> Sterol regulatory element binding transcription factor 2 (SREBF2)
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UGID:238295     UniGene Hs.443258     Homo sapiens (human)   SREBF2 Order cDNA clone, Links
Sterol regulatory element binding transcription factor 2 (SREBF2)

Human protein-coding gene SREBF2. Represented by 878 ESTs from 276 cDNA libraries. Corresponds to reference sequence NM_004599.2. [UniGene 238295 - Hs.443258]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004590.2 SREBF2 gene product H. sapiens 100.0 1140
XP_003317335.1 PREDICTED: LOW QUALITY PROTEIN: sterol regulatory element-binding protein 2 P. troglodytes 99.8 1209
NP_150087.1 Srebf2 gene product M. musculus 95.9 1129
NP_001085554.2 sterol regulatory element-binding protein 2 X. laevis 77.7 1094
NP_001082935.1 srebf2 gene product D. rerio 58.5 1092
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_003905671.1 PREDICTED: sterol regulatory element-binding protein 2 P. anubis 99.4 1117
XP_001101257.2 PREDICTED: sterol regulatory element-binding protein 2-like M. mulatta 99.2 1089

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; uncharacterized tissue; pharynx; embryonic tissue; intestine; lymph node; eye; pancreas; placenta; mixed; lung; lymph; prostate; umbilical cord; blood; heart; kidney; uterus; ovary; testis; bone marrow; liver; connective tissue; thyroid; bone; larynx; spleen; adrenal gland; amniotic fluid; tonsil; muscle; ascites; mammary gland; cervix; stomach; adipose tissue; thymus; mouth; salivary gland; nerve; esophagus; ganglia; parathyroid; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q13
UniSTS entry: Chr 22 SHGC-30242 [Map Viewer]
UniSTS entry: Chr 22 SHGC-12896
UniSTS entry: Chr 22 WI-20973 [Map Viewer]
UniSTS entry: Chr 22 SHGC-12896
UniSTS entry: Chr 22 GDB:592857
UniSTS entry: Chr 22 RH80373
UniSTS entry: Chr 1 D8S2278
UniSTS entry: RH99122
UniSTS entry: Chr 22 WI-12706 [Map Viewer]
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BC051385.1 Homo sapiens sterol regulatory element binding transcription factor 2, mRNA (cDNA clone MGC:54238 IMAGE:5497929), complete cds PA
BC051799.1 Homo sapiens sterol regulatory element binding transcription factor 2, mRNA (cDNA clone IMAGE:5498684), partial cds PA
BC056158.1 Homo sapiens sterol regulatory element binding transcription factor 2, mRNA (cDNA clone MGC:65097 IMAGE:6169568), complete cds PA
AK129736.1 Homo sapiens cDNA FLJ26225 fis, clone ADG08705
NM_004599.2 Homo sapiens sterol regulatory element binding transcription factor 2 (SREBF2), mRNA PA
U02031.1 Human sterol regulatory element binding protein-2 mRNA, complete cds P
CT841522.1 Homo sapiens SREBF2 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.SREBF2.V2) P
AL834221.1 Homo sapiens mRNA; cDNA DKFZp434N1610 (from clone DKFZp434N1610) PA
AK299914.1 Homo sapiens cDNA FLJ61379 complete cds, highly similar to Sterol regulatory element-binding protein 2 P

EST sequences (10 of 878) [Show all sequences]

AA988326.1 Clone IMAGE:1607047 mammary gland 3' read A
AI017428.1 Clone IMAGE:1635685 kidney 3' read A
AI052082.1 Clone IMAGE:1652648 mixed 3' read A
AI074214.1 Clone IMAGE:1681977 skin 3' read A
R21492.1 Clone IMAGE:31274 brain 5' read
AI127961.1 Clone IMAGE:1711353 uterus 3' read A
AI128994.1 Clone IMAGE:1663227 skin 3' read A
AI140334.1 Clone IMAGE:1693194 heart 3' read A
AI144239.1 Clone IMAGE:1706869 heart 3' read A
CB050466.1 Clone IMAGE:3272204 prostate 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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