Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (CDKN2D)

Restricted Expression:

adult [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

brain; blood; testis; uncharacterized tissue; pancreas; lung; mixed; liver; placenta; eye; muscle; prostate; skin; bone; embryonic tissue; lymph node; intestine; pharynx

NCBI

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UGID:230088 UniGene Hs.435051 Homo sapiens (human) CDKN2D

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Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (CDKN2D)

Human protein-coding gene CDKN2D. Represented by 155 ESTs from 56 cDNA libraries. EST representation biased toward adult. Corresponds to 2 reference sequences (different isoforms). [UniGene 230088 - Hs.435051]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_001165514.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cyclin-dependent kinase 4 inhibitor D isoform 1	P. troglodytes	100.0	165
NP_524145.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CDKN2D gene product	H. sapiens	100.0	165
NP_034008.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Cdkn2d gene product	M. musculus	92.8	165
NP_001086884.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	X. laevis	72.6	146
XP_002662282.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cyclin-dependent kinase inhibitor 2D-like	D. rerio	64.0	152
Other hits (2 of 16) [Show all]		Species	Id(%)	Len(aa)
XP_001102138.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cyclin-dependent kinase 4 inhibitor D isoform 1	M. mulatta	98.8	165
XP_003914942.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cyclin-dependent kinase 4 inhibitor D	P. anubis	98.8	165

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	19
Map position:	19p13
UniSTS entry:	Chr 19	RH66593	[Map Viewer]
UniSTS entry:	Chr 19	RH18055
UniSTS entry:	Chr 19	PMC303366P8
UniSTS entry:	Chr 19	SHGC-35402	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_001800.3	Homo sapiens cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (CDKN2D), transcript variant 1, mRNA	PA
CR542158.1	Homo sapiens full open reading frame cDNA clone RZPDo834A0224D for gene CDKN2D, cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); complete cds, without stopcodon	P
U40343.1	Human CDK inhibitor p19INK4d mRNA, complete cds	PA
BC001822.2	Homo sapiens cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4), mRNA (cDNA clone MGC:3718 IMAGE:3529045), complete cds	PA
NM_079421.2	Homo sapiens cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (CDKN2D), transcript variant 2, mRNA	PA
U20498.1	Human p19 protein mRNA, complete cds	P
U49399.1	Human inhibitor of cyclin-dependent kinase 4 d INK4d mRNA, complete cds	P

EST sequences (10 of 155) [Show all sequences]

AI057178.1	Clone IMAGE:1671915	uncharacterized tissue	3' read	P
AI073832.1	Clone IMAGE:1565846	mixed	3' read
AI095201.1	Clone IMAGE:1672428	uncharacterized tissue	3' read
AI221498.1	Clone IMAGE:1842142	mixed	3' read	P
AI268122.1	Clone IMAGE:1911413	lung	3' read	P
AI268736.1	Clone IMAGE:1910977	lung	3' read	P
CB141879.1	Clone L11SNU354s1-2-C03	liver	5' read
AI280899.1	Clone IMAGE:1872097	intestine	3' read	P
AI358864.1	Clone IMAGE:2012912	brain	3' read	A
AI383407.1	Clone IMAGE:2074081	uncharacterized tissue	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria