> Transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) (TLE4)
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UGID:239250     UniGene Hs.444213     Homo sapiens (human)   TLE4 Order cDNA clone, Links
Transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) (TLE4)

Human protein-coding gene TLE4. Represented by 415 ESTs from 142 cDNA libraries. Corresponds to reference sequence NM_007005.3. [UniGene 239250 - Hs.444213]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001151507.1 PREDICTED: transducin-like enhancer protein 4 isoform 13 P. troglodytes 100.0 804
NP_035730.2 Tle4 gene product M. musculus 100.0 772
NP_008936.2 TLE4 gene product H. sapiens 100.0 772
XP_003213615.1 PREDICTED: transducin-like enhancer protein 4-like, partial M. gallopavo 100.0 299
XP_001103029.1 PREDICTED: transducin-like enhancer protein 4 isoform 10 M. mulatta 99.9 804
NP_001075052.1 TLE4 gene product B. taurus 99.9 773
NP_062014.2 transducin-like enhancer protein 4 R. norvegicus 99.9 748
XP_001494219.3 PREDICTED: transducin-like enhancer protein 4-like E. caballus 99.9 726
XP_003341708.1 PREDICTED: LOW QUALITY PROTEIN: transducin-like enhancer protein 4-like M. domestica 99.7 772
NP_989568.1 TLE4 gene product G. gallus 99.7 772
XP_001924230.3 PREDICTED: transducin-like enhancer protein 4 isoform 1 S. scrofa 99.7 772
XP_533519.3 PREDICTED: transducin-like enhancer protein 4 C. lupus familiaris 99.7 762
XP_004005338.1 PREDICTED: transducin-like enhancer protein 4 O. aries 99.6 770
NP_001084260.1 transducin-like enhancer of split 4 X. laevis 98.8 771
NP_571855.1 gro1 gene product D. rerio 88.7 770
NP_733133.1 groucho, isoform A D. melanogaster 79.3 718
NP_491932.1 Protein UNC-37 C. elegans 67.6 348
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_003216520.1 PREDICTED: transducin-like enhancer protein 4-like A. carolinensis 99.5 772
XP_003911893.1 PREDICTED: transducin-like enhancer protein 4 isoform 4 P. anubis 99.5 772

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; lymph node; uncharacterized tissue; mixed; embryonic tissue; eye; lung; placenta; intestine; stomach; skin; pineal gland; bone marrow; blood; connective tissue; muscle; kidney; pituitary gland; adrenal gland; ovary; trachea; uterus; thymus; liver; vascular; parathyroid; heart; bone; mammary gland; nerve; pancreas; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q21.31
UniSTS entry: Chr 9 RH44484
UniSTS entry: Chr 9 RH78181 [Map Viewer]
UniSTS entry: TLE4
UniSTS entry: Chr 9 STS-AA035418 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

AF068197.1 Homo sapiens BCE-1 mRNA, complete cds
BC045650.1 Homo sapiens transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila), mRNA (cDNA clone MGC:43541 IMAGE:5268902), complete cds PA
BC059405.1 Homo sapiens transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila), mRNA (cDNA clone MGC:71782 IMAGE:5296117), complete cds PA
NM_007005.3 Homo sapiens transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) (TLE4), mRNA P
BC060038.1 Homo sapiens transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila), mRNA (cDNA clone IMAGE:4104322) A
BC063695.1 Homo sapiens cDNA clone IMAGE:4748672, partial cds A
AB033087.1 Homo sapiens mRNA for KIAA1261 protein, partial cds P
AL162059.1 Homo sapiens mRNA; cDNA DKFZp547P103 (from clone DKFZp547P103) PA
CR749553.1 Homo sapiens mRNA; cDNA DKFZp686N15112 (from clone DKFZp686N15112) A
M99439.1 Human transducin-like enhancer protein (TLE4) mRNA, 3' end P
AK057236.1 Homo sapiens cDNA FLJ32674 fis, clone TESTI1000142, highly similar to TRANSDUCIN-LIKE ENHANCER PROTEIN 4 P
AK296342.1 Homo sapiens cDNA FLJ58005 complete cds, highly similar to Transducin-like enhancer protein 4 P
AK302709.1 Homo sapiens cDNA FLJ61488 complete cds, highly similar to Transducin-like enhancer protein 4 P
BC036369.1 Homo sapiens transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila), mRNA (cDNA clone IMAGE:4824600) PA
HQ234317.1 Homo sapiens clone TLE4_E8_E6 TLE4 mRNA, partial sequence P
HQ283388.1 Homo sapiens clone TLE4_E8_E5 TLE4 mRNA, partial sequence P

EST sequences (10 of 415) [Show all sequences]

AA961475.1 Clone IMAGE:1579679 mixed 3' read A
AA984747.1 Clone IMAGE:1630406 brain 3' read P
AI018740.1 Clone IMAGE:1638663 testis 3' read P
AI031782.1 Clone IMAGE:1649958 parathyroid 3' read P
AI130717.1 Clone IMAGE:1709798 heart 3' read A
AI131010.1 Clone IMAGE:1709727 heart 3' read A
AI140694.1 Clone IMAGE:1738186 testis 3' read A
AI149329.1 Clone IMAGE:1715576 placenta 3' read
AI149351.1 Clone IMAGE:1716090 placenta 3' read
BX099555.1 Clone IMAGp998E211118_;_IMAGE:471548 uterus P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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