> Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4)
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UGID:234567     UniGene Hs.439530     Homo sapiens (human)   DYRK4
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4)

Human protein-coding gene DYRK4. Represented by 192 ESTs from 108 cDNA libraries. Corresponds to reference sequence NM_003845.1. [UniGene 234567 - Hs.439530]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003836.1 DYRK4 gene product H. sapiens 100.0 519
NP_997093.2 Dyrk4 gene product M. musculus 86.2 631
XP_693389.3 PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 4 D. rerio 70.8 571
NP_523564.1 smell impaired 35A, isoform A D. melanogaster 65.7 484
XP_001695011.1 dual-specificity tyrosine regulated protein kinase 1 C. reinhardtii 65.3 356
NP_001040950.1 Protein MBK-2, isoform d C. elegans 61.8 398
NP_001088793.1 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 X. laevis 61.0 415
XP_960871.1 hypothetical protein NCU06638 N. crassa 58.6 445
NP_001031970.1 YAK1-like protein 1 A. thaliana 52.8 250
NP_012394.1 Yak1p S. cerevisiae 48.3 230
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
XP_522326.3 PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 4 isoform 4 P. troglodytes 99.1 545
XP_003905875.1 PREDICTED: LOW QUALITY PROTEIN: dual specificity tyrosine-phosphorylation-regulated kinase 4 P. anubis 97.0 634

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; uncharacterized tissue; lung; mixed; kidney; uterus; eye; lymph node; pancreas; ovary; ear; cervix; trachea; tonsil; connective tissue; mouth; placenta; intestine; embryonic tissue; heart; mammary gland; skin; blood; larynx; stomach; thyroid; ascites; bone; umbilical cord; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p13.32
UniSTS entry: Chr 12 RH15741
UniSTS entry: Chr 12 A007I33 [Map Viewer]
UniSTS entry: Chr 12 RH118990
UniSTS entry: Chr 12 DYRK4_8858
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

NM_003845.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), mRNA PA
AF263541.1 Homo sapiens protein kinase DYRK4 (DYRK4) mRNA, partial cds P
AK292322.1 Homo sapiens cDNA FLJ76059 complete cds, highly similar to Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4), mRNA P
AK311576.1 Homo sapiens cDNA, FLJ18618
AK308702.1 Homo sapiens cDNA, FLJ98743 P
AK308260.1 Homo sapiens cDNA, FLJ98208 P
BC031244.1 Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4, mRNA (cDNA clone MGC:39640 IMAGE:5266287), complete cds PA
AK298979.1 Homo sapiens cDNA FLJ60811 complete cds, highly similar to Dual specificitytyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) P
AK303744.1 Homo sapiens cDNA FLJ61032 complete cds, highly similar to Dual specific itytyrosine-phosphorylation-regulated kinase 4 (EC 2.7.12.1) P
GU139746.1 Homo sapiens clone IMAGE:6622648 DYRK4 mRNA, partial sequence PA
GU139743.1 Homo sapiens clone IMAGE:5744824 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4-like (DYRK4) mRNA, partial sequence, alternatively spliced P
GU139744.1 Homo sapiens clone IMAGE:5850288 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139742.1 Homo sapiens clone IMAGE:5420658 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139741.1 Homo sapiens clone IMAGE:3574031 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139740.1 Homo sapiens clone IMAGE:3439581 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
GU139739.1 Homo sapiens clone IMAGE:2909975 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 (DYRK4) mRNA, partial cds, alternatively spliced PA
Y09305.1 H.sapiens mRNA for protein kinase, Dyrk4, partial P
GU139745.1 Homo sapiens clone IMAGE:6429142 noncoding RNA 152/DYRK4 breakpoint junction sequence PA

EST sequences (10 of 192) [Show all sequences]

AA968719.1 Clone IMAGE:1601148 uncharacterized tissue 3' read P
AI028591.1 Clone IMAGE:1644077 testis 3' read P
AI031860.1 Clone IMAGE:1668816 brain 3' read P
AA948356.1 Clone IMAGE:1589397 kidney 3' read P
AI066522.1 Clone IMAGE:1637621 uncharacterized tissue 3' read P
AI159902.1 Clone IMAGE:1704069 brain 3' read P
BX091456.1 Clone IMAGp998I05390_;_IMAGE:202444 mixed P
AI187736.1 Clone IMAGE:1738728 testis 3' read P
CB164202.1 Clone S23N672133-1-D02 stomach 5' read PA
AI291892.1 Clone IMAGE:1894602 placenta 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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