> Mesencephalic astrocyte-derived neurotrophic factor (MANF)
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UGID:231483     UniGene Hs.436446     Homo sapiens (human)   MANF Order cDNA clone, Links
Mesencephalic astrocyte-derived neurotrophic factor (MANF)

Human protein-coding gene MANF. Represented by 407 ESTs from 152 cDNA libraries. Corresponds to reference sequence NM_006010.4. [UniGene 231483 - Hs.436446]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006001.3 MANF gene product H. sapiens 100.0 181
NP_083379.2 Manf gene product M. musculus 98.9 178
NP_001070097.1 manf gene product D. rerio 82.0 177
NP_477445.1 mesencephalic astrocyte-derived neurotrophic factor D. melanogaster 61.4 153
NP_500273.2 Protein Y54G2A.23 C. elegans 59.1 164
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003894407.1 PREDICTED: LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor P. anubis 98.7 228
NP_001101653.1 Manf gene product R. norvegicus 98.4 121

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: pancreas; skin; brain; eye; lung; mixed; placenta; heart; liver; larynx; prostate; intestine; thymus; connective tissue; testis; uncharacterized tissue; ovary; embryonic tissue; ear; uterus; kidney; pituitary gland; mammary gland; blood; adrenal gland; bone marrow; thyroid; ascites; lymph node; bone; salivary gland; umbilical cord; stomach; lymph; nerve; vascular; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p21.1
UniSTS entry: Chr 3 SGC32878 [Map Viewer]
UniSTS entry: Chr 3 RH1498
UniSTS entry: Chr 3 D3S4001 [Map Viewer]
UniSTS entry: Chr 3 D17914
UniSTS entry: Chr 3 D3S1679
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BT007110.1 Homo sapiens arginine-rich, mutated in early stage tumors mRNA, complete cds P
NM_006010.4 Homo sapiens mesencephalic astrocyte-derived neurotrophic factor (MANF), mRNA PA
BC113588.1 Homo sapiens arginine-rich, mutated in early stage tumors, mRNA (cDNA clone MGC:142148 IMAGE:8322640), complete cds P
BC113590.1 Homo sapiens arginine-rich, mutated in early stage tumors, mRNA (cDNA clone MGC:142150 IMAGE:8322642), complete cds P
BC007282.1 Homo sapiens arginine-rich, mutated in early stage tumors, mRNA (cDNA clone IMAGE:3343642), partial cds PA
AK292243.1 Homo sapiens cDNA FLJ77177 complete cds, highly similar to Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA PA
M83751.1 Human arginine-rich protein (ARP) gene, complete cds PA

EST sequences (10 of 407) [Show all sequences]

AA906340.1 Clone IMAGE:1505933 mixed 3' read
AA974308.1 Clone IMAGE:1585960 uncharacterized tissue 3' read A
AA995530.1 Clone IMAGE:1606637 kidney 3' read A
AA999957.1 Clone IMAGE:1636503 kidney 3' read P
AI001979.1 Clone IMAGE:1619167 testis 3' read
AI016832.1 Clone IMAGE:1639122 testis 3' read P
AA926934.1 Clone IMAGE:1552366 uncharacterized tissue 3' read P
AI022022.1 Clone IMAGE:1652328 mixed 3' read PA
AI032929.1 Clone IMAGE:1655281 mixed 3' read
AI074336.1 Clone IMAGE:1682014 skin 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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