> Phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1)
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UGID:227791     UniGene Hs.431173     Homo sapiens (human)   PLCB1 Order cDNA clone, Links
Phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1)

Human protein-coding gene PLCB1. Represented by 143 ESTs from 86 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 227791 - Hs.431173]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056007.1 PLCB1 gene product H. sapiens 100.0 1215
XP_001170216.3 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 P. troglodytes 100.0 1210
XP_001116017.1 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1-like M. mulatta 99.6 1215
NP_001139302.1 Plcb1 gene product M. musculus 98.6 1215
NP_001081169.1 phospholipase C, beta 3 (phosphatidylinositol-specific) X. laevis 68.1 1181
NP_001116245.1 plcb3 gene product D. rerio 64.7 1205
NP_995606.1 phospholipase C at 21C, isoform C D. melanogaster 55.3 885
NP_001021347.1 Protein EGL-8, isoform b C. elegans 54.2 902
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
XP_003905111.1 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like P. anubis 99.0 1165
XP_001493653.3 PREDICTED: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1-like E. caballus 98.9 1197

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; testis; liver; adipose tissue; uterus; kidney; mixed; intestine; mouth; muscle; ovary; thymus; trachea; lung; ear; connective tissue; embryonic tissue; eye; prostate; uncharacterized tissue; parathyroid; pancreas; pharynx; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20p12
UniSTS entry: Chr 20 D20S580E [Map Viewer]
UniSTS entry: Chr 20 A007B46
UniSTS entry: Chr 20 D20S594E [Map Viewer]
UniSTS entry: Chr 20 A006R17
UniSTS entry: Plcb1
UniSTS entry: Chr 20 RH69828
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_182734.2 Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 2, mRNA PA
AK127693.1 Homo sapiens cDNA FLJ45792 fis, clone NT2RI2004818, highly similar to 1-phosphatidylinositol-4,5-bisphosphatephosphodiesterase beta 1 (EC 3.1.4.11) P
AL137267.1 Homo sapiens mRNA; cDNA DKFZp434A0814 (from clone DKFZp434A0814); partial cds PA
BC069420.1 Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific), mRNA (cDNA clone MGC:97162 IMAGE:7262405), complete cds P
AJ278313.1 Homo sapiens mRNA for phospholipase C-beta-1a (PLCB1 gene) P
AJ278314.1 Homo sapiens mRNA for phospholipase C-beta-1b (PLCB1 gene) P
AY004175.1 Homo sapiens phospholipase C beta 1 mRNA, complete cds P
NM_015192.3 Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 1, mRNA PA
BC117231.1 Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific), mRNA (cDNA clone MGC:150840 IMAGE:40125782), complete cds P
AK310597.1 Homo sapiens cDNA, FLJ17639 P
AK299195.1 Homo sapiens cDNA FLJ57337 partial cds, highly similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) P
AB011153.3 Homo sapiens mRNA for KIAA0581 protein, partial cds P

EST sequences (10 of 143) [Show all sequences]

AA984410.1 Clone IMAGE:1629935 brain 3' read P
AI057545.1 Clone IMAGE:1667392 parathyroid 3' read A
R20777.1 Clone IMAGE:130064 placenta 3' read
BX110946.1 Clone IMAGp998B02830_;_IMAGE:360865 eye
AI267242.1 Clone IMAGE:2035533 brain
CB115802.1 Clone L8SCK0-7-E05 liver 5' read
AI197885.1 Clone IMAGE:1859762 brain 3' read PA
AI241139.1 Clone IMAGE:1867315 kidney 3' read A
AI248321.1 Clone IMAGE:1850040 mixed 3' read PA
R36195.1 Clone IMAGE:136838 placenta 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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