> Superoxide dismutase 1, soluble (SOD1)
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UGID:238951     UniGene Hs.443914     Homo sapiens (human)   SOD1 Order cDNA clone, Links
Superoxide dismutase 1, soluble (SOD1)

Human protein-coding gene SOD1. Represented by 1497 ESTs from 430 cDNA libraries. Corresponds to reference sequence NM_000454.4. [UniGene 238951 - Hs.443914]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001009025.1 SOD1 gene product P. troglodytes 100.0 153
NP_000445.1 SOD1 gene product H. sapiens 100.0 153
NP_035564.1 Sod1 gene product M. musculus 89.0 153
NP_571369.1 sod1 gene product D. rerio 74.7 153
NP_001080933.1 superoxide dismutase [Cu-Zn] B X. laevis 72.8 150
NP_476735.1 superoxide dismutase, isoform A D. melanogaster 64.7 152
XP_964291.2 superoxide dismutase N. crassa 62.1 152
NP_012638.1 Sod1p S. cerevisiae 61.4 152
NP_001021957.1 Protein SOD-1, isoform b C. elegans 61.3 155
NP_197311.1 copper/zinc superoxide dismutase 3 A. thaliana 60.1 162
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
NP_001027976.1 SOD1 gene product M. mulatta 92.9 153
XP_003895592.1 PREDICTED: superoxide dismutase [Cu-Zn] P. anubis 92.9 153

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; lung; mixed; eye; liver; skin; testis; uterus; placenta; prostate; intestine; uncharacterized tissue; stomach; pituitary gland; ear; pharynx; spleen; ascites; bone marrow; heart; connective tissue; ovary; kidney; bone; mammary gland; blood; embryonic tissue; vascular; lymph node; muscle; adrenal gland; thymus; mouth; lymph; cervix; salivary gland; parathyroid; thyroid; trachea; umbilical cord; esophagus; spinal cord; tonsil; bladder; adipose tissue; ganglia; nerve; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.11
UniSTS entry: Chr 8 MARC_26673-26674:1036188363:1
UniSTS entry: Sod1
UniSTS entry: Chr 21 G20764
UniSTS entry: Chr 21 SHGC-87564 [Map Viewer]
UniSTS entry: Chr 21 G34694
UniSTS entry: Chr 21 GDB:185171
UniSTS entry: Chr 21 GDB:374780
UniSTS entry: A006F27
UniSTS entry: Chr 21 PMC122237P1
UniSTS entry: Chr 21 SOD1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BT006676.1 Homo sapiens superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) mRNA, complete cds P
NM_000454.4 Homo sapiens superoxide dismutase 1, soluble (SOD1), mRNA PA
AY450286.1 Homo sapiens superoxide dismutase (SOD) mRNA, complete cds P
CR450355.1 Homo sapiens full open reading frame cDNA clone RZPDo834A053D for gene SOD1, superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); complete cds; without stopcodon P
CR541742.1 Homo sapiens full open reading frame cDNA clone RZPDo834E0529D for gene SOD1, superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); complete cds, incl. stopcodon P
BC001034.1 Homo sapiens superoxide dismutase 1, soluble, mRNA (cDNA clone MGC:2325 IMAGE:3140145), complete cds PA
EF151142.1 Homo sapiens superoxide dismutase 1 (SOD1) mRNA, complete cds P
EF143990.1 Homo sapiens superoxide dismutase 1 (SOD1) mRNA, partial cds
AY049787.1 Homo sapiens soluble superoxide dismutase 1 (SOD1) gene, complete cds P
AK312116.1 Homo sapiens cDNA, FLJ92398, Homo sapiens superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1), mRNA P
X02317.1 Human mRNA for Cu/Zn superoxide dismutase (SOD) P

EST sequences (10 of 1497) [Show all sequences]

AA961435.1 Clone IMAGE:1599566 uncharacterized tissue 3' read P
AA961798.1 Clone IMAGE:1598407 uncharacterized tissue 3' read
AA994301.1 Clone IMAGE:1631239 mammary gland 3' read P
AA908860.1 Clone IMAGE:1522713 lung 3' read PA
AI023156.1 Clone IMAGE:1651753 skin 3' read A
AI023204.1 Clone IMAGE:1643415 testis 3' read P
AI027606.1 Clone IMAGE:1645436 testis 3' read P
AI027925.1 Clone IMAGE:1645493 testis 3' read P
AI031921.1 Clone IMAGE:1650004 parathyroid 3' read PA
AI034017.1 Clone IMAGE:1646703 parathyroid 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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