> Cyclin-dependent kinase 18 (CDK18)
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UGID:240439     UniGene Hs.445402     Homo sapiens (human)   CDK18 Order cDNA clone, Links
Cyclin-dependent kinase 18 (CDK18)

Human protein-coding gene CDK18. Represented by 401 ESTs from 164 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 240439 - Hs.445402]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_997668.1 CDK18 gene product H. sapiens 100.0 503
XP_003308726.1 PREDICTED: LOW QUALITY PROTEIN: cyclin-dependent kinase 18 P. troglodytes 99.8 483
NP_032821.1 Cdk18 gene product M. musculus 95.6 450
XP_001919335.2 PREDICTED: cyclin-dependent kinase 18-like D. rerio 90.8 464
NP_001080154.1 cyclin-dependent kinase 17 X. laevis 82.6 499
NP_501372.1 Protein PCT-1, isoform a C. elegans 75.9 407
NP_001036581.1 Ecdysone-induced protein 63E, isoform F D. melanogaster 67.2 421
NP_015294.1 Pho85p S. cerevisiae 63.6 294
XP_958274.1 negative regulator of the PHO system N. crassa 62.7 322
NP_566911.1 cyclin-dependent kinase A-1 A. thaliana 59.1 291
XP_001698637.1 cyclin dependent protein kinase C. reinhardtii 59.0 290
Other hits (2 of 67) [Show all]SpeciesId(%)Len(aa)
XP_003893272.1 PREDICTED: cyclin-dependent kinase 18 P. anubis 99.4 473
XP_848622.2 PREDICTED: LOW QUALITY PROTEIN: cyclin-dependent kinase 18 isoform 1 C. lupus familiaris 96.3 461

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; mixed; intestine; spinal cord; uncharacterized tissue; nerve; placenta; lung; testis; pancreas; embryonic tissue; kidney; uterus; prostate; heart; ovary; bladder; thymus; esophagus; mouth; skin; thyroid; adrenal gland; liver; larynx; trachea; lymph; ascites; lymph node; connective tissue; spleen; mammary gland; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q31-q32
UniSTS entry: Chr 1 RH80187
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (21)

BT007299.1 Homo sapiens PCTAIRE-motif protein kinase 3 mRNA, complete cds P
AK126879.1 Homo sapiens cDNA FLJ44931 fis, clone BRAMY3015799, highly similar to Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) P
NM_002596.3 Homo sapiens cyclin-dependent kinase 18 (CDK18), transcript variant 3, mRNA PA
AY353239.1 Homo sapiens PCTAIRE protein kinase 3-like protein (PCTK3) mRNA, partial sequence, alternatively spliced P
AY353240.1 Homo sapiens PCTAIRE protein kinase 3 (PCTK3) mRNA, 5' UTR, alternatively spliced
AY353238.1 Homo sapiens PCTAIRE protein kinase 3 isoform b (PCTK3) mRNA, complete cds, alternatively spliced P
AY353237.1 Homo sapiens PCTAIRE protein kinase 3 isoform a (PCTK3) mRNA, complete cds, alternatively spliced P
AL161977.1 Homo sapiens mRNA; cDNA DKFZp761L1515 (from clone DKFZp761L1515) PA
NM_212503.2 Homo sapiens cyclin-dependent kinase 18 (CDK18), transcript variant 1, mRNA PA
NM_212502.2 Homo sapiens cyclin-dependent kinase 18 (CDK18), transcript variant 2, mRNA PA
AB209307.1 Homo sapiens mRNA for PCTAIRE protein kinase 3 isoform b variant protein P
BC000281.2 Homo sapiens PCTAIRE protein kinase 3, mRNA (cDNA clone IMAGE:3357514), partial cds PA
BC009223.2 Homo sapiens PCTAIRE protein kinase 3, mRNA (cDNA clone IMAGE:3928693), partial cds A
BC011526.1 Homo sapiens PCTAIRE protein kinase 3, mRNA (cDNA clone MGC:9361 IMAGE:3855304), complete cds PA
AK308913.1 Homo sapiens cDNA, FLJ98954 P
AK293756.1 Homo sapiens cDNA FLJ56472 complete cds, highly similar to Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) P
AK296320.1 Homo sapiens cDNA FLJ53597 complete cds, highly similar to Homo sapiens PCTAIRE protein kinase 3 (PCTK3), transcript variant 1, mRNA P
AK295654.1 Homo sapiens cDNA FLJ55877 complete cds P
AK295272.1 Homo sapiens cDNA FLJ55785 complete cds, highly similar to Serine/threonine-protein kinase PCTAIRE-3 (EC 2.7.11.22) P
X66362.1 H.sapiens mRNA PCTAIRE-3 for serine/threonine protein kinase P
BC040529.1 Homo sapiens PCTAIRE protein kinase 3, mRNA (cDNA clone IMAGE:5259725), complete cds PA

EST sequences (10 of 401) [Show all sequences]

AA975866.1 Clone IMAGE:1555639 kidney 3' read
AI089808.1 Clone IMAGE:1686425 brain 3' read A
AI143268.1 Clone IMAGE:1708636 heart 3' read
CB045518.1 Clone IMAGE:3218531 intestine 3' read A
CB045519.1 Clone IMAGE:3218531 intestine 5' read
CB145167.1 Clone L11SNU354s1-10-C07 liver 5' read P
AI248743.1 Clone IMAGE:1850715 mixed 3' read
AI290797.1 Clone IMAGE:1881687 lung 3' read
AI346319.1 Clone IMAGE:1925913 intestine 3' read
T07927.1 Clone HHCF34 brain P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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