> DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11)
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UGID:238997     UniGene Hs.443960     Homo sapiens (human)   DDX11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11)

Human protein-coding gene DDX11. Represented by 223 ESTs from 122 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 238997 - Hs.443960]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_689651.1 DDX11 gene product H. sapiens 100.0 969
NP_001159771.1 ribosomal protein L17 X. laevis 93.0 86
NP_001003919.1 Ddx11 gene product M. musculus 83.1 878
NP_001007320.1 ddx11 gene product D. rerio 65.9 877
XP_001700860.1 hypothetical protein CHLREDRAFT_113235 C. reinhardtii 50.9 272
NP_569898.1 CG11403 D. melanogaster 50.5 295
NP_178107.1 chromosome transmission fidelity protein 1 A. thaliana 47.0 198
Other hits (2 of 44) [Show all]SpeciesId(%)Len(aa)
XP_003313865.1 PREDICTED: probable ATP-dependent RNA helicase DDX11 isoform 1 P. troglodytes 99.2 905
XP_001114510.2 PREDICTED: putative ATP-dependent RNA helicase DDX11-like protein-like isoform 4 M. mulatta 98.1 909

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; brain; lung; uterus; embryonic tissue; intestine; liver; eye; muscle; vascular; mixed; placenta; thymus; lymph node; stomach; blood; skin; trachea; kidney; ovary; mammary gland; pharynx; testis; cervix; spleen; ascites; lymph; pancreas; prostate; bone; epididymis; connective tissue; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p11
UniSTS entry: Chr 12 RH65252
UniSTS entry: Chr 12 RH80562
UniSTS entry: Chr 12 ECD03348
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

BC050069.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae), mRNA (cDNA clone MGC:50970 IMAGE:5271949), complete cds PA
BC050522.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae), mRNA (cDNA clone MGC:57502 IMAGE:6471750), complete cds PA
NM_004399.2 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11), transcript variant 2, mRNA PA
BC111733.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae), mRNA (cDNA clone MGC:133249 IMAGE:40035545), complete cds P
DQ786287.1 Homo sapiens clone HLS_IMAGE_470930 mRNA sequence A
NM_030653.3 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11), transcript variant 1, mRNA PA
NM_152438.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11), transcript variant 3, mRNA PA
BC011264.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae), mRNA (cDNA clone IMAGE:3451006), containing frame-shift errors PA
BC148224.1 Homo sapiens cDNA clone IMAGE:40035543, containing frame-shift errors P
AK297607.1 Homo sapiens cDNA FLJ60129 complete cds, highly similar to Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) P
AK303139.1 Homo sapiens cDNA FLJ56669 complete cds, highly similar to Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) P
U33833.1 Human CHL1-related helicase (CHLR1) mRNA, complete cds P
X99583.1 H.sapiens mRNA for CHL1 protein PA
BC001591.2 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae), mRNA (cDNA clone IMAGE:2987815), containing frame-shift errors PA
BC012834.2 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae), mRNA (cDNA clone IMAGE:3536680) PA
U75967.1 Human CHL1 potential helicase (CHLR1), complete cds PA
U75968.1 Human clone C3 CHL1 protein (CHLR1) mRNA, alternatively spliced, complete cds PA
U75969.1 Human clone C9 CHL1 protein (CHLR1) mRNA, alternatively spliced, partial cds PA
NM_001257145.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11), transcript variant 5, mRNA PA
NM_001257144.1 Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (DDX11), transcript variant 4, mRNA PA

EST sequences (10 of 223) [Show all sequences]

AA973745.1 Clone IMAGE:1586035 uncharacterized tissue 3' read A
AI138714.1 Clone IMAGE:1710451 uterus 3' read A
AI174253.1 Clone IMAGE:1684381 brain 3' read
AI270182.1 Clone IMAGE:1962720 intestine 3' read A
AI342087.1 Clone IMAGE:1946164 uncharacterized tissue 3' read A
AI569555.1 Clone IMAGE:2180379 uterus 3' read A
AI632422.1 Clone IMAGE:2182039 uterus 3' read A
AI671376.1 Clone IMAGE:2316605 kidney 3' read A
AL047846.1 Clone DKFZp586J1622 uterus P
BX280645.1 Clone IMAGp998K1813317_;_IMAGE:6056201 skin


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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