> Protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B)
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UGID:228567     UniGene Hs.433068     Homo sapiens (human)   PRKAR2B
Protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B)

Human protein-coding gene PRKAR2B. Represented by 217 ESTs from 118 cDNA libraries. Corresponds to reference sequence NM_002736.2. [UniGene 228567 - Hs.433068]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001148361.2 PREDICTED: cAMP-dependent protein kinase type II-beta regulatory subunit isoform 1 P. troglodytes 100.0 417
NP_002727.2 PRKAR2B gene product H. sapiens 100.0 417
XP_003896505.1 PREDICTED: LOW QUALITY PROTEIN: cAMP-dependent protein kinase type II-beta regulatory subunit P. anubis 99.5 419
NP_035288.2 Prkar2b gene product M. musculus 98.8 415
NP_001084637.1 protein kinase, cAMP-dependent, regulatory, type II, beta X. laevis 85.0 401
NP_001070838.2 prkar2aa gene product D. rerio 76.0 395
NP_523671.1 cAMP-dependent protein kinase R2, isoform A D. melanogaster 52.6 302
XP_961532.1 cAMP-dependent protein kinase regulatory subunit N. crassa 47.0 285
NP_012231.1 Bcy1p S. cerevisiae 46.0 189
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_001089109.2 PREDICTED: cAMP-dependent protein kinase type II-beta regulatory subunit M. mulatta 99.3 432
NP_777074.1 PRKAR2B gene product B. taurus 99.0 417

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; testis; mammary gland; eye; skin; prostate; blood; vascular; ovary; kidney; lung; embryonic tissue; uncharacterized tissue; adipose tissue; mixed; heart; lymph; pancreas; stomach; salivary gland; adrenal gland; lymph node; bone marrow; pituitary gland; trachea; larynx; nerve; intestine; bone; parathyroid; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q22
UniSTS entry: Chr 7 SHGC-30240 [Map Viewer]
UniSTS entry: Chr 7 D7S2773 [Map Viewer]
UniSTS entry: Chr 7 RH69117 [Map Viewer]
UniSTS entry: Chr 15 Rnu2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AK128639.1 Homo sapiens cDNA FLJ46798 fis, clone TRACH3031660, highly similar to cAMP-dependent protein kinase type II-beta regulatory subunit P
NM_002736.2 Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B), mRNA PA
BC075800.1 Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, beta, mRNA (cDNA clone MGC:87711 IMAGE:30331962), complete cds PA
M31158.1 Human cAMP-dependent protein kinase subunit RII-beta mRNA, complete cds P
AK291441.1 Homo sapiens cDNA FLJ77303 complete cds, highly similar to Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B), mRNA P
BC014355.1 Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, beta, mRNA (cDNA clone IMAGE:3686556), with apparent retained intron A

EST sequences (10 of 217) [Show all sequences]

AA991328.1 Clone IMAGE:1606991 mammary gland 3' read A
AA887427.1 Clone IMAGE:1501715 kidney 3' read
AI025657.1 Clone IMAGE:1645859 parathyroid 3' read
AI081026.1 Clone IMAGE:1632376 mammary gland 3' read A
CB047534.1 Clone IMAGE:3253346 kidney 5' read
BX098528.1 Clone IMAGp998J23698_;_IMAGE:310390 skin
AI224607.1 Clone IMAGE:1998945 stomach 3' read A
AI341761.1 Clone IMAGE:1938723 embryonic tissue 3' read
AI424780.1 Clone IMAGE:2095745 prostate 3' read A
AI582332.1 Clone IMAGE:2213809 lung 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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