> Minichromosome maintenance complex component 6 (MCM6)
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UGID:239155     UniGene Hs.444118     Homo sapiens (human)   MCM6 Order cDNA clone, Links
Minichromosome maintenance complex component 6 (MCM6)

Human protein-coding gene MCM6. Represented by 737 ESTs from 264 cDNA libraries. Corresponds to reference sequence NM_005915.5. [UniGene 239155 - Hs.444118]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001096068.1 PREDICTED: DNA replication licensing factor MCM6 isoform 1 M. mulatta 100.0 820
XP_001154732.1 PREDICTED: DNA replication licensing factor MCM6 isoform 2 P. troglodytes 100.0 820
NP_005906.2 MCM6 gene product H. sapiens 100.0 820
XP_003909220.1 PREDICTED: DNA replication licensing factor MCM6-like P. anubis 100.0 685
XP_001489748.2 PREDICTED: DNA replication licensing factor MCM6-like E. caballus 99.6 820
XP_533338.3 PREDICTED: DNA replication licensing factor MCM6 C. lupus familiaris 99.5 820
NP_032593.1 Mcm6 gene product M. musculus 97.9 820
NP_001080590.1 zygotic DNA replication licensing factor mcm6-B X. laevis 90.2 824
NP_001076318.1 mcm6 gene product D. rerio 89.7 816
NP_511065.1 minichromosome maintenance 6 D. melanogaster 76.1 806
NP_001023011.1 Protein MCM-6, isoform a C. elegans 71.4 804
XP_962193.2 DNA replication licensing factor mcm6 N. crassa 64.1 750
NP_011314.2 Mcm6p S. cerevisiae 62.4 742
XP_001703255.1 minichromosome maintenance protein 6 C. reinhardtii 61.5 683
NP_680393.1 minichromosome maintenance protein 6 A. thaliana 60.6 823
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_004004776.1 PREDICTED: DNA replication licensing factor MCM6 O. aries 99.4 820
NP_001039699.1 MCM6 gene product B. taurus 99.2 820

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; thymus; embryonic tissue; kidney; mammary gland; muscle; intestine; connective tissue; bone marrow; eye; mouth; mixed; heart; placenta; prostate; liver; spleen; blood; skin; lung; pharynx; trachea; ear; pancreas; uterus; cervix; vascular; ascites; bone; esophagus; lymph node; ovary; lymph; stomach; salivary gland; larynx; tonsil; bladder; pituitary gland; nerve; ganglia; adipose tissue; thyroid; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q21
UniSTS entry: Chr 2 RH93355
UniSTS entry: Chr 2 G29257
UniSTS entry: Chr 2 RH67906
UniSTS entry: Chr 2 RH77976
UniSTS entry: Chr 2 RH46031 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_005915.5 Homo sapiens minichromosome maintenance complex component 6 (MCM6), mRNA PA
U46838.1 Human p105MCM mRNA, complete cds PA
AK312575.1 Homo sapiens cDNA, FLJ92950, Homo sapiens MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) (MCM6), mRNA P
BC032374.1 Homo sapiens minichromosome maintenance complex component 6, mRNA (cDNA clone MGC:40308 IMAGE:5122786), complete cds PA
AK299236.1 Homo sapiens cDNA FLJ51591 partial cds, highly similar to DNA replication licensing factor MCM6 P
AK303455.1 Homo sapiens cDNA FLJ51590 complete cds, moderately similar to DNA replication licensing factor MCM6 P
BC020268.1 Homo sapiens minichromosome maintenance complex component 6, mRNA (cDNA clone IMAGE:5094951) PA
BC008774.1 Homo sapiens MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae), mRNA (cDNA clone IMAGE:3140421), with apparent retained intron PA
D84557.1 Homo sapiens mRNA for HsMcm6, complete cds P

EST sequences (10 of 737) [Show all sequences]

AA976533.1 Clone IMAGE:1587847 uncharacterized tissue 3' read A
AA993000.1 Clone IMAGE:1622715 embryonic tissue 3' read A
BX118733.1 Clone IMAGp998J1881_;_IMAGE:109169 mixed P
AI183516.1 Clone IMAGE:1734650 testis 3' read A
AI190414.1 Clone IMAGE:1732819 heart 3' read A
AI215422.1 Clone IMAGE:1844337 mixed 3' read A
CB111680.1 Clone L5HLK1-3-E01 liver 5' read P
CB124587.1 Clone L5HLK1s1-8-C10 liver 5' read P
CB126777.1 Clone L5HLK1s1-25-G05 liver 5' read P
CB126015.1 Clone C1SNU17-15-G07 cervix 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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