Tripeptidyl peptidase II (TPP2)

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UGID:228196 UniGene Hs.432424 Homo sapiens (human) TPP2

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Tripeptidyl peptidase II (TPP2)

Human protein-coding gene TPP2. Represented by 457 ESTs from 168 cDNA libraries. Corresponds to reference sequence NM_003291.2. [UniGene 228196 - Hs.432424]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_001151602.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: tripeptidyl-peptidase 2	P. troglodytes	100.0	1248
NP_003282.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	TPP2 gene product	H. sapiens	100.0	1248
XP_002800874.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: tripeptidyl-peptidase 2-like	M. mulatta	99.9	1257
XP_003914099.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: tripeptidyl-peptidase 2	P. anubis	99.9	1241
NP_033444.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Tpp2 gene product	M. musculus	97.9	1261
NP_001085380.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	tripeptidyl peptidase II	X. laevis	86.2	1258
XP_002660367.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: tripeptidyl-peptidase 2-like	D. rerio	81.8	1248
NP_477247.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	tripeptidyl-peptidase II, isoform A	D. melanogaster	54.0	313
NP_193817.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	tripeptidyl peptidase ii	A. thaliana	53.5	583
XP_001695941.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein CHLREDRAFT_174517	C. reinhardtii	52.9	437
NP_495221.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein TPP-2	C. elegans	48.5	548
Other hits (2 of 43) [Show all]		Species	Id(%)	Len(aa)
XP_002713062.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: tripeptidyl peptidase II isoform 2	O. cuniculus	99.3	1248
XP_003639855.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: tripeptidyl-peptidase 2-like	C. lupus familiaris	98.8	1248

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	testis; brain; connective tissue; lung; mixed; uncharacterized tissue; prostate; eye; heart; thymus; liver; trachea; esophagus; lymph; mouth; embryonic tissue; intestine; mammary gland; stomach; vascular; skin; placenta; kidney; uterus; lymph node; salivary gland; ascites; muscle; bone; blood; adipose tissue; pancreas; cervix; ear; bone marrow; ovary; pharynx; adrenal gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	13
Map position:	13q32-q33
UniSTS entry:	Chr 13	SGC32558	[Map Viewer]
UniSTS entry:	Chr 13	RH17732	[Map Viewer]
UniSTS entry:	Chr 13	D13S1464	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

M73047.1	Homo sapiens tripeptidyl peptidase II mRNA, complete cds	P
AK127549.1	Homo sapiens cDNA FLJ45642 fis, clone COLON2007733, highly similar to Tripeptidyl-peptidase II (EC 3.4.14.10)	P
NM_003291.2	Homo sapiens tripeptidyl peptidase II (TPP2), mRNA	PA
M55169.1	Homo sapiens tripeptidyl peptidase II mRNA, 3' end	PA
AK097678.1	Homo sapiens cDNA FLJ40359 fis, clone TESTI2034357, moderately similar to TRIPEPTIDYL-PEPTIDASE II (EC 3.4.14.10)	P
BC024905.1	Homo sapiens tripeptidyl peptidase II, mRNA (cDNA clone IMAGE:4508093), with apparent retained intron	PA
AK304313.1	Homo sapiens cDNA FLJ61714 partial cds, highly similar to Tripeptidyl-peptidase 2 (EC 3.4.14.10)	P
BC039905.1	Homo sapiens tripeptidyl peptidase II, mRNA (cDNA clone MGC:47733 IMAGE:6067427), complete cds	PA

EST sequences (10 of 457) [Show all sequences]

AA866152.1	Clone IMAGE:1469430	uncharacterized tissue	3' read	A
AA968982.1	Clone IMAGE:1574645	kidney	3' read
AA975222.1	Clone IMAGE:1588406	uncharacterized tissue	3' read
AA991768.1	Clone IMAGE:1623848	embryonic tissue	3' read	A
AA992402.1	Clone IMAGE:1620442	testis	3' read	P
AA994655.1	Clone IMAGE:1626639	mixed	3' read
AI033042.1	Clone IMAGE:1654386	mixed	3' read	P
AI089861.1	Clone IMAGE:1686458	brain	3' read	P
AI084450.1	Clone IMAGE:1662096	mixed	3' read	P
AI149690.1	Clone IMAGE:1752719	testis	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria