> Insulin-like growth factor binding protein 3 (IGFBP3)
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UGID:619193     UniGene Hs.450230     Homo sapiens (human)   IGFBP3 Order cDNA clone, Links
Insulin-like growth factor binding protein 3 (IGFBP3)

Human protein-coding gene IGFBP3. Represented by 2910 ESTs from 342 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 619193 - Hs.450230]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003318467.1 PREDICTED: insulin-like growth factor binding protein 3 isoform 1 P. troglodytes 100.0 296
NP_001013416.1 IGFBP3 gene product H. sapiens 100.0 296
XP_001085359.1 PREDICTED: insulin-like growth factor binding protein 3 M. mulatta 99.7 290
NP_032369.2 Igfbp3 gene product M. musculus 90.1 291
NP_991314.2 igfbp3 gene product D. rerio 63.1 286
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003896057.1 PREDICTED: insulin-like growth factor-binding protein 3 isoform 2 P. anubis 99.3 296
NP_036720.2 insulin-like growth factor-binding protein 3 precursor R. norvegicus 90.1 291

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; placenta; brain; kidney; uncharacterized tissue; intestine; uterus; pancreas; lung; stomach; skin; embryonic tissue; salivary gland; ovary; liver; mixed; eye; heart; testis; mammary gland; spleen; ascites; vascular; prostate; trachea; thymus; mouth; bladder; bone; cervix; larynx; thyroid; muscle; lymph node; pharynx; umbilical cord; esophagus; bone marrow; adipose tissue; ear; adrenal gland; nerve; pituitary gland; blood; amniotic fluid; ganglia; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7p13-p12
UniSTS entry: Chr 7 D7S2379 [Map Viewer]
UniSTS entry: Igfbp3
UniSTS entry: Chr 7 D7S2833
UniSTS entry: Chr 7 D7S2146E
UniSTS entry: Chr 7 IGFBP3-X4.4
UniSTS entry: Chr 7 IGFBP3_1859
UniSTS entry: Chr 7 STS-M35878 [Map Viewer]
UniSTS entry: Chr 7 IGFBP3-X4.5
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (35)

AK130884.1 Homo sapiens cDNA FLJ27374 fis, clone UBA05872 P
AK129951.1 Homo sapiens cDNA FLJ26441 fis, clone KDN02278, highly similar to Homo sapiens insulin-like growth factor binding protein 3 (IGFBP3) P
AK127537.1 Homo sapiens cDNA FLJ45630 fis, clone CHONS2001287, moderately similar to INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 PRECURSOR P
AK125224.1 Homo sapiens cDNA FLJ43234 fis, clone HCHON2002964, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK123735.1 Homo sapiens cDNA FLJ41741 fis, clone HSYRA2003168, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK122873.1 Homo sapiens cDNA FLJ16507 fis, clone HCHON2000364, highly similar to Insulin-like growth factor-binding protein 3 precursor P
NM_000598.4 Homo sapiens insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2, mRNA P
AF370418.1 Homo sapiens PP14214 mRNA, complete cds A
BC064987.1 Homo sapiens insulin-like growth factor binding protein 3, mRNA (cDNA clone MGC:71301 IMAGE:4850456), complete cds PA
M31159.1 Human growth hormone-dependent insulin-like growth factor-binding protein mRNA, complete cds P
NM_001013398.1 Homo sapiens insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1, mRNA P
BC000013.2 Homo sapiens insulin-like growth factor binding protein 3, mRNA (cDNA clone MGC:2305 IMAGE:3506666), complete cds PA
DQ884398.1 Homo sapiens clone BFC06160 insulin-like growth factor binding protein 3 isoform b precursor mRNA, complete cds P
DQ884397.1 Homo sapiens clone BFC06158 insulin-like growth factor binding protein 3 mRNA, complete cds P
DQ884396.1 Homo sapiens clone BFC06155 insulin-like growth factor binding protein 3 isoform b precursor mRNA, complete cds P
AK056274.1 Homo sapiens cDNA FLJ31712 fis, clone NT2RI2006445, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK055632.1 Homo sapiens cDNA FLJ31070 fis, clone HSYRA2001332, highly similar to INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 PRECURSOR P
BC018962.2 Homo sapiens insulin-like growth factor binding protein 3, mRNA (cDNA clone MGC:19695 IMAGE:3506929), complete cds PA
AK315668.1 Homo sapiens cDNA, FLJ96761, highly similar to Homo sapiens insulin-like growth factor binding protein 3 (IGFBP3),mRNA P
AK097201.1 Homo sapiens cDNA FLJ39882 fis, clone SPLEN2016250 P
AK095991.1 Homo sapiens cDNA FLJ38672 fis, clone HSYRA2000371, moderately similar to Insulin-like growth factor-binding protein 3 precursor P
AK095974.1 Homo sapiens cDNA FLJ38655 fis, clone HHDPC2009208, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK095907.1 Homo sapiens cDNA FLJ38588 fis, clone HCHON2009795 P
AK095900.1 Homo sapiens cDNA FLJ38581 fis, clone HCHON2008672, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK095869.1 Homo sapiens cDNA FLJ38550 fis, clone HCHON2002123, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK095864.1 Homo sapiens cDNA FLJ38545 fis, clone HCHON2001604, weakly similar to INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 PRECURSOR P
AK095408.1 Homo sapiens cDNA FLJ38089 fis, clone CTONG2020831 P
AK092447.1 Homo sapiens cDNA FLJ35128 fis, clone PLACE6008768, moderately similar to Insulin-like growth factor-binding protein 3 precursor P
AK091745.1 Homo sapiens cDNA FLJ34426 fis, clone HHDPC2008474, moderately similar to Insulin-like growth factor-binding protein 3 precursor P
AK091706.1 Homo sapiens cDNA FLJ34387 fis, clone HCHON1000191, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK298143.1 Homo sapiens cDNA FLJ53634 complete cds, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK297767.1 Homo sapiens cDNA FLJ52568 complete cds, highly similar to Insulin-like growth factor-binding protein 3 precursor P
AK075483.1 Homo sapiens cDNA PSEC0177 fis, clone OVARC1000287, highly similar to Insulin-like growth factor-binding protein 3 precursor P
S56205.1 insulin-like growth factor binding protein 3 {3' region} [human, tuberous sclerosis cells, mRNA Partial, 704 nt]
X64875.1 H.sapiens mRNA for insulin-like growth factor binding protein-3 P

EST sequences (10 of 2910) [Show all sequences]

AA921724.1 Clone IMAGE:1457204 intestine 3' read A
AA962252.1 Clone IMAGE:1602135 lung 3' read
AA969736.1 Clone IMAGE:1579243 mixed 3' read A
AA996198.1 Clone IMAGE:1604118 lung 3' read
AA904719.1 Clone IMAGE:1504074 mixed 3' read A
AA909646.1 Clone IMAGE:1523484 mixed 3' read A
AI018121.1 Clone IMAGE:1626312 mixed 3' read A
AI028123.1 Clone IMAGE:1646144 parathyroid 3' read A
AI032902.1 Clone IMAGE:1656787 mixed 3' read A
AI050040.1 Clone IMAGE:1700237 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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