3-like O. cuniculus 100.0 191
XP_001086489.2 PREDICTED: signal peptidase complex catalytic subunit SEC11C-like isoform 1 M. mulatta 100.0 155
XP_001515047.2 PREDICTED: signal peptidase complex catalytic subunit SEC11C-like, partial O. anatinus 100.0 85
NP_001089755.1 SEC11 homolog C X. laevis 96.6 176
NP_001002521.1 sec11a gene product D. rerio 86.4 176
NP_649676.1 twisted bristles roughened eye D. melanogaster 84.0 174
NP_491092.1 Protein Y54E10BR.5 C. elegans 76.5 178
NP_175669.1 signal peptidase, endoplasmic reticulum-type A. thaliana 68.2 178
XP_001697614.1 signal peptidase, catalytic subunit C. reinhardtii 64.7 197
XP_956930.1 microsomal signal peptidase 18 kDa subunit N. crassa 52.4 165
Other hits (2 of 54) [Show all]SpeciesId(%)Len(aa)
NP_705892.1 Sec11c gene product R. norvegicus 99.5 191
XP_003225993.1 PREDICTED: signal peptidase complex catalytic subunit SEC11C-like A. carolinensis 97.2 176

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; brain; mammary gland; uncharacterized tissue; prostate; mixed; lung; testis; uterus; muscle; liver; pituitary gland; blood; lymph node; bone; spinal cord; thymus; adrenal gland; bladder; connective tissue; skin; eye; intestine; embryonic tissue; placenta; ear; stomach; kidney; ascites; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21.32
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AF212233.1 Homo sapiens microsomal signal peptidase subunit mRNA, complete cds PA
NM_033280.2 Homo sapiens SEC11 homolog C (S. cerevisiae) (SEC11C), mRNA PA
BC009703.1 Homo sapiens SEC11 homolog C (S. cerevisiae), mRNA (cDNA clone MGC:9299 IMAGE:3895819), complete cds PA
AK314107.1 Homo sapiens cDNA, FLJ94795 P
AK307127.1 Homo sapiens cDNA, FLJ97075 P
AK295346.1 Homo sapiens cDNA FLJ57851 complete cds, highly similar to Microsomal signal peptidase 21 kDa subunit (EC 3.4.-.-) P

EST sequences (10 of 270) [Show all sequences]

AA972057.1 Clone IMAGE:1583952 mixed 3' read PA
AA984034.1 Clone IMAGE:1585198 lung 3' read P
AA985561.1 Clone IMAGE:1601202 lung 3' read P
AA989369.1 Clone IMAGE:1607100 mammary gland 3' read PA
AA991962.1 Clone IMAGE:1613513 uncharacterized tissue 3' read PA
AA992003.1 Clone IMAGE:1613609 uncharacterized tissue 3' read PA
AA887219.1 Clone IMAGE:1502028 kidney 3' read PA
AI014584.1 Clone IMAGE:1607614 mammary gland 3' read
AI015791.1 Clone IMAGE:1623372 embryonic tissue 3' read A
AI129251.1 Clone IMAGE:1711886 uterus 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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