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UGID:231068     UniGene Hs.436031     Homo sapiens (human)   IREB2
Iron-responsive element binding protein 2 (IREB2)

Human protein-coding gene IREB2. Represented by 381 ESTs from 180 cDNA libraries. Corresponds to reference sequence NM_004136.2. [UniGene 231068 - Hs.436031]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_523125.2 PREDICTED: iron-responsive element-binding protein 2 isoform 4 P. troglodytes 100.0 962
NP_004127.1 IREB2 gene product H. sapiens 100.0 962
XP_003901319.1 PREDICTED: LOW QUALITY PROTEIN: iron-responsive element-binding protein 2 P. anubis 99.6 963
NP_073146.2 Ireb2 gene product M. musculus 95.7 962
XP_001341791.3 PREDICTED: iron-responsive element binding protein 2 D. rerio 76.8 750
NP_001084628.1 iron-responsive element-binding protein 2 X. laevis 74.0 952
NP_509898.1 Protein ACO-1 C. elegans 63.6 750
NP_477371.1 iron regulatory protein 1A D. melanogaster 62.8 881
NP_195308.1 aconitate hydratase 1 A. thaliana 56.9 881
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_001107837.1 PREDICTED: iron-responsive element-binding protein 2-like M. mulatta 99.5 963
XP_004017866.1 PREDICTED: iron-responsive element-binding protein 2 O. aries 97.4 963

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; mixed; vascular; uncharacterized tissue; bladder; embryonic tissue; bone marrow; thyroid; prostate; larynx; placenta; lung; pharynx; pancreas; skin; mouth; ovary; spleen; mammary gland; adrenal gland; thymus; kidney; intestine; trachea; uterus; liver; lymph node; blood; stomach; adipose tissue; cervix; connective tissue; eye; muscle; ascites; bone; parathyroid; ear
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q25.1
UniSTS entry: Chr 15 SHGC-36650 [Map Viewer]
UniSTS entry: Chr 15 G43287
UniSTS entry: Chr 15 RH77805 [Map Viewer]
UniSTS entry: Chr 15 IREB2
UniSTS entry: Chr 15 STS-R99019 [Map Viewer]
UniSTS entry: Chr 15 D15S908 [Map Viewer]
UniSTS entry: Chr 15 RH44971 [Map Viewer]
UniSTS entry: Chr 15 A009V40 [Map Viewer]
UniSTS entry: Chr 1 D10S275
UniSTS entry: Chr 15 G32892
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AL117613.1 Homo sapiens mRNA; cDNA DKFZp564D1164 (from clone DKFZp564D1164) A
NM_004136.2 Homo sapiens iron-responsive element binding protein 2 (IREB2), mRNA P
AL133439.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 200978 P
AB209403.1 Homo sapiens mRNA for iron-responsive element binding protein 2 variant protein P
AK027033.1 Homo sapiens cDNA: FLJ23380 fis, clone HEP16267, highly similar to HUMIREBPA Human iron-responsive element-binding protein/iron regulatory protein 2 (IRE-BP2/IRP2) mRNA PA
AK027034.1 Homo sapiens cDNA: FLJ23381 fis, clone HEP16268, highly similar to HUMIREBPA Human iron-responsive element-binding protein/iron regulatory protein 2 (IRE-BP2/IRP2) mRNA PA
BC117483.1 Homo sapiens iron-responsive element binding protein 2, mRNA (cDNA clone MGC:151092 IMAGE:40126034), complete cds P
BC117481.1 Homo sapiens iron-responsive element binding protein 2, mRNA (cDNA clone MGC:151090 IMAGE:40126032), complete cds P
BC017880.1 Homo sapiens iron-responsive element binding protein 2, mRNA (cDNA clone IMAGE:4277855), complete cds PA
AK292992.1 Homo sapiens cDNA FLJ77383 complete cds, highly similar to Homo sapiens iron-responsive element binding protein 2 (IREB2), mRNA P
M58511.1 Human iron-responsive element-binding protein/iron regulatory protein 2 (IRE-BP2/IRP2) mRNA, partial cds P
AF147302.1 Homo sapiens full length insert cDNA clone YA77A08 A
BC143948.1 Homo sapiens cDNA clone IMAGE:9052466 P
AB586699.1 Homo sapiens IREB2 variant mRNA for iron-responsive element binding protein 2 variant, complete cds P
U20180.1 Human iron-regulatory protein 2 (IRP2) mRNA, partial cds P

EST sequences (10 of 381) [Show all sequences]

AA947739.1 Clone IMAGE:1588076 uncharacterized tissue 3' read A
AI079804.1 Clone IMAGE:1668615 parathyroid 3' read A
AI090423.1 Clone IMAGE:1672329 uncharacterized tissue 3' read PA
BX099613.1 Clone IMAGp998G18213_;_IMAGE:143273 placenta A
BX106198.1 Clone IMAGp998M21654_;_IMAGE:293564 mixed
R31153.1 Clone IMAGE:134233 placenta 5' read
CB136536.1 Clone L5HLK1-37-F08 liver 5' read
CB132839.1 Clone L14ChoiCK0-7-E07 liver 5' read
AA693339.1 Clone IMAGE:1157102 kidney 3' read
AI202157.1 Clone IMAGE:1860137 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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