> IQ motif containing GTPase activating protein 1 (IQGAP1)
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UGID:227571     UniGene Hs.430551     Homo sapiens (human)   IQGAP1 Order cDNA clone, Links
IQ motif containing GTPase activating protein 1 (IQGAP1)

Human protein-coding gene IQGAP1. Represented by 941 ESTs from 398 cDNA libraries. Corresponds to reference sequence NM_003870.3. [UniGene 227571 - Hs.430551]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_523157.3 PREDICTED: IQ motif containing GTPase activating protein 1 P. troglodytes 100.0 1656
NP_003861.1 IQGAP1 gene product H. sapiens 100.0 1656
XP_003901440.1 PREDICTED: ras GTPase-activating-like protein IQGAP1 P. anubis 99.8 1694
XP_002804991.1 PREDICTED: ras GTPase-activating-like protein IQGAP1-like M. mulatta 99.6 1701
NP_057930.2 Iqgap1 gene product M. musculus 98.4 1656
NP_001082590.1 IQ motif containing GTPase activating protein 1 X. laevis 90.0 1617
XP_001920847.3 PREDICTED: IQ motif containing GTPase activating protein 1, partial D. rerio 85.8 1604
NP_493492.1 Protein PES-7 C. elegans 46.8 156
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_003482273.1 PREDICTED: LOW QUALITY PROTEIN: IQ motif containing GTPase activating protein 1 S. scrofa 98.8 1603
XP_001498595.1 PREDICTED: IQ motif containing GTPase activating protein 1 E. caballus 98.8 1674

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mammary gland; brain; placenta; uterus; uncharacterized tissue; lung; intestine; liver; kidney; mouth; mixed; connective tissue; pancreas; skin; blood; muscle; trachea; prostate; adipose tissue; embryonic tissue; vascular; parathyroid; pharynx; testis; ovary; lymph node; stomach; thymus; esophagus; spleen; eye; heart; bladder; tonsil; ascites; bone; larynx; thyroid; pituitary gland; epididymis; lymph; bone marrow; adrenal gland; ganglia; cervix; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q26.1
UniSTS entry: Chr 15 RH17825
UniSTS entry: Chr 15 RH78456
UniSTS entry: D15S946
UniSTS entry: Chr 15 D15S1178 [Map Viewer]
UniSTS entry: Chr 15 RH25287
UniSTS entry: Chr 15 RH65701 [Map Viewer]
UniSTS entry: G43353
UniSTS entry: Chr 15 RH76514
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

NM_003870.3 Homo sapiens IQ motif containing GTPase activating protein 1 (IQGAP1), mRNA P
BC064971.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone IMAGE:6150095), partial cds PA
BC089385.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone IMAGE:6185052), partial cds PA
BC110811.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone IMAGE:6014074), partial cds PA
BC139731.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone MGC:134938 IMAGE:40073370), complete cds P
BC016714.1 Homo sapiens, clone IMAGE:4065996, mRNA A
BC151834.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone MGC:166899 IMAGE:9007269), complete cds P
AK307643.1 Homo sapiens cDNA, FLJ97591 P
AK298000.1 Homo sapiens cDNA FLJ55816 complete cds, highly similar to Ras GTPase-activating-like protein IQGAP1 P
AK304337.1 Homo sapiens cDNA FLJ55443 complete cds, highly similar to Ras GTPase-activating-like protein IQGAP1 P
BC037425.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone IMAGE:5539472), partial cds P
BC020549.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone IMAGE:3852746), partial cds PA
AF401205.1 Homo sapiens IQGAP1 protein mRNA, partial cds P
BC005906.1 Homo sapiens IQ motif containing GTPase activating protein 1, mRNA (cDNA clone IMAGE:4272972), partial cds PA
AL110106.1 Homo sapiens EST from clone 262918, 5' end
D29640.1 Homo sapiens KIAA0051 mRNA, partial cds P

EST sequences (10 of 941) [Show all sequences]

AA902595.1 Clone IMAGE:1502702 kidney 3' read A
AA910813.1 Clone IMAGE:1520916 lung 3' read
AI034042.1 Clone IMAGE:1646834 parathyroid 3' read A
T27115.1 Clone LLAB297C09 brain 5' read
AI051404.1 Clone IMAGE:1658849 embryonic tissue 3' read
AA946957.1 Clone IMAGE:1590179 kidney 3' read A
AI074688.1 Clone IMAGE:1662905 mixed 3' read A
R21941.1 Clone IMAGE:130682 placenta 5' read
R22589.1 Clone IMAGE:130682 placenta 3' read
AI122850.1 Clone IMAGE:1694965 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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