> Tumor protein p53 binding protein 1 (TP53BP1)
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UGID:236005     UniGene Hs.440968     Homo sapiens (human)   TP53BP1 Order cDNA clone, Links
Tumor protein p53 binding protein 1 (TP53BP1)

Human protein-coding gene TP53BP1. Represented by 389 ESTs from 194 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 236005 - Hs.440968]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001135452.1 TP53BP1 gene product H. sapiens 100.0 1976
XP_523062.3 PREDICTED: tumor suppressor p53-binding protein 1 isoform 5 P. troglodytes 99.7 1976
NP_038763.3 Trp53bp1 gene product M. musculus 89.2 1968
NP_001082071.1 tumor protein p53 binding protein 1 X. laevis 62.8 1236
NP_001073639.1 zgc:158452 gene product D. rerio 61.0 493
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_001107285.2 PREDICTED: tumor suppressor p53-binding protein 1-like isoform 4 M. mulatta 98.9 1976
NP_001162434.1 tumor suppressor p53-binding protein 1 P. anubis 98.8 1971

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mammary gland; skin; embryonic tissue; uterus; esophagus; testis; thyroid; lung; prostate; uncharacterized tissue; mixed; spinal cord; ovary; intestine; placenta; eye; kidney; cervix; tonsil; mouth; spleen; thymus; trachea; liver; heart; larynx; muscle; lymph node; ascites; connective tissue; pancreas; blood; parathyroid; bone marrow; bladder; adipose tissue; pineal gland; bone; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q15-q21
UniSTS entry: Chr 15 RH68009 [Map Viewer]
UniSTS entry: Chr 15 RH44505
UniSTS entry: Chr 15 RH15708
UniSTS entry: Chr 15 REN36874
UniSTS entry: Chr 15 REN36876
UniSTS entry: Chr 15 REN36872
UniSTS entry: Chr 15 REN36875
UniSTS entry: Chr 15 REN36873
UniSTS entry: Chr 15 REN36839
UniSTS entry: Chr 15 REN36818
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AF078776.1 Homo sapiens p53 tumor suppressor-binding protein 1 mRNA, complete cds P
BX537418.1 Homo sapiens mRNA; cDNA DKFZp686B146 (from clone DKFZp686B146); complete cds PA
AK123418.1 Homo sapiens cDNA FLJ41424 fis, clone BRHIP2003748, highly similar to Tumor suppressor p53-binding protein 1 P
NM_005657.2 Homo sapiens tumor protein p53 binding protein 1 (TP53BP1), transcript variant 3, mRNA PA
BC063119.1 Homo sapiens tumor protein p53 binding protein, 1, mRNA (cDNA clone IMAGE:6453406), with apparent retained intron PA
AB210025.1 Homo sapiens mRNA for TP53BP1 variant protein, partial cds, clone: ha04849 P
DQ102772.1 Homo sapiens tumor suppressor p53-binding protein 1 (TP53BP1) mRNA, partial cds, alternatively spliced
BC112161.1 Homo sapiens tumor protein p53 binding protein 1, mRNA (cDNA clone MGC:138366 IMAGE:8327629), complete cds P
AK292915.1 Homo sapiens cDNA FLJ78617 partial cds P
AK307405.1 Homo sapiens cDNA, FLJ97353 P
BC017846.1 Homo sapiens cDNA clone IMAGE:4273542, partial cds A
NM_001141980.1 Homo sapiens tumor protein p53 binding protein 1 (TP53BP1), transcript variant 1, mRNA PA
NM_001141979.1 Homo sapiens tumor protein p53 binding protein 1 (TP53BP1), transcript variant 2, mRNA PA
AK295764.1 Homo sapiens cDNA FLJ56510 complete cds, highly similar to Tumor suppressor p53-binding protein 1 P
U09477.1 Human clone 53BP1 p53-binding protein mRNA, partial cds P

EST sequences (10 of 389) [Show all sequences]

AA908289.1 Clone IMAGE:1441674 mammary gland 3' read PA
AA927382.1 Clone IMAGE:1542238 mixed 3' read PA
AI024078.1 Clone IMAGE:1642884 testis 3' read PA
AI039069.1 Clone IMAGE:1657859 embryonic tissue 3' read A
AI041506.1 Clone IMAGE:1648853 parathyroid 3' read PA
AI123806.1 Clone IMAGE:1651292 mixed 3' read PA
AI215950.1 Clone IMAGE:1840389 testis 3' read A
AI250764.1 Clone IMAGE:1858568 mixed 3' read P
CB119575.1 Clone L8SCK0-27-G07 liver 5' read P
R32690.1 Clone IMAGE:133603 placenta 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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