> X-box binding protein 1 (XBP1)
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UGID:232675     UniGene Hs.437638     Homo sapiens (human)   XBP1
X-box binding protein 1 (XBP1)

Human protein-coding gene XBP1. Represented by 1336 ESTs from 384 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 232675 - Hs.437638]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001073007.1 XBP1 gene product H. sapiens 100.0 375
XP_515053.2 PREDICTED: X-box-binding protein 1 isoform 2 P. troglodytes 100.0 261
NP_001258659.1 X-box-binding protein 1 isoform XBP1(S) M. musculus 90.0 370
NP_571949.1 xbp1 gene product D. rerio 66.5 262
NP_001080523.1 X-box binding protein 1 X. laevis 63.4 374
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
NP_001258668.1 X-box binding protein 1 isoform XBP1(S) M. mulatta 99.2 375
XP_003904656.1 PREDICTED: uncharacterized protein LOC101003421 isoform 1 P. anubis 98.7 375

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; mammary gland; pancreas; uncharacterized tissue; uterus; testis; lung; intestine; brain; mixed; liver; prostate; embryonic tissue; salivary gland; eye; stomach; esophagus; bladder; skin; adrenal gland; blood; cervix; kidney; bone marrow; lymph; mouth; larynx; ovary; connective tissue; thyroid; heart; bone; ear; muscle; pharynx; parathyroid; lymph node; trachea; ascites; pineal gland; spleen; vascular; thymus; pituitary gland; nerve; adipose tissue; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q12.1|22q12
UniSTS entry: Chr 22 D22S1031
UniSTS entry: Chr 22 RH27882
UniSTS entry: Chr 22 STS-M31627
UniSTS entry: Chr 22 D22S1251 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

M31627.1 Human X box binding protein-1 (XBP-1) mRNA, complete cds PA
NM_005080.3 Homo sapiens X-box binding protein 1 (XBP1), transcript variant 1, mRNA PA
CR456611.1 Homo sapiens XBP1 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.XBP1.V2) P
BC000938.1 Homo sapiens X-box binding protein 1, mRNA (cDNA clone MGC:5436 IMAGE:3449394), complete cds PA
NM_001079539.1 Homo sapiens X-box binding protein 1 (XBP1), transcript variant 2, mRNA PA
BC012841.1 Homo sapiens X-box binding protein 1, mRNA (cDNA clone MGC:8980 IMAGE:3856898), complete cds PA
BC015709.1 Homo sapiens, clone IMAGE:3911945, mRNA, partial cds PA
AB076384.1 Homo sapiens XBP1 mRNA for X box-binding protein spliced form, complete cds P
AB076383.1 Homo sapiens XBP1 mRNA for X box-binding protein unspliced form, complete cds P
AK292188.1 Homo sapiens cDNA FLJ77362 complete cds, highly similar to Homo sapiens X-box binding protein 1 (XBP1), mRNA P
AK313761.1 Homo sapiens cDNA, FLJ94362 P
AK093842.1 Homo sapiens cDNA FLJ36523 fis, clone TRACH2002664 P

EST sequences (10 of 1336) [Show all sequences]

AA903693.1 Clone IMAGE:1517830 uncharacterized tissue 3' read A
AA975808.1 Clone IMAGE:1589507 kidney 3' read A
AA995422.1 Clone IMAGE:1612046 uncharacterized tissue 3' read A
AA996199.1 Clone IMAGE:1604120 lung 3' read A
AA922078.1 Clone IMAGE:1457252 intestine 3' read A
AI003698.1 Clone IMAGE:392089 pineal gland 3' read A
AI039414.1 Clone IMAGE:1658825 embryonic tissue 3' read A
AI040598.1 Clone IMAGE:1656403 mixed 3' read P
AI041493.1 Clone IMAGE:1648199 parathyroid 3' read A
AI051873.1 Clone IMAGE:1659330 embryonic tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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