> ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 (AGAP1)
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UGID:230076     UniGene Hs.435039     Homo sapiens (human)   AGAP1 Order cDNA clone, Links
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 (AGAP1)

Human protein-coding gene AGAP1. Represented by 235 ESTs from 150 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 230076 - Hs.435039]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001032208.1 AGAP1 gene product H. sapiens 100.0 856
XP_001082607.1 PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 1 M. mulatta 99.7 856
NP_835220.1 Agap1 gene product M. musculus 98.7 856
NP_001084915.1 arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 X. laevis 93.4 863
XP_001921526.2 PREDICTED: centaurin, gamma 2-like D. rerio 92.1 796
NP_723849.1 centaurin gamma 1A, isoform B D. melanogaster 57.3 900
NP_001022837.1 Protein CNT-2, isoform b C. elegans 54.0 878
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_848466.2 PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 C. lupus familiaris 99.4 803
XP_001915945.2 PREDICTED: LOW QUALITY PROTEIN: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1-like E. caballus 99.2 837

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; mammary gland; esophagus; testis; muscle; connective tissue; nerve; pineal gland; thyroid; amniotic fluid; placenta; pharynx; kidney; pancreas; embryonic tissue; intestine; mixed; uncharacterized tissue; lung; stomach; liver; uterus; ascites; heart; bone; skin; prostate; adipose tissue; ganglia; vascular; adrenal gland; blood; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q37
UniSTS entry: Chr 2 RH12556
UniSTS entry: Chr 2 RH102352
UniSTS entry: A009Q29
UniSTS entry: G32783
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AY033765.1 Homo sapiens GTP-binding and GTPase-activating protein 1 mRNA, complete cds P
AB029022.1 Homo sapiens mRNA for KIAA1099 protein, partial cds P
BC060814.1 Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, mRNA (cDNA clone IMAGE:30333116), complete cds PA
AK001722.1 Homo sapiens cDNA FLJ10860 fis, clone NT2RP4001568, weakly similar to ZINC FINGER PROTEIN GCS1 P
NM_014914.4 Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 (AGAP1), transcript variant 2, mRNA PA
NM_001037131.2 Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 (AGAP1), transcript variant 1, mRNA PA
AF413078.1 Homo sapiens centaurin gamma2 mRNA, complete cds P
BC167157.1 Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, mRNA (cDNA clone MGC:176692 IMAGE:8862571), complete cds PA
BC167153.1 Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, mRNA (cDNA clone MGC:176671 IMAGE:8862550), complete cds PA
BC140856.1 Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 1, mRNA (cDNA clone MGC:176533 IMAGE:9021724), complete cds P
AK300763.1 Homo sapiens cDNA FLJ58493 complete cds, highly similar to Centaurin-gamma 2 P
AK295520.1 Homo sapiens cDNA FLJ57841 complete cds, highly similar to Centaurin-gamma 2 P
NM_001244888.1 Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 (AGAP1), transcript variant 2, mRNA PA

EST sequences (10 of 235) [Show all sequences]

AA954932.1 Clone IMAGE:1574430 kidney 3' read A
AA977626.1 Clone IMAGE:1561199 mixed 3' read A
AA988159.1 Clone IMAGE:1603254 lung 3' read
AA906990.1 Clone IMAGE:1521972 lung 3' read
AI018451.1 Clone IMAGE:1641971 testis 3' read P
AI042513.1 Clone IMAGE:1660950 mixed 3' read A
AI078116.1 Clone IMAGE:1676268 embryonic tissue 3' read A
AI093059.1 Clone IMAGE:1694629 heart 3' read A
BX096592.1 Clone IMAGp998N19261_;_IMAGE:161874 mammary gland
BX095718.1 Clone IMAGp998L124602_;_IMAGE:1879067 mixed A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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