> Clusterin (CLU)
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UGID:231694     UniGene Hs.436657     Homo sapiens (human)   CLU Order cDNA clone, Links
Clusterin (CLU)

Human protein-coding gene CLU. Represented by 4978 ESTs from 663 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 231694 - Hs.436657]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001822.3 CLU gene product H. sapiens 100.0 448
XP_519677.2 PREDICTED: clusterin isoform 15 P. troglodytes 99.6 500
NP_038520.2 Clu gene product M. musculus 84.2 447
NP_001080775.1 clusterin precursor X. laevis 52.1 439
NP_957096.1 clu gene product D. rerio 51.8 442
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_003902636.1 PREDICTED: clusterin isoform 3 P. anubis 98.3 459
XP_001109522.2 PREDICTED: clusterin M. mulatta 98.0 500

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; connective tissue; eye; testis; liver; thyroid; pancreas; uncharacterized tissue; uterus; mammary gland; mixed; ovary; lung; kidney; placenta; bone; nerve; prostate; stomach; ganglia; embryonic tissue; pineal gland; larynx; blood; intestine; lymph node; muscle; heart; cervix; parathyroid; adrenal gland; tonsil; ear; bladder; mouth; adipose tissue; amniotic fluid; pituitary gland; salivary gland; skin; epididymis; spinal cord; ascites; vascular; pharynx; esophagus; umbilical cord; spleen; peritoneum
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p21-p12
UniSTS entry: Chr 8 RH11712 [Map Viewer]
UniSTS entry: Chr 8 STS-J02908
UniSTS entry: Chr 8 RH27907
UniSTS entry: Chr 8 PMC310777P3
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 10 STS-N93746 [Map Viewer]
UniSTS entry: Chr 10 RH79633
UniSTS entry: RH47515
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

M64722.1 Human TRPM-2 mRNA, complete cds P
NM_001831.3 Homo sapiens clusterin (CLU), transcript variant 1, mRNA PA
J02908.1 Human apolipoprotein J mRNA, complete cds P
AY513288.1 Homo sapiens aging-associated protein 4 (AAG4) mRNA, complete cds PA
M74816.1 Human sulfated glycoprotein-2 mRNA, 3'end P
BC010514.1 Homo sapiens clusterin, mRNA (cDNA clone MGC:18080 IMAGE:4150452), complete cds PA
X14723.1 Human SP-40,40 mRNA for complement-associated protein SP-40,40 alpha-1 and beta-1 chain PA
BC019588.2 Homo sapiens clusterin, mRNA (cDNA clone MGC:24903 IMAGE:4915444), complete cds PA
AK313870.1 Homo sapiens cDNA, FLJ94503, highly similar to Homo sapiens clusterin (complement lysis inhibitor, SP-40,40,sulfated glycoprotein 2, testosterone-repressed prostate message 2,apolipoprotein J) (CLU), mRNA P
BC013221.1 Homo sapiens clusterin, mRNA (cDNA clone IMAGE:4149765) PA
M26639.1 Human sulfated glycoprotein 2 mRNA, partial cds
NR_045494.1 Homo sapiens clusterin (CLU), transcript variant 4, non-coding RNA PA
NR_038335.1 Homo sapiens clusterin (CLU), transcript variant 3, non-coding RNA PA
M25915.1 Human complement cytolysis inhibitor (CLI) mRNA, complete cds P

EST sequences (10 of 4978) [Show all sequences]

AA947833.1 Clone IMAGE:1374973 ovary P
AA968727.1 Clone IMAGE:1601153 uncharacterized tissue 3' read A
AA970348.1 Clone IMAGE:1576380 intestine 3' read A
AA973974.1 Clone IMAGE:1585223 lung 3' read A
AA975778.1 Clone IMAGE:1589469 kidney 3' read A
AA984319.1 Clone IMAGE:1629770 brain 3' read
AA984522.1 Clone IMAGE:1630173 brain 3' read P
AA984808.1 Clone IMAGE:1630659 brain 3' read
AI000375.1 Clone IMAGE:1614039 uncharacterized tissue 3' read A
AA905790.1 Clone IMAGE:1505064 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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