> Nuclear receptor subfamily 1, group H, member 2 (NR1H2)
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UGID:228509     UniGene Hs.432976     Homo sapiens (human)   NR1H2 Order cDNA clone, Links
Nuclear receptor subfamily 1, group H, member 2 (NR1H2)

Human protein-coding gene NR1H2. Represented by 958 ESTs from 321 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 228509 - Hs.432976]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_009052.3 NR1H2 gene product H. sapiens 100.0 460
NP_001181626.1 oxysterols receptor LXR-beta M. mulatta 99.8 460
XP_003916000.1 PREDICTED: oxysterols receptor LXR-beta isoform 1 P. anubis 99.8 458
NP_033499.1 Nr1h2 gene product M. musculus 96.2 445
NP_001086083.1 nuclear receptor subfamily 1, group H, member 2 X. laevis 85.8 415
NP_001017545.1 nr1h3 gene product D. rerio 81.5 371
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_512838.4 PREDICTED: oxysterols receptor LXR-beta P. troglodytes 99.0 407
XP_851316.1 PREDICTED: oxysterols receptor LXR-beta isoform 1 C. lupus familiaris 97.6 454

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; skin; testis; placenta; lung; stomach; mixed; liver; uterus; thymus; muscle; eye; connective tissue; intestine; kidney; mammary gland; prostate; blood; embryonic tissue; bone; bone marrow; pancreas; spleen; bladder; ovary; adrenal gland; heart; vascular; thyroid; lymph node; cervix; tonsil; esophagus; trachea; lymph; salivary gland; nerve; adipose tissue; ascites; mouth; pharynx; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q13.3
UniSTS entry: Chr 19 RH70542
UniSTS entry: RH140629
UniSTS entry: Chr 1 GDB:182516
UniSTS entry: Chr 19 IB1639 [Map Viewer]
UniSTS entry: Chr 12 RH47016 [Map Viewer]
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BC047750.2 Homo sapiens nuclear receptor subfamily 1, group H, member 2, mRNA (cDNA clone MGC:54144 IMAGE:6469687), complete cds PA
CR456706.1 Homo sapiens full open reading frame cDNA clone RZPDo834F053D for gene NR1H2, nuclear receptor subfamily 1, group H, member 2; complete cds, incl. stopcodon P
BC074500.1 Homo sapiens nuclear receptor subfamily 1, group H, member 2, mRNA (cDNA clone MGC:64976 IMAGE:5211737), complete cds PA
CR749648.1 Homo sapiens mRNA; cDNA DKFZp686D1580 (from clone DKFZp686D1580) PA
U14534.1 Human orphan receptor mRNA, partial cds P
NM_007121.5 Homo sapiens nuclear receptor subfamily 1, group H, member 2 (NR1H2), transcript variant 1, mRNA PA
U07132.1 Human steroid hormone receptor Ner-I mRNA, complete cds P
BC007790.1 Homo sapiens nuclear receptor subfamily 1, group H, member 2, mRNA (cDNA clone MGC:14108 IMAGE:3636961), complete cds PA
AK290855.1 Homo sapiens cDNA FLJ77417 complete cds, highly similar to Human steroid hormone receptor Ner-I mRNA P
AK091535.1 Homo sapiens cDNA FLJ34216 fis, clone FCBBF3022005, highly similar to OXYSTEROLS RECEPTOR LXR-BETA P
AK297978.1 Homo sapiens cDNA FLJ57542 complete cds, highly similar to Oxysterols receptor LXR-beta P
AB307697.1 Homo sapiens NR1H2 mRNA for liver X receptor beta, complete cds P
BC033500.1 Homo sapiens nuclear receptor subfamily 1, group H, member 2, mRNA (cDNA clone MGC:35318 IMAGE:5178510), complete cds PA
HQ692835.1 Homo sapiens liver X nuclear receptor beta (NR1H2) mRNA, complete cds P
NM_001256647.1 Homo sapiens nuclear receptor subfamily 1, group H, member 2 (NR1H2), transcript variant 2, mRNA PA

EST sequences (10 of 958) [Show all sequences]

AA865394.1 Clone IMAGE:1459182 kidney 3' read A
AA975042.1 Clone IMAGE:1555572 kidney 3' read A
AA948222.1 Clone IMAGE:1587025 uncharacterized tissue 3' read
AI081544.1 Clone IMAGE:1555729 kidney 3' read A
AI127184.1 Clone IMAGE:1708217 heart 3' read A
AI143514.1 Clone IMAGE:1690334 mixed 3' read A
CB051454.1 Clone IMAGE:3289501 prostate 3' read P
CB051455.1 Clone IMAGE:3289501 prostate 5' read P
BX101626.1 Clone IMAGp998C19245_;_IMAGE:155466 mammary gland P
AI188976.1 Clone IMAGE:1724466 placenta 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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