Male germ cell-associated kinase (MAK)

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UGID:241162 UniGene Hs.446125 Homo sapiens (human) MAK

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Male germ cell-associated kinase (MAK)

Human protein-coding gene MAK. Represented by 65 ESTs from 39 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 241162 - Hs.446125]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001229886.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MAK gene product	H. sapiens	100.0	647
XP_003950767.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: serine/threonine-protein kinase MAK	P. troglodytes	99.8	647
NP_001139275.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	serine/threonine-protein kinase MAK isoform 1	M. musculus	91.2	645
NP_001087126.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	male germ cell-associated kinase	X. laevis	78.5	647
NP_956240.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	mak gene product	D. rerio	73.8	632
XP_001697865.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	mitogen-activated protein kinase 7	C. reinhardtii	73.2	287
NP_723501.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CG42366, isoform A	D. melanogaster	72.8	294
NP_492493.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein DYF-5, isoform a	C. elegans	71.1	367
NP_567574.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	putative serine/threonine protein kinase	A. thaliana	62.6	321
XP_956947.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein NCU01498	N. crassa	49.3	144
Other hits (2 of 56) [Show all]		Species	Id(%)	Len(aa)
XP_003897097.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: serine/threonine-protein kinase MAK isoform 2	P. anubis	99.2	647
XP_001088297.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: serine/threonine-protein kinase MAK-like isoform 2	M. mulatta	99.2	622

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	eye; testis; uncharacterized tissue; mixed; intestine; esophagus; brain; lung; kidney; larynx; blood; lymph node; muscle

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	6
Map position:	6p24
UniSTS entry:	Chr 6	RH98702
UniSTS entry:	Chr 1	D11S2560
UniSTS entry:	Chr 6	RH94354

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_005906.4	Homo sapiens male germ cell-associated kinase (MAK), transcript variant 1, mRNA	P
AK314408.1	Homo sapiens cDNA, FLJ95188	P
AK310329.1	Homo sapiens cDNA, FLJ17371	P
AK097831.1	Homo sapiens cDNA FLJ40512 fis, clone TESTI2046439, highly similar to Serine/threonine-protein kinase MAK (EC 2.7.11.22)	P
BC033002.1	Homo sapiens cDNA clone IMAGE:4828626, containing frame-shift errors	PA
AF505623.1	Homo sapiens male germ cell-associated kinase (MAK) mRNA, complete cds	P
AB593146.1	Homo sapiens MAK mRNA for serine/threonine-protein kinase MAK, complete cds, clone: HP09007-RBdS070K07	P
NM_001242385.1	Homo sapiens male germ cell-associated kinase (MAK), transcript variant 2, mRNA	P
JN135248.1	Homo sapiens male germ cell-associated kinase retina-specific isoform (MAK) mRNA, partial cds
NM_001242957.1	Homo sapiens male germ cell-associated kinase (MAK), transcript variant 3, mRNA	P
JN226411.1	Homo sapiens male germ cell-associated kinase retinal-enriched isoform (MAK) mRNA, complete cds, alternatively spliced	P
BC039825.1	Homo sapiens male germ cell-associated kinase, mRNA (cDNA clone MGC:48725 IMAGE:5167621), complete cds	PA

EST sequences (10 of 65) [Show all sequences]

AI015438.1	Clone IMAGE:1641110	testis	3' read
AI138938.1	Clone IMAGE:1735656	testis	3' read	PA
BX105286.1	Clone IMAGp998I19884_;_IMAGE:381786	eye		P
AI221451.1	Clone IMAGE:1841007	mixed	3' read	A
AI630776.1	Clone IMAGE:2273263	lung	3' read
AI444804.1	Clone RET1F12	eye
AF112226.1	Clone YTLEST15	larynx
CD104558.1	Clone IMAGE:30371041	mixed	5' read	P
AI868638.1	Clone IMAGE:2068181	mixed	3' read
CB854592.1	Clone UI-CF-DU1-abf-m-22-0-UI	lung	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria