> Arrestin, beta 2 (ARRB2)
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UGID:230848     UniGene Hs.435811     Homo sapiens (human)   ARRB2
Arrestin, beta 2 (ARRB2)

Human protein-coding gene ARRB2. Represented by 405 ESTs from 194 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 230848 - Hs.435811]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003315363.1 PREDICTED: beta-arrestin-2 isoform 2 P. troglodytes 100.0 429
NP_001244257.1 ARRB2 gene product H. sapiens 100.0 429
XP_001095095.2 PREDICTED: beta-arrestin-2 isoform 2 M. mulatta 99.8 429
XP_003912181.1 PREDICTED: beta-arrestin-2 isoform 2 P. anubis 99.5 420
XP_002718869.1 PREDICTED: arrestin, beta 2-like O. cuniculus 99.5 408
NP_001258287.1 beta-arrestin-2 isoform a M. musculus 98.1 420
NP_001085581.1 beta-arrestin-2 X. laevis 91.1 405
NP_957418.1 arrb2b gene product D. rerio 88.7 407
NP_524988.1 kurtz, isoform A D. melanogaster 62.7 466
NP_508183.1 Protein ARR-1 C. elegans 58.4 418
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_003131971.3 PREDICTED: beta-arrestin-2 isoform 1 S. scrofa 99.3 415
XP_001503014.1 PREDICTED: beta-arrestin-2 E. caballus 98.8 414

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; mixed; lung; blood; eye; pancreas; thymus; cervix; adipose tissue; pituitary gland; testis; intestine; placenta; lymph node; muscle; embryonic tissue; thyroid; heart; spleen; prostate; bone; liver; kidney; stomach; uterus; vascular; mammary gland; connective tissue; skin; lymph; tonsil; ascites; ganglia; nerve; bone marrow; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13
UniSTS entry: Chr 17 RH18345 [Map Viewer]
UniSTS entry: Chr 17 WI-11146 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

AF106941.1 Homo sapiens beta-arrestin 2 mRNA, complete cds P
NM_004313.3 Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 1, mRNA PA
NM_199004.1 Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 2, mRNA PA
BC067368.1 Homo sapiens arrestin, beta 2, mRNA (cDNA clone MGC:74602 IMAGE:5748319), complete cds PA
CR450310.1 Homo sapiens full open reading frame cDNA clone RZPDo834E101D for gene ARRB2, arrestin, beta 2; complete cds; without stopcodon P
CR749218.1 Homo sapiens mRNA; cDNA DKFZp686L0365 (from clone DKFZp686L0365) PA
AB209786.1 Homo sapiens mRNA for arrestin beta 2 isoform 1 variant protein P
BC095450.1 Homo sapiens arrestin, beta 2, mRNA (cDNA clone IMAGE:30370950) PA
DQ664180.1 Homo sapiens beta arrestin 2 splice variant (ARRB2) mRNA, complete cds, alternatively spliced P
BC007427.2 Homo sapiens arrestin, beta 2, mRNA (cDNA clone MGC:3754 IMAGE:3028154), complete cds PA
AK290951.1 Homo sapiens cDNA FLJ76796 complete cds, highly similar to Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 2, mRNA P
AK097542.1 Homo sapiens cDNA FLJ40223 fis, clone TESTI2021851, highly similar to BETA-ARRESTIN 2 P
AK297181.1 Homo sapiens cDNA FLJ56622 complete cds, highly similar to Beta-arrestin-2 PA
AK297059.1 Homo sapiens cDNA FLJ58316 complete cds, highly similar to Beta-arrestin-2 P
EU883572.1 Homo sapiens arrestin beta 2 transcript variant 1 (ARRB2) mRNA, complete cds P
Z11501.1 H.sapiens mRNA for arrestin (partial) P
NM_001257330.1 Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 5, mRNA PA
NM_001257329.1 Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 4, mRNA PA
NM_001257331.1 Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 6, mRNA PA
NM_001257328.1 Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 3, mRNA PA
NR_047516.1 Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 7, non-coding RNA PA
BC039066.1 Homo sapiens, similar to arrestin, beta 2, clone IMAGE:5190699, mRNA PA

EST sequences (10 of 405) [Show all sequences]

AA973636.1 Clone IMAGE:1569403 lung 3' read A
R16483.1 Clone IMAGE:128625 mixed 5' read
R16783.1 Clone IMAGE:128625 mixed 3' read A
AI032757.1 Clone IMAGE:1656248 mixed 3' read A
AI042380.1 Clone IMAGE:1660906 mixed 3' read
AA948189.1 Clone IMAGE:1584999 lung 3' read A
AI076421.1 Clone IMAGE:1674839 mixed 3' read A
AI129230.1 Clone IMAGE:1711862 uterus 3' read A
AI148150.1 Clone IMAGE:1704080 brain 3' read A
AI151040.1 Clone IMAGE:1704809 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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