> Smoothened, frizzled family receptor (SMO)
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UGID:232883     UniGene Hs.437846     Homo sapiens (human)   SMO Order cDNA clone, Links
Smoothened, frizzled family receptor (SMO)

Human protein-coding gene SMO. Represented by 142 ESTs from 92 cDNA libraries. Corresponds to reference sequence NM_005631.4. [UniGene 232883 - Hs.437846]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005622.1 SMO gene product H. sapiens 100.0 786
XP_003896630.1 PREDICTED: smoothened homolog P. anubis 99.8 785
NP_795970.3 Smo gene product M. musculus 97.0 792
NP_001082084.1 smoothened X. laevis 84.4 780
NP_571102.1 smo gene product D. rerio 82.6 700
NP_523443.1 smoothened D. melanogaster 53.3 347
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_519371.3 PREDICTED: smoothened homolog isoform 2 P. troglodytes 99.5 785
XP_001093150.1 PREDICTED: smoothened homolog M. mulatta 99.4 785

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; testis; heart; prostate; amniotic fluid; mammary gland; lung; ovary; eye; uterus; adrenal gland; mixed; intestine; connective tissue; bone; kidney; muscle; uncharacterized tissue; bone marrow; thymus; skin; ear; pancreas; placenta
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q32.3
UniSTS entry: Chr 7 RH16231 [Map Viewer]
UniSTS entry: Chr 7 RH121944
UniSTS entry: Chr 7 RH12557 [Map Viewer]
UniSTS entry: Chr 7 MARC_16819-16820:1021560442:1
UniSTS entry: Chr 7 SMO_853
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF071494.1 Homo sapiens Gx protein (GX) mRNA, complete cds PA
NM_005631.4 Homo sapiens smoothened, frizzled family receptor (SMO), mRNA PA
AF130867.1 Homo sapiens smoothened mRNA, partial cds P
AF120103.1 Homo sapiens Gx protein mRNA, complete cds PA
BC009989.2 Homo sapiens smoothened homolog (Drosophila), mRNA (cDNA clone MGC:15193 IMAGE:4127774), complete cds PA
BC004332.1 Homo sapiens smoothened homolog (Drosophila), mRNA (cDNA clone IMAGE:3630958), with apparent retained intron PA
AF089720.1 Homo sapiens smoothened mRNA, 3' UTR
U84401.1 Human smoothened mRNA, complete cds P

EST sequences (10 of 142) [Show all sequences]

AF065154.1 Clone IMAGE:530958 uncharacterized tissue
AF065155.1 Clone IMAGE:530958 uncharacterized tissue
AI056937.1 Clone IMAGE:1669647 brain 3' read A
R21016.1 Clone IMAGE:36721 brain 5' read
AI081895.1 Clone IMAGE:1662329 mixed 3' read P
AI127817.1 Clone IMAGE:1711720 uterus 3' read A
AI140041.1 Clone IMAGE:1693706 heart 3' read A
AI160552.1 Clone IMAGE:1721171 uterus 3' read A
BX101123.1 Clone IMAGp998G06252_;_IMAGE:158237 mammary gland A
AI264951.1 Clone IMAGE:2006402 ovary 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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