Anaphase promoting complex subunit 1 (ANAPC1)

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UGID:231564 UniGene Hs.436527 Homo sapiens (human) ANAPC1

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Anaphase promoting complex subunit 1 (ANAPC1)

Human protein-coding gene ANAPC1. Represented by 205 ESTs from 135 cDNA libraries. Corresponds to reference sequence NM_022662.3. [UniGene 231564 - Hs.436527]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_073153.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ANAPC1 gene product	H. sapiens	100.0	1943
XP_515601.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: anaphase-promoting complex subunit 1, partial	P. troglodytes	99.9	1394
XP_003909173.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: anaphase-promoting complex subunit 1-like	P. anubis	99.6	1943
NP_032595.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Anapc1 gene product	M. musculus	95.0	1943
XP_001921168.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: anaphase-promoting complex subunit 1	D. rerio	74.3	1975
NP_573025.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	shattered, isoform A	D. melanogaster	55.7	610
XP_959459.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein NCU05901	N. crassa	48.8	211
Other hits (2 of 41) [Show all]		Species	Id(%)	Len(aa)
XP_532958.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: anaphase-promoting complex subunit 1	C. lupus familiaris	98.6	1942
XP_001494848.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: anaphase-promoting complex subunit 1	E. caballus	98.3	1943

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; mixed; uncharacterized tissue; intestine; umbilical cord; salivary gland; lung; stomach; lymph; adipose tissue; cervix; thyroid; uterus; ovary; amniotic fluid; kidney; ear; connective tissue; placenta; trachea; spleen; bladder; ascites; bone; mammary gland; pancreas; testis; skin; liver; muscle; embryonic tissue; lymph node; prostate; thymus; mouth; adrenal gland; blood

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	2
Map position:	2q12.1
UniSTS entry:	Chr 2	D2S2914
UniSTS entry:	Chr 2	RH65352	[Map Viewer]
UniSTS entry:	Chr 2	G16417
UniSTS entry:		RH93456
UniSTS entry:	Chr 1	D11S2921

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK023807.1	Homo sapiens cDNA FLJ13745 fis, clone PLACE3000244, highly similar to PROTEIN TSG24 (MEIOTIC CHECK POINT REGULATOR)	P
BC104904.1	Homo sapiens anaphase promoting complex subunit 1, mRNA (cDNA clone MGC:132564 IMAGE:8143907), complete cds	P
BC104902.1	Homo sapiens anaphase promoting complex subunit 1, mRNA (cDNA clone MGC:132562 IMAGE:8143905), complete cds	P
NM_022662.3	Homo sapiens anaphase promoting complex subunit 1 (ANAPC1), mRNA	PA
AJ278357.1	Homo sapiens mRNA for Tsg24 protein	P
DQ786300.1	Homo sapiens clone HLS_IMAGE_731433 mRNA sequence	A
DQ786207.1	Homo sapiens clone HLS_IMAGE_1534603 mRNA sequence
BC005089.1	Homo sapiens anaphase promoting complex subunit 1, mRNA (cDNA clone IMAGE:3834642), partial cds	PA
AK094527.1	Homo sapiens cDNA FLJ37208 fis, clone BRALZ2007790, highly similar to Meiotic checkpoint regulator	P
AL832013.1	Homo sapiens mRNA; cDNA DKFZp451E124 (from clone DKFZp451E124)	PA

EST sequences (10 of 205) [Show all sequences]

AA907021.1	Clone IMAGE:1505748	mixed	3' read	PA
AA910409.1	Clone IMAGE:1505748	mixed	3' read	A
AA923514.1	Clone IMAGE:1534603	kidney	3' read	A
AA865116.1	Clone IMAGE:1371492	lymph node	3' read	A
CB054641.1	Clone IMAGE:3291684	brain	3' read	A
CB054642.1	Clone IMAGE:3291684	brain	5' read
CB055288.1	Clone IMAGE:3291911	brain	3' read	A
CB055289.1	Clone IMAGE:3291911	brain	5' read
CB136404.1	Clone L6ChoCK0-31-A11	liver	5' read	P
AI276624.1	Clone IMAGE:1877069	mixed	3' read	PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria